Search Results - "Autoimmunity (Chur, Switzerland)"

Th1, Th2, and Th17 cytokines in systemic lupus erythematosus by Muhammad Yusoff, Farhana, Wong, Kah Keng, Mohd Redzwan, Norhanani

“…Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the breakdown of immune tolerance leading to excessive inflammation and tissue…”
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Recent advances of exosomes in immune modulation and autoimmune diseases by Tan, Lina, Wu, Haijing, Liu, Ying, Zhao, Ming, Li, Duo, Lu, Qianjin

“…Exosomes are small membrane-bound vesicles (30-100 nm) that are secreted by different types of cells and they have been well documented to resemble saucers or…”
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The role of NLRP3 inflammasome in type 2 inflammation related diseases by Xu, Shenming, Wang, Dan, Tan, Lina, Lu, Jianyun

“…Type 2 inflammation related diseases, such as atopic dermatitis, asthma, and allergic rhinitis, are diverse and affect multiple systems in the human body. It…”
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Quercetin improves the imbalance of Th1/Th2 cells and Treg/Th17 cells to attenuate allergic rhinitis by Ke, Xia, Chen, Ziqi, Wang, Xiaoqiang, Kang, Houyong, Hong, Suling

“…Allergic rhinitis (AR) is a common inflammation that affects many people globally. Quercetin has anti-allergic biological activity in AR. Here, we aimed to…”
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Icariin alleviates rheumatoid arthritis via regulating miR-223-3p/NLRP3 signalling axis by Wu, Zhi-Ming, Luo, Jun, Shi, Xiao-Dong, Zhang, Shao-Xin, Zhu, Xiao-Bo, Guo, Jian

“…Rheumatoid arthritis (RA) is considered to be a chronic autoimmune disease, pathogenesis of RA is complex and effective treatments for RA is still lacking…”
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The role of NLRP3 inflammasome in the pathogenesis of rheumatic disease by Kong, Ruixue, Sun, Lulu, Li, Hua, Wang, Dashan

“…Inflammasome is a molecular platform that is formed in the cytosolic compartment to mediate host immune responses to infection and cellular damage…”
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LncRNA GAS5 alleviates rheumatoid arthritis through regulating miR-222-3p/Sirt1 signalling axis by Yang, Zhou, Lin, Shu-Dian, Zhan, Feng, Liu, Ying, Zhan, Yu-Wei

“…Rheumatoid arthritis (RA) is an autoimmune disease that affects millions of people. Fibroblast-like synoviocytes (FLSs) located in rheumatoid panni play a…”
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Role of oxidative stress in pathophysiology of rheumatoid arthritis: insights into NRF2-KEAP1 signalling by Kaur, Gurjasmine, Sharma, Aman, Bhatnagar, Archana

“…Rheumatoid arthritis is one of the most prevalent, chronic, inflammatory disorders involving multiple articular and extra-articular complications. Immune…”
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Clonally expanded cytotoxic CD4+ T cells and the pathogenesis of IgG4-related disease by Mattoo, Hamid, Stone, John H., Pillai, Shiv

“…IgG4-related disease (IgG4-RD) is a systemic condition of unknown cause characterized by highly fibrotic lesions, with dense lymphoplasmacytic infiltrates…”
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Disease-related autoantibody profile in patients with systemic sclerosis by Liaskos, Christos, Marou, Emmanouela, Simopoulou, Theodora, Barmakoudi, Maria, Efthymiou, Georgios, Scheper, Thomas, Meyer, Wolfgang, Bogdanos, Dimitrios P., Sakkas, Lazaros I.

“…Background: Autoantibodies (autoAbs) help in diagnosis and predicting clinical phenotypes in systemic sclerosis (SSc). Aim of the study: To determine the…”
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Immunoregulatory effects of indole-3-carbinol on monocyte-derived macrophages in systemic lupus erythematosus: A crucial role for aryl hydrocarbon receptor by Mohammadi, Saeed, Memarian, Ali, Sedighi, Sima, Behnampour, Nasser, Yazdani, Yaghoub

“…Macrophages are versatile phagocytic cells in immune system with immunoregulatory functions. However, the removal of apoptotic cells by macrophages is…”
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LncRNA OIP5-AS1/miR-410-3p/Wnt7b axis promotes the proliferation of rheumatoid arthritis fibroblast-like synoviocytes via regulating the Wnt/β-catenin pathway by Sun, Yuan, Jiang, Hui, Pan, LingYu, Han, YanQuan, Chen, Yan, Jiang, Yeke, Wang, Yongzhong

“…LncRNA OIP5-AS1 has a common gene imbalance in various cancers and tumours, which plays an important role in regulating its biological function. However, there…”
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COVID-19: captures iron and generates reactive oxygen species to damage the human immune system by Wenzhong, Liu, Hualan, Li

“…Currently, the novel coronavirus pneumonia has been widespread globally, and there is no specific medicine. In response to the emergency, we employed…”
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New insights into the role of T cells in pathogenesis of psoriasis and psoriatic arthritis by Karczewski, Jacek, Dobrowolska, Agnieszka, Rychlewska-Hańczewska, Anna, Adamski, Zygmunt

“…Psoriasis is a chronic, relapsing, autoimmune disorder of the skin affecting 2-3% of general population. Approximately 30% of psoriasis patients are also…”
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Animal models of lupus nephritis: the past, present and a future outlook by Katikaneni, Divya, Morel, Laurence, Scindia, Yogesh

“…Lupus nephritis (LN) is the most severe end-organ pathology in Systemic Lupus Erythematosus (SLE). Research has enhanced our understanding of immune effectors…”
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Identification of macrophage-related molecular subgroups and risk signature in colorectal cancer based on a bioinformatics analysis by Liu, Qi, Liao, Li

“…Macrophages play a crucial role in tumor initiation and progression, while macrophage-associated gene signature in colorectal cancer (CRC) patients has not…”
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Macrophages in vascular inflammation - From atherosclerosis to vasculitis by Shirai, Tsuyoshi, Hilhorst, Marc, Harrison, David G., Goronzy, Jörg J., Weyand, Cornelia M.

“…Abstract The spectrum of vascular inflammatory disease ranges from atherosclerosis and hypertension, widespread conditions affecting large proportions of the…”
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Individual and stable autoantibody repertoires in healthy individuals by Neiman, Maja, Hellström, Cecilia, Just, David, Mattsson, Cecilia, Fagerberg, Linn, Schuppe-Koistinen, Ina, Gummesson, Anders, Bergström, Göran, Kallioniemi, Olli, Achour, Adnane, Sallinen, Riitta, Uhlén, Mathias, Nilsson, Peter

“…In the era towards precision medicine, we here present the individual specific autoantibody signatures of 193 healthy individuals. The self-reactive IgG…”
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Effect of therapeutic plasma exchange on immunoglobulins in myasthenia gravis by Guptill, Jeffrey T., Juel, Vern C., Massey, Janice M., Anderson, Amanda C., Chopra, Manisha, Yi, John S., Esfandiari, Ehsanollah, Buchanan, Tim, Smith, Bryan, Atherfold, Paul, Jones, Emma, Howard, James F.

“…An integrated understanding of therapeutic plasma exchange (TPE) effects on immunoglobulins, autoantibodies, and natural or acquired (vaccine) protective…”
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The onset of de novo autoantibodies in healthcare workers after mRNA based anti-SARS-CoV-2 vaccines: a single centre prospective follow-up study by Sacchi, M.C, Pelazza, C., Bertolotti, M., Agatea, L., De Gaspari, P., Tamiazzo, S., Ielo, D., Stobbione, P., Grappiolo, M., Bolgeo, T., Novel, P., Ciriello, M.M, Maconi, A.

“…Nowadays, data concerning the risk of autoimmune disease after SARS-CoV-2 (COVID-19) vaccination is controversial. The aim of this single centre prospective…”
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