Search Results - "Avci, Hasan X"
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Astrocyte Differentiation of Human Pluripotent Stem Cells: New Tools for Neurological Disorder Research
Published in Frontiers in cellular neuroscience (26-09-2016)“…Astrocytes have a central role in brain development and function, and so have gained increasing attention over the past two decades. Consequently, our…”
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Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation
Published in Alzheimer's research & therapy (01-12-2017)“…Alzheimer's disease (AD) is the most common type of dementia, affecting one in eight adults over 65 years of age. The majority of AD cases are sporadic, with…”
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Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells
Published in Stem cell research (01-12-2017)“…Neural progenitor cells (NPCs) from human induced pluripotent stem cells (hiPSCs) are frequently induced using 3D culture methodologies however, it is unknown…”
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Bmi1 Loss in the Organ of Corti Results in p16ink4a Upregulation and Reduced Cell Proliferation of Otic Progenitors In Vitro
Published in PloS one (01-10-2016)“…The mature mammalian organ of Corti does not regenerate spontaneously after injury, mainly due to the absence of cell proliferation and the depletion of otic…”
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Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor α1 and krüppel-like factor 9 in Purkinje cells
Published in Proceedings of the National Academy of Sciences - PNAS (28-08-2012)“…Neurons in the CNS of higher vertebrates lose their ability to regenerate their axons at a stage of development that coincides with peak circulating thyroid…”
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Neurosphere Based Differentiation of Human iPSC Improves Astrocyte Differentiation
Published in Stem cells international (01-01-2016)“…Neural progenitor cells (NPCs) derived from human induced pluripotent stem cells (iPSCs) are traditionally maintained and proliferated utilizing…”
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The positional identity of iPSC-derived neural progenitor cells along the anterior-posterior axis is controlled in a dosage-dependent manner by bFGF and EGF
Published in Differentiation (London) (01-10-2016)“…Neural rosettes derived from human induced pluripotent stem cells (iPSCs) have been claimed to be a highly robust in vitro cellular model for biomedical…”
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The cell adhesion molecule NrCAM is crucial for growth cone behaviour and pathfinding of retinal ganglion cell axons
Published in Development (Cambridge) (01-08-2005)“…We investigated the role of the cell adhesion molecule NrCAM for axonal growth and pathfinding in the developing retina. Analysis of the distribution pattern…”
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Pax3 induces target-specific reinnervation through axon collateral expression of PSA-NCAM
Published in Progress in neurobiology (01-01-2024)“…Damaged or dysfunctional neural circuits can be replaced after a lesion by axon sprouting and collateral growth from undamaged neurons. Unfortunately, these…”
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In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities
Published in Archives of Toxicology. Archiv für Toxikologie (01-01-2017)“…Neurotoxicity and developmental neurotoxicity are important issues of chemical hazard assessment. Since the interpretation of animal data and their…”
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Journal Article Book Review -
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Mature Purkinje cells require the retinoic acid-related orphan receptor-α (RORα) to maintain climbing fiber mono-innervation and other adult characteristics
Published in The Journal of neuroscience (29-05-2013)“…Neuronal maturation during development is a multistep process regulated by transcription factors. The transcription factor RORα (retinoic acid-related orphan…”
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Thyroid hormone T3 triggers the developmental loss of axonal regenerative capacity
Published in M.S. Médecine sciences (01-03-2013)Get more information
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Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor alpha 1 and kruppel-like factor 9 in Purkinje cells
Published in Proceedings of the National Academy of Sciences - PNAS (28-08-2012)“…Neurons in the CNS of higher vertebrates lose their ability to regenerate their axons at a stage of development that coincides with peak circulating thyroid…”
Get full text
Journal Article -
14
Bmi1 Loss in the Organ of Corti Results in p16.sup.ink4a Upregulation and Reduced Cell Proliferation of Otic Progenitors In Vitro
Published in PloS one (18-10-2016)“…The mature mammalian organ of Corti does not regenerate spontaneously after injury, mainly due to the absence of cell proliferation and the depletion of otic…”
Get full text
Journal Article -
15
Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor [alpha]1 and krüppel-like factor 9 in Purkinje cells
Published in Proceedings of the National Academy of Sciences - PNAS (28-08-2012)“…Neurons in the CNS of higher vertebrates lose their ability to regenerate their axons at a stage of development that coincides with peak circulating thyroid…”
Get full text
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