Search Results - "Aust, G."

From single cells to tissue architecture—a bottom-up approach to modelling the spatio-temporal organisation of complex multi-cellular systems by Galle, J., Hoffmann, M., Aust, G.

“…Collective phenomena in multi-cellular assemblies can be approached on different levels of complexity. Here, we discuss a number of mathematical models which…”
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Different in vivo and in vitro transformation of intestinal stem cells in mismatch repair deficiency by Keysselt, K, Kreutzmann, T, Rother, K, Kerner, C, Krohn, K, Przybilla, J, Buske, P, Löffler-Wirth, H, Loeffler, M, Galle, J, Aust, G

“…Mutations in mismatch repair (MMR) genes result in microsatellite instability (MSI) and early onset of colorectal cancer. To get mechanistic insights into the…”
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Percutaneous absorption and distribution of organophosphates (chlorpyrifos and dichlorvos) following dermal exposure and decontamination scenarios using in vitro human skin model by Moore, C.A., Wilkinson, S.C., Blain, P.G., Dunn, M., Aust, G.A., Williams, F.M.

“…•Looked at low level dermal exposure to organophosphates from civilian perspective.•Studied absorption of chlorpyrifos and dichlorvos from 3 vehicles (IPA, IPM…”
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Ca(2+)-binding protein expression in primary human thyrocytes by Lorenz, S, Aust, G, Krohn, K

“…We recently identified several Ca(2+)-binding proteins (CaBP) from the S100 and annexin family to be regulated by TSH in FRTL-5 cells. Here, we study the…”
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Good Clinical Outcome After Accidental Intra-arterial Injection of Flunitrazepam Tablets in 16 Drug Abusers with Critical Limb Ischaemia by Rohm, S, Staab, H, Schulz, H, Richter, O, Aust, G

“…Objectives Inadvertent intra-arterial injection of flunitrazepam tablets intended for intravenous use by drug abusers has devastating effects. We report here…”
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Good Clinical Outcome After Accidental Intra-arterial Injection of Flunitrazepam Tablets in 16 Drug Abusers with Critical Limb Ischaemia by Rohm, S, Staab, H, Schulz, H, Richter, O, Aust, G

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Use of a human skin in vitro model to investigate the influence of ‘every-day’ clothing and skin surface decontamination on the percutaneous penetration of organophosphates by Moore, C.A., Wilkinson, S.C., Blain, P.G., Dunn, M., Aust, G.A., Williams, F.M.

“…•Investigated role of ‘everyday’ clothing at reducing dermal exposure to chemicals.•Studied low level exposure to dichlorvos and chlorpyrifos from different…”
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Individual cell‐based models of the spatial‐temporal organization of multicellular systems—Achievements and limitations by Galle, J., Aust, G., Schaller, G., Beyer, T., Drasdo, D.

“…Computational approaches of multicellular assemblies have reached a stage where they may contribute to unveil the processes that underlie the organization of…”
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Comprehensive analysis of transcript start sites in ly49 genes reveals an unexpected relationship with gene function and a lack of upstream promoters by Gays, Frances, Koh, Alan S C, Mickiewicz, Katarzyna M, Aust, Jonathan G, Brooks, Colin G

“…Comprehensive analysis of the transcription start sites of the Ly49 genes of C57BL/6 mice using the oligo-capping 5'-RACE technique revealed that the genes…”
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The role of CXCR5 and its ligand CXCL13 in the compartmentalization of lymphocytes in thyroids affected by autoimmune thyroid diseases by Aust, G, Sittig, D, Becherer, L, Anderegg, U, Schutz, A, Lamesch, P, Schmucking, E

“…OBJECTIVE: Graves' disease (GD) and Hashimoto's thyroiditis (HT) are characterized by lymphocytic infiltrates partly resembling secondary lymphoid follicles in…”
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Reduced expression of stromal-derived factor 1 in autonomous thyroid adenomas and its regulation in thyroid-derived cells by AUST, G, STEINERT, M, KIESSLING, S, KAMPRAD, M, SIMCHEN, C

“…Stromal-derived factor 1 (SDF-1) and CXCR4 comprise a unique chemokine/chemokine receptor pair, exhibiting important functions in morphogenesis and growth…”
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Graves’ disease and Hashimoto’s thyroiditis in monozygotic twins: case study as well as transcriptomic and immunohistological analysis of thyroid tissues by Aust, G, Krohn, K, Morgenthaler, N G, Schröder, S, Schütz, A, Edelmann, J, Brylla, E

“…Objective: To report on the rare simultaneous occurrence of Graves’ disease (GD) and Hashimoto’s thyroiditis (HT) in monozygotic twins. Design: We compared the…”
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Expression of ADAM15 in lung carcinomas by SCHIITZ, A, HÄRTIG, W, WOBUS, M, GROSCHE, J, WITTEKIND, Ch, AUST, G

“…ADAM15, a member of the ADAM (a disintegrin and metalloprotease) family, is a membrane protein containing both protease and adhesion domains and may, thus, be…”
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Differential expression and activity status of MMP-1, MMP-2 and MMP-9 in tumor and stromal cells of squamous cell carcinomas of the lung by Schütz, A, Schneidenbach, D, Aust, G, Tannapfel, A, Steinert, M, Wittekind, C

“…Matrix metalloproteinases (MMPs) play a key role in cancer progression. Interstitial collagenase (MMP-1) and type IV collagenases (MMP-2, MMP-9) are involved…”
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Multiple Cytokines Regulate the NK Gene Complex-Encoded Receptor Repertoire of Mature NK Cells and T Cells by Gays, Frances, Martin, Kimberley, Kenefeck, Rupert, Aust, Jonathan G, Brooks, Colin G

“…Mature NK cells comprise a highly diverse population of lymphocytes that express different permutations of receptors to facilitate recognition of diseased…”
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influence of soil properties on the development of grape phylloxera populations in Austrian viticulture by Reisenzein, H, Pfeffer, M, Aust, G, Baumgarten, A

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Ischemic preconditioning in a rat adipocutaneous flap model by Dacho, A, Lyutenski, S, Aust, G, Dietz, A

“…Flap necrosis in ear, nose, and throat surgery, especially in high-risk groups, is not rare, but not all of the individual pathophysiological processes are…”
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Bovine eotaxin (CCL11)—an unusual member of the eotaxin group—attracts eosinophils in vitro but is not responsible for eosinophilia in the ovary by Vogel, B., Klinder, A., Sittig, D., Aust, G.

“…Under physiological conditions normally characterised by low tissue infiltration of eosinophils, a conspicuous number of these cells are attracted into the…”
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Correlation between expression of selectins and migration of eosinophils into the bovine ovary during the periovulatory period by Rohm, F, Spanel-Borowski, K, Eichler, W, Aust, G

“…Leukocytes enter specific ovarian areas at a precisely defined moment, influencing cyclically changing structures such as follicles and corpora lutea. As yet,…”
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GRO-alpha in normal and pathological thyroid tissues and its regulation in thyroid-derived cells by Aust, G, Steinert, M, Boltze, C, Kiessling, S, Simchen, C

“…Thyroid glands affected by Graves' disease (GD) show striking leukocytic infiltration, mainly by T-cells. The mechanisms by which the various leukocytes are…”
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