Search Results - "Austin, C. A."

Alkali Metal Cation Interactions with 15-Crown‑5 in the Gas Phase: Revisited by Armentrout, P. B, Austin, C. A, Rodgers, M. T

“…Quantitative interactions of the alkali metal cations with the cyclic 15-crown-5 polyether ligand (15C5) are studied. In this work, Rb+(15C5) and Cs+(15C5)…”
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Alkali Metal Cation–Hexacyclen Complexes: Effects of Alkali Metal Cation Size on the Structure and Binding Energy by Austin, C. A, Rodgers, M. T

“…Threshold collision-induced dissociation (CID) of alkali metal cation–hexacyclen (ha18C6) complexes, M+(ha18C6), with xenon is studied using guided ion beam…”
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A framework for automated gene selection in genomic applications by Lazo de la Vega, L., Yu, W., Machini, K., Austin-Tse, C.A., Hao, L., Blout Zawatsky, C.L., Mason-Suares, H., Green, R.C., Rehm, H.L., Lebo, M.S.

“…An efficient framework to identify disease-associated genes is needed to evaluate genomic data for both individuals with an unknown disease etiology and those…”
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Fear of falling, falls efficacy, and health outcomes in older people following hip fracture by Mckee, K. J., Orbell, S., Austin, C. A., Bettridge, R., Liddle, B. J., Morgan, K., Radley, Kate

“…Purpose : This study sought to determine whether fear of falling and falls efficacy independently contribute to the prediction of health outcomes after a fall,…”
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Site-specific DNA cleavage by mammalian DNA topoisomerase II induced by novel flavone and catechin derivatives by AUSTIN, C. A, PATEL, S, ONO, K, NAKANE, H, FISHER, L. M

“…Four naturally occurring flavones (baicalein, quercetin, quercetagetin and myricetin) and two novel catechins [(-)-epicatechin gallate and (-)-epigallocatechin…”
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Quantitation of DNA topoisomerase IIα and β in human leukaemia cells by immunoblotting by PADGET, K, PEARSON, A. D. J, AUSTIN, C. A

“…DNA topoisomerase II (topo II) is an essential nuclear enzyme and is the target for etoposide, which is used in the therapy of childhood acute lymphoblastic…”
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A new regimen for starting warfarin therapy in out‐patients by Oates, A., Jackson, P. R., Austin, C. A., Channer, K. S.

“…Aims  Oral anticoagulation is increasingly used in elderly patients with atrial fibrillation to prevent embolic phenomena. The use of anticoagulants in this…”
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Screening for visual impairment in elderly patients with hip fracture: validating a simple bedside test by SQUIRRELL, D. M, KENNY, J, MAWER, N, GUPTA, M, WEST, J, CURRIE, Z. I, PEPPER, I. M, AUSTIN, C. A

“…1. To assess the prevalence of visual impairment in those patients who sustain proximal hip fracture after a simple fall. 2. To test the validity of a simple…”
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Schedule-dependent response of neuroblastoma cell lines to combinations of etoposide and cisplatin by MECZES, E. L, PEARSON, A. D. J, AUSTIN, C. A, TILBY, M. J

“…The growth inhibitory effects of cisplatin and etoposide on neuroblastoma cell lines were investigated in several scheduled combinations. Results were analyzed…”
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Poly(ADP-ribose) Metabolism Is Essential for Proper Nucleoprotein Exchange During Mouse Spermiogenesis by Meyer-Ficca, Mirella L, Ihara, Motomasa, Lonchar, Julia D, Meistrich, Marvin L, Austin, Caroline A, Min, Wookee, Wang, Zhao-Qi, Meyer, Ralph G

“…Sperm chromatin is organized in a protamine-based, highly condensed form, which protects the paternal chromosome complement in transit, facilitates…”
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An investigation into the formation of N- [2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 6-[2-(dimethylamino)ethylamino]- 3-hydroxy-7H-indeno[2,1-C]quinolin-7-one dihydrochloride (TAS-103) stabilised DNA topoisomerase I and II cleavable complexes in human leukaemia cells by Padget, Kay, Stewart, Alistair, Charlton, Peter, Tilby, Michael J, Austin, Caroline A

“…The antitumour agents DACA (XR5000; N-[2-(dimethylamino)ethyl]acridine-4-carboxamide) and TAS-103 (6-[2-(dimethylamino)ethylamino]-3-hydroxy-7 H-indeno[2,1-…”
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Complementation of temperature-sensitive topoisomerase II mutations in Saccharomyces cerevisiae by a human TOP2β construct allows the study of topoisomerase IIβ inhibitors in yeast by MECZES, E. L, MARSH, K. L, FISHER, L. M, PERENNA ROGERS, M, AUSTIN, C. A

“…We show herein that human DNA topoisomerase II beta is functional in yeast. It can complement a yeast temperature-sensitive mutation in topoisomerase II. The…”
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Eukaryotic DNA topoisomerase IIβ by Austin, Caroline A., Marsh, Katherine L.

“…Type II DNA topoisomerase activity is required to change DNA topology. It is important in the relaxation of DNA supercoils generated by cellular processes,…”
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Amsacrine-promoted DNA cleavage site determinants for the two human DNA topoisomerase II isoforms α and β by Marsh, Katherine L., Willmore, Elaine, Tinelli, Stella, Cornarotti, Mariagrazia, Meczes, Emma L., Capranico, Giovanni, Fisher, L.Mark, Austin, Caroline A.

“…Site-specific DNA cleavage by topoisomerase II (EC 5.99.1.3) is induced by many antitumour drugs. Although human cells express two genetically distinct…”
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Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development by Capranico, G, Tinelli, S, Austin, C A, Fisher, M L, Zunino, F

“…The expression of DNA topoisomerase II alpha and beta genes was studied in murine normal tissues. Northern blot analysis using probes specific for the two…”
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Visual factors should be assessed in older people presenting with falls or hip fracture by Abdelhafiz, Ahmed H., Austin, Christopher A.

“…Visual impairment, although not routinely assessed, is an important risk factor for falls and hip fracture in older people. Impaired vision is highly prevalent…”
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Novel HeLa topoisomerase II is the II beta isoform: complete coding sequence and homology with other type II topoisomerases by Austin, C A, Sng, J H, Patel, S, Fisher, L M

“…DNA topoisomerase (topo) II mediates DNA strand passage in an ATP-dependent reaction. Human cell lines express at least two genetically distinct forms of the…”
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sox30: a novel zebrafish sox gene expressed in a restricted manner at the midbrain-hindbrain boundary during neurogenesis by De Martino, S P, Errington, F, Ashworth, A, Jowett, T, Austin, C A

“…The Sox family of proteins is thought to act to regulate gene expression in a wide variety of developmental processes. Here we describe the cloning of sox30, a…”
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Isolation and characterization of a human cDNA clone encoding a novel DNA topoisomerase II homologue from HeLa cells by Austin, Caroline A., Fisher, L.Mark

“…We have isolated and sequenced 3 human DNA topoisomerase II (topo II) partial cDNA clones from a HeLa carcinoma cell cDNA library. Two clones were identical to…”
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Deacetylase Activity Associates with Topoisomerase II and Is Necessary for Etoposide-induced Apoptosis by Johnson, Colin A., Padget, Kay, Austin, Caroline A., Turner, Bryan M.

“…DNA topoisomerase II (topo II) is a ubiquitous nuclear enzyme that is involved in DNA replication, transcription, chromosome segregation, and apoptosis. Here…”
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