Search Results - "Avdulov, N A"

Lipid Binding to Amyloid β‐Peptide Aggregates: Preferential Binding of Cholesterol as Compared with Phosphatidylcholine and Fatty Acids by Avdulov, Nicolai A., Chochina, Svetlana V., Igbavboa, Urule, Warden, Christopher S., Vassiliev, Alexei V., Wood, W. Gibson

“…: Amyloid β‐peptide (Aβ) aggregates are one of the key neuropathological characteristics of Alzheimer's disease. Aβ belongs to a group of proteins that…”
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Increasing age alters transbilayer fluidity and cholesterol asymmetry in synaptic plasma membranes of mice by Igbavboa, U, Avdulov, N A, Schroeder, F, Wood, W G

“…Previous studies examining age differences in membrane fluidity and cholesterol content have reported on the average or total change in membrane structure,…”
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Transbilayer Distribution of Cholesterol Is Modified in Brain Synaptic Plasma Membranes of Knockout Mice Deficient in the Low‐Density Lipoprotein Receptor, Apolipoprotein E, or Both Proteins by Igbavboa, Urule, Avdulov, Nicolai A., Chochina, Svetlana V., Wood, W. Gibson

“…: Both apolipoprotein E (apoE) and the low‐density lipoprotein (LDL) receptor are present in brain; however, little is known regarding the function of these…”
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Amyloid β‐Peptides Increase Annular and Bulk Fluidity and Induce Lipid Peroxidation in Brain Synaptic Plasma Membranes by Avdulov, Nicolai A., Chochina, Svetlana V., Igbavboa, Urule, O'Hare, Eugene O., Schroeder, Friedhelm, Cleary, James P., Wood, W. Gibson

“…: Amyloid β‐peptides (Aβ) may alter the neuronal membrane lipid environment by changing fluidity and inducing free radical lipid peroxidation. The effects of…”
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Cholesterol Efflux to High-Density Lipoproteins and Apolipoprotein A-I Phosphatidylcholine Complexes Is Inhibited by Ethanol:  Role of Apolipoprotein Structure and Cooperative Interaction of Phosphatidylcholine and Cholesterol by Avdulov, Nicolai A, Chochina, Svetlana V, Igbavboa, Urule, Wood, W. Gibson

“…There is a substantial body of evidence showing that moderate alcohol consumption is associated with a reduced risk of cardiovascular morbidity and mortality…”
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Amyloid beta-peptide1-40 increases neuronal membrane fluidity: role of cholesterol and brain region by Chochina, S V, Avdulov, N A, Igbavboa, U, Cleary, J P, O'Hare, E O, Wood, W G

“…There is increasing evidence of an interaction between cholesterol dynamics and Alzheimer's disease (AD), and amyloid beta-peptide may play an important role…”
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Effects of ethanol on structural parameters of rat brain membranes: relationship to genetic differences in ethanol sensitivity by Avdulov, N A, Wood, W G, Harris, R A

“…Fluorescent probes located in different membrane regions were used to evaluate effects of ethanol (50 and 100 mM) on structural parameters (protein…”
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Distribution and fluidizing action of soluble and aggregated amyloid beta-peptide in rat synaptic plasma membranes by Mason, R P, Jacob, R F, Walter, M F, Mason, P E, Avdulov, N A, Chochina, S V, Igbavboa, U, Wood, W G

“…The effects of soluble and aggregated amyloid beta-peptide (Abeta) on cortical synaptic plasma membrane (SPM) structure were examined using small angle x-ray…”
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Chronic ethanol consumption alters effects of ethanol in vitro on brain membrane structure of high alcohol sensitivity and low alcohol sensitivity rats by Avdulov, N A, Chochina, S V, Draski, L J, Deitrich, R A, Wood, W G

“…In this study, we examined if differences in initial membrane sensitivity to ethanol were associated with development of membrane tolerance to ethanol. High…”
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Recent advances in brain cholesterol dynamics: Transport, domains, and Alzheimer's disease by Wood, W. Gibson, Schroeder, Friedhelm, Avdulov, Nicolai A., Chochina, Svetlana V., Igbavboa, Urule

“…Major advances in understanding cholesterol dynamics and the role that cholesterol plays in vascular disease have recently been made. The brain is an organ…”
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Lipid binding to sterol carrier protein-2 is inhibited by ethanol by Avdulov, Nicolai A., Chochina, Svetlana V., Igbavboa, Urule, Warden, Christopher S., Schroeder, Friedhelm, Wood, W.Gibson

“…Sterol carrier protein-2 (SCP-2) is an intracellular lipid carrier protein that binds cholesterol, phospholipids, fatty acids and other ligands. It has been…”
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Specific Binding of Ethanol to Cholesterol in Organic Solvents by Daragan, Vladimir A., Voloshin, Alexei M., Chochina, Svetlana V., Khazanovich, Teodor N., Wood, W. Gibson, Avdulov, Nicolai A., Mayo, Kevin H.

“…Although ethanol has been reported to affect cholesterol homeostasis in biological membranes, the molecular mechanism of action is unknown. Here, nuclear…”
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Cholesterol oxidation reduces Ca2+ + Mg2+-ATPase activity, interdigitation, and increases fluidity of brain synaptic plasma membranes by WOOD, W. G, IGBAVBOA, U, MURALIKRISHNA RAO, A, SCHROEDER, F, AVDULOV, N. A

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Structure and Polarity of Mouse Brain Synaptic Plasma Membrane: Effects of Ethanol in vitro and in vivo by Colles, Scott, Wood, W. Gibson, Meyers-Payne, Sean, Joseph, Jim, Schroeder, Friedhelm

“…Structural and dielectric alteration by ethanol in vitro and chronic ethanol consumption were examined in synaptic plasma membranes (SPM) using…”
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Membrane-related effects of atypical antidepressants by Valdman, A V, Avdulov, N A

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Membrane aspects of chronic stress: effects of psychotropic drugs by Valdman, A V, Avdulov, N A, Eremenko, A V, Losev, A S

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Changes in synaptosomal membranes from cerebral cortex due to psychogenic stress in rats by Avdulov, N A, Eremenko, A V, Valdman, A V, Malin, K M, Bulatova, N R, Krinskaya, A V, Lukjanova, L D, Dudchenko, A M, Losev, A S

“…The changes in synaptosomal membranes in comparison with those of macrophages and mitochondria during repeated psychogenic stress were evaluated using a…”
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Spectra of psychotropic activity and neurochemical mechanisms of action of bi- and tetracyclic antidepressants by Kozlovskaya, M M, Avdulov, N A, Kushnaryov, V V

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Brain membrane cholesterol domains, aging and amyloid beta-peptides by Wood, W.Gibson, Schroeder, Friedhelm, Igbavboa, Urule, Avdulov, Nicolai A, Chochina, Svetlana V

“…Lipids are essential for the structural and functional integrity of membranes. Membrane lipids are not randomly distributed but are localized in different…”
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Behavioural and neurochemical studies of the action of atypical antidepressants by Valdman, A V, Avdulov, N A, Rozganets, V V, Rusacov, D Y

“…With a view to finding suitable methods for studying the antidepressive properties of the so-called atypical antidepressants we investigated the relationship…”
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