Search Results - "Autelli, Riccardo"

PPARγ antagonism as a new tool for preventing or overcoming endocrine resistance in luminal A breast cancers by Boretto, Cecilia, Muzio, Giuliana, Autelli, Riccardo

“…This research investigates the role of PPARγ in the complex molecular events underlying the acquisition of resistance to tamoxifen (Tam) in luminal A breast…”
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Bridging Discoveries and Treatments: The New Landscape of Breast Cancer Research by Hu, Taobo, Wang, Lei, Autelli, Riccardo, Long, Mengping

“…Welcome to our Special Issue, "Advances in Breast Cancer Research and Treatment" of , where we have embarked on a comprehensive exploration of groundbreaking…”
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Tamoxifen Activates Transcription Factor EB and Triggers Protective Autophagy in Breast Cancer Cells by Inducing Lysosomal Calcium Release: A Gateway to the Onset of Endocrine Resistance by Boretto, Cecilia, Actis, Chiara, Faris, Pawan, Cordero, Francesca, Beccuti, Marco, Ferrero, Giulio, Muzio, Giuliana, Moccia, Francesco, Autelli, Riccardo

“…Among the several mechanisms accounting for endocrine resistance in breast cancer, autophagy has emerged as an important player. Previous reports have…”
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Expression of Cox-2 in human breast cancer cells as a critical determinant of epithelial-to-mesenchymal transition and invasiveness by Bocca, Claudia, Ievolella, Monica, Autelli, Riccardo, Motta, Manuela, Mosso, Luciano, Torchio, Bruno, Bozzo, Francesca, Cannito, Stefania, Paternostro, Claudia, Colombatto, Sebastiano, Parola, Maurizio, Miglietta, Antonella

“…Cyclooxygenase-2 (COX-2) is overexpressed in several malignancies and is implicated in breast cancer progression. We investigated whether changes in COX-2…”
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Autophagy of metallothioneins prevents TNF-induced oxidative stress and toxicity in hepatoma cells by Ullio, Chiara, Brunk, Ulf T, Urani, Chiara, Melchioretto, Pasquale, Bonelli, Gabriella, Baccino, Francesco M, Autelli, Riccardo

“…Lysosomal membrane permeabilization (LMP) induced by oxidative stress has recently emerged as a prominent mechanism behind TNF cytotoxicity. This pathway…”
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Microwave-Assisted, Solid-State Procedure to Covalently Conjugate Hyaluronic Acid to Curcumin: Validation of a Green Synthetic Protocol by Verdoliva, Valentina, Muzio, Giuliana, Autelli, Riccardo, Saviano, Michele, Bedini, Emiliano, De Luca, Stefania

“…A microwave-assisted esterification reaction to prepare hyaluronan–curcumin derivatives by employing a solvent-free process was developed. In particular, a…”
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Biomolecular, Histological, Clinical, and Radiological Analyses of Dental Implant Bone Sites Prepared Using Magnetic Mallet Technology: A Pilot Study in Animals by Schierano, Gianmario, Baldi, Domenico, Peirone, Bruno, Mauthe von Degerfeld, Mitzy, Navone, Roberto, Bragoni, Alberto, Colombo, Jacopo, Autelli, Riccardo, Muzio, Giuliana

“…Background. A new instrumentation exploiting magneto-dynamic technology (mallet) proposed for implant site preparation was investigated. Methods. In the tibias…”
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Sphingosine mediates TNFα-induced lysosomal membrane permeabilization and ensuing programmed cell death in hepatoma cells by Ullio, Chiara, Casas, Josefina, Brunk, Ulf T., Sala, Giuseppina, Fabriàs, Gemma, Ghidoni, Riccardo, Bonelli, Gabriella, Baccino, Francesco M., Autelli, Riccardo

“…Normally, cell proliferation and death are carefully balanced in higher eukaryotes, but one of the most important regulatory mechanisms, apoptosis, is upset in…”
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JNK and ERK1/2 pathways have a dual opposite effect on the expression of BACE1 by Tamagno, Elena, Guglielmotto, Michela, Giliberto, Luca, Vitali, Antonella, Borghi, Roberta, Autelli, Riccardo, Danni, Oliviero, Tabaton, Massimo

“…Abstract The activity of β-secretase (BACE1), the endo-protease essential for the production of amyloid β (Aβ) peptides, is increased in brain of late-onset…”
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4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells by ZAMARA, Elena, NOVO, Erica, AUTELLI, Riccardo, COLOMBATTO, Sebastiano, DIANZANI, Mario Umberto, PINZANI, Massimo, PAROLA, Maurizio, MARRA, Fabio, GENTILINI, Alessandra, ROMANELLI, Roberto Giulio, CALIGIURI, Alessandra, ROBINO, Gaia, TAMAGNO, Elena, ARAGNO, Manuela, DANNI, Oliviero

“…4-Hydroxynonenal (HNE) is a putative pro-fibrogenic product of oxidative stress able to elicit apoptosis and cytotoxicity in several cell types. This study has…”
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Alterations of Cell Volume Regulation in the Development of Hepatocyte Necrosis by Carini, Rita, Autelli, Riccardo, Bellomo, Giorgio, Albano, Emanuele

“…Intracellular Na+accumulation has been shown to contribute to hepatocyte death caused by anoxia or oxidative stress. In this study we have investigated the…”
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Autophagy Triggers Tamoxifen Resistance in Human Breast Cancer Cells by Preventing Drug-Induced Lysosomal Damage by Actis, Chiara, Muzio, Giuliana, Autelli, Riccardo

“…Endocrine resistance is a major complication during treatment of estrogen receptor-positive breast cancer. Although autophagy has recently gained increasing…”
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) by Klionsky, Daniel, Abdel-Aziz, Amal Kamal, Abdelfatah, Sara, Abdellatif, Mahmoud, Abdoli, Asghar, Abel, Steffen, Abeliovich, Hagai, Abildgaard, Marie, Abudu, Yakubu Princely, Acevedo-Arozena, Abraham, Adamopoulos, Iannis, Adeli, Khosrow, Adolph, Timon, Adornetto, Annagrazia, Aflaki, Elma, Agam, Galila, Agarwal, Anupam, Aggarwal, Bharat, Agnello, Maria, Agostinis, Patrizia, Agrewala, Javed, Agrotis, Alexander, Aguilar, Patricia, Ahmad, S. Tariq, Ahmed, Zubair, Ahumada-Castro, Ulises, Aits, Sonja, Aizawa, Shu, Akkoc, Yunus, Akoumianaki, Tonia, Akpinar, Hafize Aysin, Al-Abd, Ahmed, Al-Akra, Lina, Al-Gharaibeh, Abeer, Alaoui-Jamali, Moulay, Alberti, Simon, Alcocer-Gómez, Elísabet, Alessandri, Cristiano, Ali, Muhammad, Alim Al-Bari, M. Abdul, Aliwaini, Saeb, Alizadeh, Javad, Almacellas, Eugènia, Almasan, Alexandru, Alonso, Alicia, Alonso, Guillermo, Altan-Bonnet, Nihal, Altieri, Dario, Álvarez, Élida, Alves, Sara, Alves da Costa, Cristine, Alzaharna, Mazen, Amadio, Marialaura, Amantini, Consuelo, Amaral, Cristina, Ambrosio, Susanna, Amer, Amal, Ammanathan, Veena, An, Zhenyi, Andersen, Stig, Andrabi, Shaida, Andrade-Silva, Magaiver, Andres, Allen, Angelini, Sabrina, Ann, David, Anozie, Uche, Ansari, Mohammad, Antas, Pedro, Antebi, Adam, Antón, Zuriñe, Anwar, Tahira, Apetoh, Lionel, Apostolova, Nadezda, Araki, Toshiyuki, Araki, Yasuhiro, Arasaki, Kohei, Araújo, Wagner, Araya, Jun, Arden, Catherine, Arévalo, Maria-Angeles, Arguelles, Sandro, Arias, Esperanza, Arikkath, Jyothi, Arimoto, Hirokazu, Ariosa, Aileen, Armstrong-James, Darius, Arnauné-Pelloquin, Laetitia, Aroca, Angeles, Arroyo, Daniela, Arsov, Ivica, Artero, Rubén, Asaro, Dalia Maria Lucia, Aschner, Michael, Ashrafizadeh, Milad, Ashur-Fabian, Osnat, Atanasov, Atanas, Au, Alicia, Auberger, Patrick, Auner, Holger, Aurelian, Laure

“…In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many…”
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Agmatine inhibits the proliferation of rat hepatoma cells by modulation of polyamine metabolism by Gardini, Giulia, Cravanzola, Carlo, Autelli, Riccardo, Testore, Giovanni, Cesa, Roberta, Morando, Laura, Solinas, Sandro Paolo, Muzio, Giuliana, Grillo, Maria Angelica, Colombatto, Sebastiano

“…Background/Aims: Previous experiments have shown that agmatine, the product of arginine decarboxylase, is transported in competition with putrescine into…”
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Oncostatin M is overexpressed in NASH‐related hepatocellular carcinoma and promotes cancer cell invasiveness and angiogenesis by Di Maira, Giovanni, Foglia, Beatrice, Napione, Lucia, Turato, Cristian, Maggiora, Marina, Sutti, Salvatore, Novo, Erica, Alvaro, Maria, Autelli, Riccardo, Colombatto, Sebastiano, Bussolino, Federico, Carucci, Patrizia, Gaia, Silvia, Rosso, Chiara, Biasiolo, Alessandra, Pontisso, Patrizia, Bugianesi, Elisabetta, Albano, Emanuele, Marra, Fabio, Parola, Maurizio, Cannito, Stefania

“…Oncostatin M (OSM) is a pleiotropic cytokine of the interleukin (IL)‐6 family that contributes to the progression of chronic liver disease. Here we…”
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up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α by Guglielmotto, Michela, Aragno, Manuela, Autelli, Riccardo, Giliberto, Luca, Novo, Erica, Colombatto, Sebastiano, Danni, Oliviero, Parola, Maurizio, Smith, Mark A, Perry, George, Tamagno, Elena, Tabaton, Massimo

“…While it is well established that stroke and cerebral hypoperfusion are both significant risk factors for Alzheimer's disease, the molecular link between…”
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Apoptosis induced by clofibrate in Yoshida AH-130 hepatoma cells by Canuto, Rosa A., Muzio, Giuliana, Maggiora, Marina, Trombetta, Antonella, Martinasso, Germana, Autelli, Riccardo, Costelli, Paola, Bonelli, Gabriella, Baccino, Francesco M.

“…Clofibrate is a hypolipidemic drug belonging to the peroxisome proliferator (42) family. PPs are well-recognized hepatocarcinogens, though only for rodents and…”
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Oxidative stress activates a positive feedback between the γ- and β-secretase cleavages of the β-amyloid precursor protein by Tamagno, Elena, Guglielmotto, Michela, Aragno, Manuela, Borghi, Roberta, Autelli, Riccardo, Giliberto, Luca, Muraca, Giuseppe, Danni, Oliviero, Zhu, Xiongwei, Smith, Mark A, Perry, George, Jo, Dong-Gyu, Mattson, Mark P, Tabaton, Massimo

“…Sequential cleavages of the β-amyloid precursor protein cleaving enzyme 1 (BACE1) by β-secretase and γ-secretase generate the amyloid β-peptides, believed to…”
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Oncostatin M is overexpressed in NASH-related hepatocellular carcinoma and promotes cancer cell invasiveness and angiogenesis by Maira, G., Foglia, B., Napione, L., Turato, C., Maggiora, M., Sutti, S., Alvaro, Maria, Autelli, Riccardo, Colombatto, Sebastiano, Bussolino, Federico, Carucci, Patrizia, Gaia, Silvia, Rosso, Chiara, Biasiolo, Alessandra, Pontisso, Patrizia, Bugianesi, Elisabetta, Albano, Emanuele, Marra, Fabio, Parola, Maurizio, Cannito, Stefania

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Hypoxia up-regulates SERPINB3 through HIF-2α in human liver cancer cells by Cannito, Stefania, Turato, Cristian, Paternostro, Claudia, Biasiolo, Alessandra, Colombatto, Sebastiano, Cambieri, Irene, Quarta, Santina, Novo, Erica, Morello, Elisabetta, Villano, Gianmarco, Fasolato, Silvano, Musso, Tiziana, David, Ezio, Tusa, Ignazia, Rovida, Elisabetta, Autelli, Riccardo, Smedile, Antonina, Cillo, Umberto, Pontisso, Patrizia, Parola, Maurizio

“…SERPINB3 is a cysteine-proteases inhibitor up-regulated in a significant number of cirrhotic patients carrying hepatocellular carcinoma (HCC) and recently…”
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