Search Results - "Avalle, Berangere"
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Molecularly Imprinted Polymer Nanoparticles as Potential Synthetic Antibodies for Immunoprotection against HIV
Published in ACS applied materials & interfaces (13-03-2019)“…We describe the preparation and characterization of synthetic antibodies based on molecularly imprinted polymer nanoparticles (MIP-NPs) for the recognition and…”
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Comparative Study of Single-stranded Oligonucleotides Secondary Structure Prediction Tools
Published in BMC bioinformatics (08-11-2023)“…Single-stranded nucleic acids (ssNAs) have important biological roles and a high biotechnological potential linked to their ability to bind to numerous…”
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AptaMat: a matrix-based algorithm to compare single-stranded oligonucleotides secondary structures
Published in Bioinformatics (Oxford, England) (01-01-2023)“…Abstract Motivation Comparing single-stranded nucleic acids (ssNAs) secondary structures is fundamental when investigating their function and evolution and…”
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4
Anti-Idiotypic Antibody Mimics Proteolytic Function of Parent Antigen
Published in Biochemistry (Easton) (18-12-2007)“…Functional imaging of subtilisin Carlsberg active center by the idiotypic network yielded a catalytic anti-idiotypic antibody with endopeptidase, amidase, and…”
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5
Lyme borreliosis diagnosis: state of the art of improvements and innovations
Published in BMC microbiology (01-08-2023)“…With almost 700 000 estimated cases each year in the United States and Europe, Lyme borreliosis (LB), also called Lyme disease, is the most common tick-borne…”
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Production, purification, and quality assessment of borrelial proteins CspZ from Borrelia burgdorferi and FhbA from Borrelia hermsii
Published in Applied microbiology and biotechnology (01-12-2024)“…Borrelia , spirochetes transmitted by ticks, are the etiological agents of numerous multisystemic diseases, such as Lyme borreliosis (LB) and tick-borne…”
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Genetic background and immunological status influence B cell repertoire diversity in mice
Published in Scientific reports (03-10-2019)“…The relationship between the immune repertoire and the physiopathological status of individuals is essential to apprehend the genesis and the evolution of…”
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Reactibodies generated by kinetic selection couple chemical reactivity with favorable protein dynamics
Published in Proceedings of the National Academy of Sciences - PNAS (20-09-2011)“…Igs offer a versatile template for combinatorial and rational design approaches to the de novo creation of catalytically active proteins. We have used a…”
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Recognition and Degradation of Myelin Basic Protein Peptides by Serum Autoantibodies: Novel Biomarker for Multiple Sclerosis
Published in The Journal of immunology (1950) (15-01-2008)“…The pathologic role of autoantibodies in autoimmune disease is widely accepted. Recently, we reported that anti-myelin basic protein (MBP) serum Abs from…”
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Structural and Functional Mise en Abyme
Published in Frontiers in molecular biosciences (28-11-2019)Get full text
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Combinatorial antibody library from multiple sclerosis patients reveals antibodies that cross‐react with myelin basic protein and EBV antigen
Published in The FASEB journal (01-12-2011)“…ABSTRACT Multiple sclerosis (MS) is a widespread neurodegenerative autoimmune disease with unknown etiology. It is increasingly evident that, together with…”
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Multitarget selection of catalytic antibodies with β‐lactamase activity using phage display
Published in The FEBS journal (01-02-2017)“…β‐lactamase enzymes responsible for bacterial resistance to antibiotics are among the most important health threats to the human population today…”
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Exploitation of rolling circle amplification for the construction of large phage-display antibody libraries
Published in Journal of immunological methods (01-05-2014)“…Phage display antibody libraries have proven to have a significant role in the discovery of therapeutic antibodies and polypeptides with desired biological and…”
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Catalytic antibodies and their applications in biotechnology: state of the art
Published in Biotechnology letters (01-07-2014)“…Catalytic antibodies are immunoglobulins endowed with enzymatic properties. Discovered in the second part of the 1980s, the enthusiasm they initially aroused…”
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Autoantibodies to Myelin Basic Protein Catalyze Site-Specific Degradation of Their Antigen
Published in Proceedings of the National Academy of Sciences - PNAS (10-01-2006)“…Autoantibody-mediated tissue destruction is among the main features of organ-specific autoimmunity. This report describes "an antibody enzyme" (abzyme)…”
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Efficient refolding of a recombinant abzyme: Structural and catalytic characterizations
Published in Applied microbiology and biotechnology (01-09-2013)“…Catalytic antibodies are currently being investigated in order to understand their role under physio-pathological situations. To this end, the knowledge of…”
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Mutational and inhibitory analysis of a catalytic antibody. Implication for drug discovery
Published in Molecular immunology (01-12-2009)“…Data on catalytic antibodies (abzymes) having critical roles in pathologies, for example in some auto-immune diseases accumulate at overwhelming pace…”
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A novel molecular analysis of genes encoding catalytic antibodies
Published in Molecular immunology (01-03-2012)“…► We analyze the somatic hypermutations of catalytic antibodies displaying an amidase activity by comparison to the closest germline genes using the IMGT…”
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Enzyme Mimicry by the Antiidiotypic Antibody Approach
Published in Proceedings of the National Academy of Sciences - PNAS (05-12-2000)“…The concept of "internal image" of antiidiotypic antibodies has provided the basis for eliciting catalytic antibodies. A monoclonal IgM 9A8 that was obtained…”
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Novel peptide inhibiting both TEM‐1 β‐lactamase and penicillin‐binding proteins
Published in The FEBS journal (01-12-2010)“…9G4H9, a catalytic antibody displaying β‐lactamase‐like activity, has been developed by the anti‐idiotypic approach using β‐lactamase as the first antigen…”
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