Search Results - "Autio, A"

High-risk prostate cancer—classification and therapy by Chang, Albert J., Autio, Karen A., Roach, Mack, Scher, Howard I.

“…Key Points Patients with high-risk prostate cancer have a significant chance of developing systemic or local recurrence, and are at higher risk for symptoms…”
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The nonhuman primate neuroimaging and neuroanatomy project by Hayashi, Takuya, Hou, Yujie, Glasser, Matthew F, Autio, Joonas A, Knoblauch, Kenneth, Inoue-Murayama, Miho, Coalson, Tim, Yacoub, Essa, Smith, Stephen, Kennedy, Henry, Van Essen, David C

“…Multi-modal neuroimaging projects such as the Human Connectome Project (HCP) and UK Biobank are advancing our understanding of human brain architecture,…”
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Comparative connectomics of the primate social brain by Yokoyama, Chihiro, Autio, Joonas A., Ikeda, Takuro, Sallet, Jérôme, Mars, Rogier B., Van Essen, David C., Glasser, Matthew F., Sadato, Norihiro, Hayashi, Takuya

“…•Advances in primate neuroimaging enable comparative connectomics.•The number of cortical neurons and size of social group are associated in non-human…”
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Towards HCP-Style macaque connectomes: 24-Channel 3T multi-array coil, MRI sequences and preprocessing by Autio, Joonas A., Glasser, Matthew F., Ose, Takayuki, Donahue, Chad J., Bastiani, Matteo, Ohno, Masahiro, Kawabata, Yoshihiko, Urushibata, Yuta, Murata, Katsutoshi, Nishigori, Kantaro, Yamaguchi, Masataka, Hori, Yuki, Yoshida, Atsushi, Go, Yasuhiro, Coalson, Timothy S., Jbabdi, Saad, Sotiropoulos, Stamatios N., Kennedy, Henry, Smith, Stephen, Van Essen, David C., Hayashi, Takuya

“…Macaque monkeys are an important animal model where invasive investigations can lead to a better understanding of the cortical organization of primates…”
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What conditions favor the influence of seasonally frozen ground on hydrological partitioning? A systematic review by Ala-Aho, P, Autio, A, Bhattacharjee, J, Isokangas, E, Kujala, K, Marttila, H, Menberu, M, Meriö, L-J, Postila, H, Rauhala, A, Ronkanen, A-K, Rossi, P M, Saari, M, Haghighi, A Torabi, Kløve, B

“…Abstract The influence of seasonally frozen ground (SFG) on water, energy, and solute fluxes is important in cold climate regions. The hydrological role of…”
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Empirical transmit field bias correction of T1w/T2w myelin maps by Glasser, Matthew F., Coalson, Timothy S., Harms, Michael P., Xu, Junqian, Baum, Graham L., Autio, Joonas A., Auerbach, Edward J., Greve, Douglas N., Yacoub, Essa, Van Essen, David C., Bock, Nicholas A., Hayashi, Takuya

“…T1-weighted divided by T2-weighted (T1w/T2w) myelin maps were initially developed for neuroanatomical analyses such as identifying cortical areas, but they are…”
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Targeting the androgen receptor in prostate and breast cancer: several new agents in development by Proverbs-Singh, Tracy, Feldman, Jarett L, Morris, Michael J, Autio, Karen A, Traina, Tiffany A

“…Prostate cancer (PCa) and breast cancer (BCa) share similarities as hormone-sensitive cancers with a wide heterogeneity of both phenotype and biology. The…”
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Minimal specifications for non-human primate MRI: Challenges in standardizing and harmonizing data collection by Autio, Joonas A., Zhu, Qi, Li, Xiaolian, Glasser, Matthew F., Schwiedrzik, Caspar M., Fair, Damien A., Zimmermann, Jan, Yacoub, Essa, Menon, Ravi S., Van Essen, David C., Hayashi, Takuya, Russ, Brian, Vanduffel, Wim

“…•Non-human primate MRI standardization.•Poor reproducibility in non-human primate resting-state fMRI.•Guidelines enable improved and more reproducible MRI…”
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Anatomical variability, multi-modal coordinate systems, and precision targeting in the marmoset brain by Ose, Takayuki, Autio, Joonas A., Ohno, Masahiro, Frey, Stephen, Uematsu, Akiko, Kawasaki, Akihiro, Takeda, Chiho, Hori, Yuki, Nishigori, Kantaro, Nakako, Tomokazu, Yokoyama, Chihiro, Nagata, Hidetaka, Yamamori, Tetsuo, Van Essen, David C., Glasser, Matthew F., Watabe, Hiroshi, Hayashi, Takuya

“…•Achieved sub-millimeter localization accuracy of subject-wise brain region.•Propose a dedicated non-invasive multi-modal subject-specific registration…”
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Cortical adaptation of the night monkey to a nocturnal niche environment: a comparative non-invasive T1w/T2w myelin study by Ikeda, Takuro, Autio, Joonas A., Kawasaki, Akihiro, Takeda, Chiho, Ose, Takayuki, Takada, Masahiko, Van Essen, David C., Glasser, Matthew F., Hayashi, Takuya

“…Night monkeys ( Aotus ) are the only genus of monkeys within the Simian lineage that successfully occupy a nocturnal environmental niche. Their behavior is…”
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Magnetotelluric array in the central Finnish Lapland I: Extreme data characteristics by Autio, U.A., Smirnov, M.Yu

“…We present magnetotelluric (MT) data from the northern Fennoscandian shield, which show extreme behavior due to the complex geoelectric setting left behind by…”
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High b-value diffusion-weighted fMRI in a rat forepaw electrostimulation model at 7 T by Autio, Joonas A A, Kershaw, Jeff, Shibata, Sayaka, Obata, Takayuki, Kanno, Iwao, Aoki, Ichio

“…Spin-echo diffusion-weighted functional MRI (DW-fMRI) was performed on a rat forepaw electrostimulation model at 7 T. This small animal model used electric…”
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CX-072 (pacmilimab), a Probody® PD-L1 inhibitor, in advanced or recurrent solid tumors (PROCLAIM-CX-072): an open-label dose-finding and first-in-human study by Naing, Aung, Thistlethwaite, Fiona, De Vries, Elisabeth G.E., Eskens, Ferry A.L.M., Uboha, Nataliya, Ott, Patrick A., LoRusso, Patricia, Garcia-Corbacho, Javier, Boni, Valentina, Bendell, Johanna, Autio, Karen A., Randhawa, Manreet, Durm, Greg, Gil-Martin, Marta, Stroh, Mark, Hannah, Alison L., Arkenau, Hendrik-Tobias, Spira, Alexander

“…BackgroundProbody® therapeutics are antibody prodrugs that are activated in the tumor microenvironment by tumor-associated proteases, thereby restricting the…”
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Analysis of the Prevalence of Microsatellite Instability in Prostate Cancer and Response to Immune Checkpoint Blockade by Abida, Wassim, Cheng, Michael L, Armenia, Joshua, Middha, Sumit, Autio, Karen A, Vargas, Hebert Alberto, Rathkopf, Dana, Morris, Michael J, Danila, Daniel C, Slovin, Susan F, Carbone, Emily, Barnett, Ethan S, Hullings, Melanie, Hechtman, Jaclyn F, Zehir, Ahmet, Shia, Jinru, Jonsson, Philip, Stadler, Zsofia K, Srinivasan, Preethi, Laudone, Vincent P, Reuter, Victor, Wolchok, Jedd D, Socci, Nicholas D, Taylor, Barry S, Berger, Michael F, Kantoff, Philip W, Sawyers, Charles L, Schultz, Nikolaus, Solit, David B, Gopalan, Anuradha, Scher, Howard I

“…The anti-programmed cell death protein 1 (PD-1) antibody pembrolizumab is approved by the US Food and Drug Administration for the treatment of microsatellite…”
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CX-072 (pacmilimab), a Probody PD-L1 inhibitor, in combination with ipilimumab in patients with advanced solid tumors (PROCLAIM-CX-072): a first-in-human, dose-finding study by Sanborn, Rachel E, Hamid, Omid, de Vries, Elisabeth GE, Ott, Patrick A, Garcia-Corbacho, Javier, Boni, Valentina, Bendell, Johanna, Autio, Karen A, Cho, Daniel C, Plummer, Ruth, Stroh, Mark, Lu, Lawrence, Thistlethwaite, Fiona

“…BackgroundProbody® therapeutics are antibody prodrugs designed to be activated by tumor-associated proteases. This conditional activation restricts antibody…”
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Probody Therapeutics: An Emerging Class of Therapies Designed to Enhance On-Target Effects with Reduced Off-Tumor Toxicity for Use in Immuno-Oncology by Autio, Karen A, Boni, Valentina, Humphrey, Rachel W, Naing, Aung

“…The deep and durable antitumor effects of antibody-based immunotherapies such as immune checkpoint inhibitors (ICIs) have revolutionized oncology and…”
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Pain palliation measurement in cancer clinical trials: The US Food and Drug Administration perspective by Basch, Ethan, Trentacosti, Ann Marie, Burke, Laurie B., Kwitkowski, Virginia, Kane, Robert C., Autio, Karen A., Papadopoulos, Elektra, Stansbury, James P., Kluetz, Paul G., Smith, Harry, Justice, Robert, Pazdur, Richard

“…BACKGROUND Pain palliation resulting from antitumor therapy provides direct evidence of treatment benefit when combined with evidence of antitumor activity…”
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First-in-human, phase 1 study of PF-06753512, a vaccine-based immunotherapy regimen (VBIR), in non-metastatic hormone-sensitive biochemical recurrence and metastatic castration-resistant prostate cancer (mCRPC) by Autio, Karen A, Higano, Celestia S, Nordquist, Luke, Appleman, Leonard J, Zhang, Tian, Zhu, Xin-Hua, Babiker, Hani, Vogelzang, Nicholas J, Prasad, Sandip M, Schweizer, Michael T, Madan, Ravi A, Billotte, Stephane, Cavazos, Nora, Bogg, Orlaith, Li, Ray, Chan, Kam, Cho, Helen, Kaneda, Megan, Wang, I-Ming, Zheng, Jenny, Tang, Szu-Yu, Hollingsworth, Robert, Kern, Kenneth A, Petrylak, Daniel P

“…BackgroundThis phase 1 study evaluated PF-06753512, a vaccine-based immunotherapy regimen (PrCa VBIR), in two clinical states of prostate cancer (PC),…”
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First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1) by Postel-Vinay, Sophie, Lam, Vincent K, Ros, Willeke, Bauer, Todd M, Hansen, Aaron R, Cho, Daniel C, Stephen Hodi, F, Schellens, Jan H M, Litton, Jennifer K, Aspeslagh, Sandrine, Autio, Karen A, Opdam, Frans L, McKean, Meredith, Somaiah, Neeta, Champiat, Stephane, Altan, Mehmet, Spreafico, Anna, Rahma, Osama, Paul, Elaine M, Ahlers, Christoph M, Zhou, Helen, Struemper, Herbert, Gorman, Shelby A, Watmuff, Maura, Yablonski, Kaitlin M, Yanamandra, Niranjan, Chisamore, Michael J, Schmidt, Emmett V, Hoos, Axel, Marabelle, Aurelien, Weber, Jeffrey S, Heymach, John V

“…BackgroundThe phase I first-in-human study ENGAGE-1 evaluated the humanized IgG1 OX40 agonistic monoclonal antibody GSK3174998 alone (Part 1 (P1)) or in…”
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Determinants of spontaneous resorption of intervertebral disc herniations by AUTIO, Reijo A, KARPPINEN, Jaro, NIINIMAKI, Jaakko, OJALA, Risto, KURUNLAHTI, Mauno, HAAPEA, Marianne, VANHARANTA, Heikki, TERVONEN, Osmo

“…A follow-up of disc herniation (herniated nucleus pulposus [HNP]) resorption on magnetic resonance imaging (MRI). To assess the determinants of resorption of…”
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