Ovarian follicular response to different hormonal stimulation treatments in Canindé goats

The objective of the present study was to evaluate the effect of different hormonal stimulation treatments on the antral follicular population of naturalized Canindé goats. Adult goats (n =17) having estrous cycles at regular intervals were treated with intra-vaginal sponges containing 60mg medroxyp...

Full description

Saved in:

Bibliographic Details
Published in:	Animal reproduction science Vol. 125; no. 1-4; pp. 88 - 93
Main Authors:	Sousa, Francisco Carlos de, Melo, Carlos Henrique Sousa de, Albuquerque Teles Filho, Antônio Carlos de, Avelar, Suely Renata Gaya, Alencar Araripe Moura, Arlindo de, Martins, Jorge André Matias, Figueirêdo Freitas, Vicente José de, Teixeira, Dárcio Ítalo Alves
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01-05-2011 [Amsterdam]: Elsevier Science
Subjects:	acetates adults animal ovaries Animals Brazil Chorionic Gonadotropin - administration & dosage equine chorionic gonadotropin Female Follicle Stimulating Hormone - administration & dosage follicle-stimulating hormone Goats Goats - physiology Injections, Intramuscular - veterinary medroxyprogesterone Organ Size - drug effects Ovarian Follicle - diagnostic imaging Ovarian Follicle - drug effects Ovarian Follicle - physiology Ovarian follicular development Statistics, Nonparametric Ultrasonography Goats Ovarian follicular development Ultrasonography
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The objective of the present study was to evaluate the effect of different hormonal stimulation treatments on the antral follicular population of naturalized Canindé goats. Adult goats (n =17) having estrous cycles at regular intervals were treated with intra-vaginal sponges containing 60mg medroxyprogesterone acetate for 11 days, combined with an application of 50μg d-cloprostenol on the Day 8 of treatment. For ovarian stimulation, goats were distributed into the following experimental groups: (a) multiple doses (MD), with a total of 120mg NIH-FSH P1 in five intramuscular injections (30/30; 20/20 and 20mg) at 12-h intervals; (b) three doses (TD), with a total of 120mg NIH-FSH P1 in three intramuscular injections (60; 40 and 20mg) at 24h intervals; (c) one dose (OD), which consisted of the use of 70mg NIH-FSH P1 combined with 200IU eCG administered intramuscularly 36h before sponge removal. In the MD and TD groups, FSH injections were begun on the Day 8 of progestagen treatment. The ovaries of all animals were observed by transrectal real time ultrasonography (TRU) during the follicular stimulation protocols. All follicles ≥2mm were counted, measured and classified according to greatest diameter. The ultrasonographic assessment of the ovaries provided for well-defined ovarian structures. At the time of insertion of the sponges (Day 0), significant differences were observed (P <0.05) for the mean number of large follicles between the treated groups. Meanwhile, on Day 11, the three treatments did not differ (P <0.05), regardless of the follicular category. The diameter of small follicles was similar in MD, TD and OD during the whole period of the study. In the TD group, diameter of the large follicles was less (P <0.05) on Day 10 when compared to MD and OD. However, these differences were not observed on Day 11. In conclusion, the three treatments produced comparable distribution of the follicular populations. However, the single dose treatment can be preferred because of its simplicity and efficacious follicular response.
Bibliography:	http://dx.doi.org/10.1016/j.anireprosci.2011.02.015 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0378-4320 1873-2232
DOI:	10.1016/j.anireprosci.2011.02.015