Search Results - "Avella, Michael"

Differential effects of low-density lipoprotein and chylomicron remnants on lipid accumulation in human macrophages by Batt, Kelly V, Avella, Michael, Moore, Elizabeth H, Jackson, Brian, Suckling, Keith E, Botham, Kathleen M

“…The effects of low-density lipoprotein (LDL) and chylomicron remnants on lipid accumulation in human monocyte-derived macrophages (HMDMs) and in macrophages…”
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Differential modulation of hepatic very low-density lipoprotein secretion by triacylglycerol-rich lipoproteins derived from different oleic-acid rich dietary oils by Perona, Javier S., Avella, Michael, Botham, Kathleen M., Ruiz-Gutierrez, Valentina

“…Minor components from dietary oils can modulate the atherogenic response of the TAG-rich lipoproteins (TRL) in which they are transported. In the present study…”
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The effects of dietary n-3 polyunsaturated fatty acids delivered in chylomicron remnants on the transcription of genes regulating synthesis and secretion of very-low-density lipoprotein by the liver: modulation by cellular oxidative state by Botham, Kathleen M, Zheng, Xiaozhong, Napolitano, Mariarosaria, Avella, Michael, Cavallari, Claudio, Rivabene, Roberto, Bravo, Elena

“…The influence of chylomicron remnants enriched in n-3 or n-6 polyunsaturated fatty acids (PUFA) (derived from fish or corn oil, respectively) on the expression…”
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Chylomicron-remnant-like particles inhibit receptor-mediated endothelium-dependent vasorelaxation in pig coronary arteries by Goulter, Andrew B, Avella, Michael A, Elliott, Jonathan, Botham, Kathleen M

“…The influence of native and oxidized chylomicron-remnant-like particles (CMR-LPs) on endothelium-dependent relaxation in pig coronary arteries was studied…”
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The influence of chylomicron remnants on endothelial cell function in the isolated perfused rat aorta by Grieve, David J, Avella, Michael A, Elliott, Jonathan, Botham, Kathleen M

“…A system for the perfusion of the isolated rat aorta which allowed the study of both the uptake of chylomicron remnants by the artery wall and their effects on…”
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Comparison of the effects of dietary n−3 and n−6 polyunsaturated fatty acids on very-low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnants by ZHENG, Xiaozhong, AVELLA, Michael, BOTHAM, Kathleen M.

“…The effects of chylomicron remnants enriched in n-3 or n-6 polyunsaturated fatty acids (derived from fish or corn oil respectively) on the secretion of…”
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Oxidation affects the regulation of hepatic lipid synthesis by chylomicron remnants by Napolitano, Mariarosaria, Rivabene, Roberto, Avella, Michael, Amicone, Laura, Tripodi, Marco, Botham, Kathleen M, Bravo, Elena

“…The effects of native and oxidized chylomicron remnants on lipid synthesis in normal and oxidatively stressed liver cells were investigated using MET murine…”
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The influence of chylomicron remnants on cholesteryl ester metabolism in cultured rat hepatocytes: comparison of the effects of particles enriched in n-3 or n-6 polyunsaturated fatty acids by Botham, Kathleen M, Maldonado, Eduardo N, Chico, Yolanda, Zheng, Xiaozhong, Avella, Michael, Ochoa, Begoña

“…The effect of chylomicron remnants derived from fish oil (rich in n-3 polyunsaturated fatty acids) or corn oil (rich in n-6 polyunsaturated fatty acids) on the…”
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Chylomicron remnants potentiate phenylephrine-induced contractions of rat aorta by an endothelium-dependent mechanism by Grieve, David J, Avella, Michael A, Botham, Kathleen M, Elliott, Jonathan

“…The effects of chylomicron remnants on endothelium-dependent contraction of rat aorta were studied in vitro. Chylomicron remnant particles were prepared in…”
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The differential hepatic uptake of chylomicron remnants of different fatty acid composition is not mediated by hepatic lipase by Lambert, Marc S., Avell, Michael A., Berhane, Yoel, Shervill, Elaine, Botham, Kathleen M.

“…The hypothesis that hepatic lipase mediates the differential hepatic uptake of chylomicron remnants of different fatty acid composition, demonstrated in…”
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Comparison of the hepatic uptake and processing of cholesterol from chylomicrons of different fatty acid composition in the rat in vivo by Bravo, Elena, Ortu, Giuseppina, Cantafora, Alfredo, Lambert, Marc S., Avella, Michael, Mayes, Peter A., Botham, Kathleen M.

“…The effect of the fatty acid composition of chylomicrons on the uptake and processing of the cholesterol they carry was investigated in the rat in vivo. Rats…”
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The fatty acid composition of chylomicron remnants influences their binding and internalization by isolated hepatocytes by Lambert, Marc S., Avella, MichaeL. A., Berhane, Yoel, Shervill, Elaine, Botham, Kathleen M.

“…The binding and internalization of 125I‐labelled chylomicron remnants derived from palm, olive, corn, or fish oil (rich in saturated, monounsaturated, n‐6, or…”
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Postprandial phase time influences the uptake of TAG from postprandial TAG-rich lipoproteins by THP-1 macrophages by Cabello-Moruno, Rosana, Sinausia, Laura, Botham, Kathleen M., Montero, Emilio, Avella, Michael, Perona, Javier S.

“…Postprandial TAG-rich lipoproteins (TRL) can be taken up by macrophages, leading to the formation of foam cells, probably via receptor-mediated pathways. The…”
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The interaction between oxidised chylomicron remnants and the aorta of rats fed a normocholesterolaemic or hypercholesterolaemic diet by Grieve, D J, Avella, M A, Elliott, J, Botham, K M

“…The effects of oxidised chylomicron remnants on endothelium-dependent relaxation and lipoprotein uptake were studied in both the normocholesterolaemic and…”
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Suppression of VLDL secretion by cultured hepatocytes incubated with chylomicron remnants enriched in n−3 polyunsaturated fatty acids is regulated by hepatic nuclear factor-4α by López-Soldado, Iliana, Avella, Michael, Botham, Kathleen M.

“…Dietary n− 3 polyunsaturated fatty acids (PUFA) suppress the secretion of very low density lipoprotein (VLDL) directly when delivered to the liver in…”
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Differential influence of different dietary fatty acids on very low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnants by López-Soldado, Iliana, Avella, Michael, Botham, Kathleen M

“…Abstract The influence of dietary fats carried in chylomicron remnants on the hepatic secretion of very low-density lipoprotein (VLDL) was investigated using…”
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Fatty acid composition of chylomicron remnant‐like particles influences their uptake and induction of lipid accumulation in macrophages by De Pascale, Clara, Avella, Michael, Perona, Javier S., Ruiz‐Gutierrez, Valentina, Wheeler‐Jones, Caroline P. D., Botham, Kathleen M.

“…The influence of the fatty acid composition of chylomicron remnant‐like particles (CRLPs) on their uptake and induction of lipid accumulation in macrophages…”
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Oxidation of chylomicron remnant-like particles inhibits their uptake by THP-1 macrophages by apolipoprotein E-dependent processes by Bejta, Fatos, Moore, Elizabeth H., Avella, Michael, Gough, Peter J., Suckling, Keith E., Botham, Kathleen M.

“…The influence of the oxidative state of chylomicron remnants (CMR) on the mechanisms of their uptake and induction of lipid accumulation by macrophages derived…”
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Chylomicron remnant induction of lipid accumulation in J774 macrophages is associated with up-regulation of triacylglycerol synthesis which is not dependent on oxidation of the particles by Napolitano, Mariarosaria, Avella, Michael, Botham, Kathleen M., Bravo, Elena

“…The influence of chylomicron remnants on lipid accumulation and synthesis and the activity and/or expression of mRNA for some of the key enzymes involved was…”
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Uptake of triacylglycerol-rich lipoproteins of differing triacylglycerol molecular species and unsaponifiable content by liver cells by Perona, Javier S., Avella, Michael, Botham, Kathleen M., Ruiz-Gutierrez, Valentina

“…The fatty acid composition of dietary oils can modulate the incorporation of triacylglycerol-rich lipoproteins (TRL) into hepatocytes, thus affecting the…”
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