Search Results - "Avanesyan, Lia"
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Immune evasion mediated by tumor-derived lactate dehydrogenase induction of NKG2D ligands on myeloid cells in glioblastoma patients
Published in Proceedings of the National Academy of Sciences - PNAS (02-09-2014)“…Myeloid cells are key regulators of the tumor microenvironment, governing local immune responses. Here we report that tumor-infiltrating myeloid cells and…”
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Acute Hepatitis C Virus Infection in Young Adult Injection Drug Users: A Prospective Study of Incident Infection, Resolution, and Reinfection
Published in The Journal of infectious diseases (15-10-2009)“…BackgroundHepatitis C virus (HCV) infection, clearance, and reinfection are best studied in injection drug users (IDUs), who have the highest incidence of HCV…”
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Cyclone: an accessible pipeline to analyze, evaluate, and optimize multiparametric cytometry data
Published in Frontiers in immunology (04-09-2023)“…In the past decade, high-dimensional single-cell technologies have revolutionized basic and translational immunology research and are now a key element of the…”
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Innate immunity and intestinal microbiota in the development of Type 1 diabetes
Published in Nature (23-10-2008)“…Type 1 diabetes (T1D) is a debilitating autoimmune disease that results from T-cell-mediated destruction of insulin-producing -cells. Its incidence has…”
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Cytotoxic Mechanisms Employed by Mouse T Cells to Destroy Pancreatic β-Cells
Published in Diabetes (New York, N.Y.) (01-11-2012)“…Several cytotoxic mechanisms have been attributed to T cells participating in β-cell death in type 1 diabetes. However, sensitivity of β-cells to these…”
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Cytotoxic mechanisms employed by mouse T cells to destroy pancreatic [beta]-cells
Published in Diabetes (New York, N.Y.) (01-11-2012)“…Several cytotoxic mechanisms have been attributed to T cells participating in [beta]-cell death in type 1 diabetes. However, sensitivity of [beta]-cells to…”
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Liver capsule: Age‐influenced hepatic immune priming determines HBV infection fate: Implications from mouse to man
Published in Hepatology (Baltimore, Md.) (01-01-2016)Get full text
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IL-21 is pivotal in determining age-dependent effectiveness of immune responses in a mouse model of human hepatitis B
Published in The Journal of clinical investigation (01-03-2011)“…HBV is a noncytopathic hepadnavirus and major human pathogen that causes immune-mediated acute and chronic hepatitis. The immune response to HBV antigens is…”
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Liver Capsule: AGE-INFLUENCED HEPATIC IMMUNE PRIMING DETERMINES HBV INFECTION FATE: IMPLICATIONS FROM MOUSE TO MAN
Published in Hepatology (Baltimore, Md.) (30-11-2015)Get full text
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S-3: Age-dependent hepatic lymphoid organization directs immune priming, cytokine production, and successful immunity to Hepatitis B virus
Published in Cytokine (Philadelphia, Pa.) (01-09-2013)“…Hepatitis B virus (HBV) is a non-cytopathic hepadnavirus and major human pathogen that causes immune-mediated acute and chronic hepatitis. The immune response…”
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