Search Results - "Autenrieth, Ingo B"
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Structure and function: Lipid A modifications in commensals and pathogens
Published in International journal of medical microbiology (01-08-2016)“…Abstract Lipopolysaccharides (LPS) of Gram negative bacteria are one of the most potent stimulators of the host innate immune system and LPS recognition is…”
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Distinct impact of antibiotics on the gut microbiome and resistome: a longitudinal multicenter cohort study
Published in BMC biology (18-09-2019)“…The selection pressure exercised by antibiotic drugs is an important consideration for the wise stewardship of antimicrobial treatment programs. Treatment…”
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Fourier-Transform Infrared (FTIR) Spectroscopy for Typing of Clinical Enterobacter cloacae Complex Isolates
Published in Frontiers in microbiology (06-11-2019)“…Members of the Enterobacter ( E. ) cloacae complex have emerged as important pathogens frequently encountered in nosocomial infections. Several outbreaks with…”
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A nasal epithelial receptor for Staphylococcus aureus WTA governs adhesion to epithelial cells and modulates nasal colonization
Published in PLoS pathogens (01-05-2014)“…Nasal colonization is a major risk factor for S. aureus infections. The mechanisms responsible for colonization are still not well understood and involve…”
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Antibiotic Selection Pressure Determination through Sequence-Based Metagenomics
Published in Antimicrobial agents and chemotherapy (01-12-2015)“…The human gut forms a dynamic reservoir of antibiotic resistance genes (ARGs). Treatment with antimicrobial agents has a significant impact on the intestinal…”
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Analysis of a long-term outbreak of XDR Pseudomonas aeruginosa: a molecular epidemiological study
Published in Journal of antimicrobial chemotherapy (01-05-2015)“…Here we report on a long-term outbreak from 2009 to 2012 with an XDR Pseudomonas aeruginosa on two wards at a university hospital in southern Germany…”
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The Inverse Autotransporter Intimin Exports Its Passenger Domain via a Hairpin Intermediate
Published in The Journal of biological chemistry (16-01-2015)“…Autotransporter proteins comprise a large family of virulence factors that consist of a β-barrel translocation unit and an extracellular effector or passenger…”
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Deprivation of the Periplasmic Chaperone SurA Reduces Virulence and Restores Antibiotic Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa
Published in Frontiers in microbiology (2019)“…is one of the main causative agents of nosocomial infections and the spread of multidrug-resistant strains is rising. Therefore, novel strategies for therapy…”
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Plasmacytoid dendritic cells are crucial in Bifidobacterium adolescentis-mediated inhibition of Yersinia enterocolitica infection
Published in PloS one (20-08-2013)“…In industrialized countries bacterial intestinal infections are commonly caused by enteropathogenic Enterobacteriaceae. The interaction of the microbiota with…”
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Molecular Evolution of Extensively Drug-Resistant (XDR) Pseudomonas aeruginosa Strains From Patients and Hospital Environment in a Prolonged Outbreak
Published in Frontiers in microbiology (08-08-2019)“…In this study, we aimed to elucidate a prolonged outbreak of extensively drug-resistant (XDR) , at two adjacent hospitals over a time course of 4 years. Since…”
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11
The Intimin periplasmic domain mediates dimerisation and binding to peptidoglycan
Published in Molecular microbiology (01-01-2015)“…Summary Intimin and Invasin are prototypical inverse (Type Ve) autotransporters and important virulence factors of enteropathogenic Escherichia coli and…”
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Intimin and invasin export their C-terminus to the bacterial cell surface using an inverse mechanism compared to classical autotransport
Published in PloS one (09-10-2012)“…Invasin and intimin are major virulence factors of enteropathogenic Yersiniae and Escherichia coli, mediating invasion into and intimate adherence to host…”
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Apoptotic Cells Induce Migration of Phagocytes via Caspase-3-Mediated Release of a Lipid Attraction Signal
Published in Cell (13-06-2003)“…Efficient engulfment of the intact cell corpse is a critical end point of apoptosis, required to prevent secondary necrosis and inflammation. The presentation…”
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14
Lipopolysaccharide induces cell volume increase and migration of dendritic cells
Published in Microbiology and immunology (01-01-2014)“…ABSTRACT Migration of dendritic cells (DCs) plays an important role in T‐cell‐mediated adaptive immune responses. Lipopolysaccharide (LPS) sensed by Toll‐like…”
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Detection of pneumonia associated pathogens using a prototype multiplexed pneumonia test in hospitalized patients with severe pneumonia
Published in PloS one (14-11-2014)“…Severe pneumonia remains an important cause of morbidity and mortality. Polymerase chain reaction (PCR) has been shown to be more sensitive than current…”
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Time Series Analysis as a Tool To Predict the Impact of Antimicrobial Restriction in Antibiotic Stewardship Programs Using the Example of Multidrug-Resistant Pseudomonas aeruginosa
Published in Antimicrobial Agents and Chemotherapy (01-04-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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BamA and BamD Are Essential for the Secretion of Trimeric Autotransporter Adhesins
Published in Frontiers in microbiology (23-02-2021)“…The BAM complex in is composed of five proteins, BamA-E. BamA and BamD are essential for cell viability and are required for the assembly of β-barrel outer…”
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A Computational Model of Bacterial Population Dynamics in Gastrointestinal Yersinia enterocolitica Infections in Mice
Published in Biology (Basel, Switzerland) (12-02-2022)“…The complex interplay of a pathogen with its virulence and fitness factors, the host's immune response, and the endogenous microbiome determine the course and…”
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The Positron Emission Tomography Tracer 3'-Deoxy-3'-[18F]Fluorothymidine ([18F]FLT) Is Not Suitable to Detect Tissue Proliferation Induced by Systemic Yersinia enterocolitica Infection in Mice
Published in PloS one (04-10-2016)“…Most frequently, gram-negative bacterial infections in humans are caused by Enterobacteriaceae and remain a major challenge in medical diagnostics. We…”
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Development of a DNA Microarray for Detection and Identification of Fungal Pathogens Involved in Invasive Mycoses
Published in Journal of Clinical Microbiology (01-10-2005)“…Invasive fungal infections have emerged as a major cause of morbidity and mortality in immunocompromised patients. Conventional identification of pathogenic…”
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