Search Results - "Authier, Francois Jerome"
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Myalgia and chronic fatigue syndrome following immunization: macrophagic myofasciitis and animal studies support linkage to aluminum adjuvant persistency and diffusion in the immune system
Published in Autoimmunity reviews (01-07-2019)“…Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a multifactorial and poorly undersood disabling disease. We present epidemiological, clinical…”
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Necroptosis mediates myofibre death in dystrophin-deficient mice
Published in Nature communications (07-09-2018)“…Duchenne muscular dystrophy (DMD) is a severe degenerative disorder caused by mutations in the dystrophin gene. Dystrophin-deficient muscles are characterised…”
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Idiopathic eosinophilic myositis: a systematic literature review
Published in Neuromuscular disorders : NMD (01-02-2022)“…•Eosinophilic myositis are defined by a muscle eosinophilic infiltrate.•Eosinophilic myositis are divided in subtypes according to the histological…”
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JAK inhibitors are effective in a subset of patients with juvenile dermatomyositis: a monocentric retrospective study
Published in Rheumatology (01-12-2021)“…Abstract Objective To evaluate the efficacy and safety of Janus kinase inhibitors (JAKis) in JDM. Methods We conducted a single-centre retrospective study of…”
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Muscle ischaemia associated with NXP2 autoantibodies: a severe subtype of juvenile dermatomyositis
Published in Rheumatology (Oxford, England) (01-05-2018)“…Abstract Objectives Myositis-specific autoantibodies (MSAs) are increasingly used to delineate distinct subgroups of JDM. The aim of our study was to explore…”
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Muscle satellite cells and endothelial cells: close neighbors and privileged partners
Published in Molecular biology of the cell (01-04-2007)“…Genetically engineered mice (Myf5nLacZ/+, Myf5GFP-P/+) allowing direct muscle satellite cell (SC) visualization indicate that, in addition to being located…”
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Critical analysis of reference studies on the toxicokinetics of aluminum-based adjuvants
Published in Journal of inorganic biochemistry (01-04-2018)“…We reviewed the three toxicokinetic reference studies commonly used to suggest that aluminum (Al)-based adjuvants are innocuous. A single experimental study…”
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Non-linear dose-response of aluminium hydroxide adjuvant particles: selective low dose neurotoxicity
Published in Toxicology (Amsterdam) (15-01-2017)“…Abstract Aluminium (Al) oxyhydroxide (Alhydrogel® ), the main adjuvant licensed for human and animal vaccines, consists of primary nanoparticles that…”
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Receptor interacting protein kinase‐3 mediates both myopathy and cardiomyopathy in preclinical animal models of Duchenne muscular dystrophy
Published in Journal of cachexia, sarcopenia and muscle (01-12-2023)“…Background Duchenne muscular dystrophy (DMD) is a progressive muscle degenerative disorder, culminating in a complete loss of ambulation, hypertrophic…”
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Thyroid-stimulating hormone receptor signaling restores skeletal muscle stem cell regeneration in rats with muscular dystrophy
Published in Science translational medicine (01-03-2023)“…Duchenne muscular dystrophy (DMD) is a severe and progressive myopathy leading to motor and cardiorespiratory impairment. We analyzed samples from patients…”
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Autocrine and Paracrine Angiopoietin 1/Tie-2 Signaling Promotes Muscle Satellite Cell Self-Renewal
Published in Cell stem cell (04-09-2009)“…Mechanisms governing muscle satellite cell withdrawal from cell cycle to enter into quiescence remain poorly understood. We studied the role of angiopoietin 1…”
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Hemifacial myohyperplasia is due to somatic muscular PIK3CA gain-of-function mutations and responds to pharmacological inhibition
Published in The Journal of experimental medicine (06-11-2023)“…Hemifacial myohyperplasia (HFMH) is a rare cause of facial asymmetry exclusively involving facial muscles. The underlying cause and the mechanism of disease…”
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Clinical impact of dual-tracer FDOPA and FDG PET/CT for the evaluation of patients with parkinsonian syndromes
Published in Medicine (Baltimore) (06-11-2020)“…Parkinsonian syndromes include typical cases of idiopathic Parkinson's disease (PD) and atypical parkinsonian syndromes (APS) associated with cognitive and…”
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Anti-SAE autoantibody in dermatomyositis: original comparative study and review of the literature
Published in Rheumatology (01-12-2023)“…Abstract Objective Among specific autoantibodies in DM, the anti–small ubiquitin-like modifier activating enzyme (SAE) antibody is rare. We aim to describe the…”
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Loss of phospholipase PLAAT3 causes a mixed lipodystrophic and neurological syndrome due to impaired PPARγ signaling
Published in Nature genetics (01-11-2023)“…Phospholipase A/acyltransferase 3 (PLAAT3) is a phospholipid-modifying enzyme predominantly expressed in neural and white adipose tissue (WAT). It is a…”
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Efficacy and tolerance of corticosteroids and methotrexate in patients with juvenile dermatomyositis: a retrospective cohort study
Published in Rheumatology (Oxford, England) (02-11-2022)“…To assess the efficacy and tolerance of the conventional first-line treatment by methotrexate (MTX) and corticosteroids (CS) in patients with juvenile…”
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The role of aluminum adjuvants in vaccines raises issues that deserve independent, rigorous and honest science
Published in Journal of trace elements in medicine and biology (01-12-2020)Get full text
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Slow CCL2-dependent translocation of biopersistent particles from muscle to brain
Published in BMC medicine (04-04-2013)“…Long-term biodistribution of nanomaterials used in medicine is largely unknown. This is the case for alum, the most widely used vaccine adjuvant, which is a…”
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Myopathologic trajectory in Duchenne muscular dystrophy (DMD) reveals lack of regeneration due to senescence in satellite cells
Published in Acta neuropathologica communications (19-10-2023)“…Duchenne muscular dystrophy (DMD) is a devastating X-linked muscular disease, caused by mutations in the DMD gene encoding Dystrophin and affecting 1:5000 boys…”
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An early onset benign myopathy with glycogen storage caused by a de novo 1.4 Mb-deletion of chromosome 14
Published in Neuromuscular disorders : NMD (01-10-2023)Get full text
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