Search Results - "Ausems, M G E M"

Breast cancer risk after salpingo-oophorectomy in healthy BRCA1/2 mutation carriers: revisiting the evidence for risk reduction by Heemskerk-Gerritsen, B A M, Seynaeve, C, van Asperen, C J, Ausems, M G E M, Collée, J M, van Doorn, H C, Gomez Garcia, E B, Kets, C M, van Leeuwen, F E, Meijers-Heijboer, H E J, Mourits, M J E, van Os, T A M, Vasen, H F A, Verhoef, S, Rookus, M A, Hooning, M J

“…Previous studies have reported a breast cancer (BC) risk reduction of approximately 50% after risk-reducing salpingo-oophorectomy (RRSO) in BRCA1/2 mutation…”
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TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes by Ruijs, Marielle W G, Verhoef, Senno, Rookus, Matti A, Pruntel, Roelof, van der Hout, Annemarie H, Hogervorst, Frans B L, Kluijt, I, Sijmons, Rolf H, Aalfs, Cora M, Wagner, Anja, Ausems, Margreet G E M, Hoogerbrugge, Nicoline, van Asperen, Christi J, Gomez Garcia, Encarna B, Meijers-Heijboer, Hanne, Ten Kate, Leo P, Menko, Fred H, van 't Veer, Laura J

“…BACKGROUND Li-Fraumeni syndrome (LFS) is a rare autosomal dominant cancer predisposition syndrome. Most families fulfilling the classical diagnostic criteria…”
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Development of a plain-language guide for discussing breast cancer genetic counseling and testing with patients with limited health literacy by van der Giessen, J. A. M, Ausems, M. G. E. M., van Riel, E., de Jong, A., Fransen, M. P., van Dulmen, S.

“…Purpose Due to limited health literacy and resulting ineffective communication between healthcare professionals and patients, not all eligible patients are…”
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BRCA1 mutation carriers have a lower number of mature oocytes after ovarian stimulation for IVF/PGD by Derks-Smeets, I. A. P., van Tilborg, T. C., van Montfoort, A., Smits, L., Torrance, H. L., Meijer-Hoogeveen, M., Broekmans, F., Dreesen, J. C. F. M., Paulussen, A. D. C., Tjan-Heijnen, V. C. G., Homminga, I., van den Berg, M. M. J., Ausems, M. G. E. M., de Rycke, M., de Die-Smulders, C. E. M., Verpoest, W., van Golde, R.

“…Purpose The aim of this study was to determine whether BRCA1/2 mutation carriers produce fewer mature oocytes after ovarian stimulation for in vitro…”
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Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations: retrospective cohort study (GENE-RAD-RISK) by Pijpe, Anouk, Andrieu, Nadine, Easton, Douglas F, Kesminiene, Ausrele, Cardis, Elisabeth, Noguès, Catherine, Gauthier-Villars, Marion, Lasset, Christine, Fricker, Jean-Pierre, Peock, Susan, Frost, Debra, Evans, D Gareth, Eeles, Rosalind A, Paterson, Joan, Manders, Peggy, van Asperen, Christi J, Ausems, Margreet G E M, Meijers-Heijboer, Hanne, Thierry-Chef, Isabelle, Hauptmann, Michael, Goldgar, David, Rookus, Matti A, van Leeuwen, Flora E

“…Objective To estimate the risk of breast cancer associated with diagnostic radiation in carriers of BRCA1/2 mutations.Design Retrospective cohort study…”
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Repeated nipple fluid aspiration: compliance and feasibility results from a prospective multicenter study by de Groot, J S, Moelans, C B, Elias, S G, Hennink, A, Verolme, B, Suijkerbuijk, K P M, Jager, A, Seynaeve, C, Bos, P, Witkamp, A J, Ausems, M G E M, van Diest, P J, van der Wall, E

“…Despite intensive surveillance, a high rate of interval malignancies is still seen in women at increased breast cancer risk. Therefore, novel screening…”
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Referral to cancer genetic counseling: do migrant status and patients’ educational background matter? by van der Giessen, J. A. M., van Riel, E., Velthuizen, M. E., van Dulmen, A. M., Ausems, M. G. E. M.

“…Participation rates in cancer genetic counseling differ among populations, as patients with a lower educational background and migrant patients seem to have…”
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Mainstream germline genetic testing in men with metastatic prostate cancer: design and protocol for a multicenter observational study by Vlaming, Michiel, Bleiker, Eveline M A, van Oort, Inge M, Kiemeney, Lambertus A L M, Ausems, Margreet G E M

“…In international guidelines, germline genetic testing is recommended for patients with metastatic prostate cancer. Before undergoing germline genetic testing,…”
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Information Provision Regarding Health-Related Direct-to-Consumer Genetic Testing for Dutch Consumers: An in-Depth Content Analysis of Sellers' Websites by Bruins, Danny, Onstwedder, Suzanne M, Cornel, Martina C, Ausems, Margreet G E M, van Mil, Marc H W, Rigter, Tessel

“…: Previous studies have suggested that information offered by sellers of health-related direct-to-consumer genetic tests (DTC-GTs) is often incomplete,…”
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Patient-centered research: how do women tolerate nipple fluid aspiration as a potential screening tool for breast cancer? by Patuleia, Susana I. S, Moelans, Cathy B, Koopman, Jasmijn, van Steenhoven, Julia E. C, van Dalen, Thijs, van der Pol, Carmen C, Jager, Agnes, Ausems, Margreet G. E. M, van Diest, Paul J, van der Wall, Elsken, Suijkerbuijk, Karijn P. M

“…Abstract Background Nipple fluid aspiration (NFA) is a technique to acquire nipple aspirate fluid (NAF), which is considered a rich source of breast-specific…”
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Surgical Oncologists and Nurses in Breast Cancer Care are Ready to Provide Pre-Test Genetic Counseling by Bokkers, K., Bleiker, E. M. A., Aalfs, C. M., van Dalen, T., Velthuizen, M. E., Duijveman, P., Sijmons, R. H., Koole, W., Schoenmaeckers, E. J. P., Ausems, M. G. E. M.

“…Background Pre-test genetic counseling for patients with breast cancer is increasingly being provided by nongenetic healthcare professionals. We evaluated the…”
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Mainstream genetic testing for women with ovarian cancer provides a solid basis for patients to make a well-informed decision about genetic testing by Bokkers, Kyra, Bleiker, Eveline M. A, Hoogendam, Jacob P, Velthuizen, Mary E, Schreuder, Henk W. R, Gerestein, Cornelis G, Lange, Joost G, Louwers, Jacqueline A, Koudijs, Marco J, Ausems, Margreet G. E. M, Zweemer, Ronald P

“…Abstract Background There is a growing need for genetic testing of women with epithelial ovarian cancer. Mainstream genetic testing provides an alternative…”
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Survival after bilateral risk-reducing mastectomy in healthy BRCA1 and BRCA2 mutation carriers by Heemskerk-Gerritsen, Bernadette A. M., Jager, Agnes, Koppert, Linetta B., Obdeijn, A. Inge-Marie, Collée, Margriet, Meijers-Heijboer, Hanne E. J., Jenner, Denise J., Oldenburg, Hester S. A., van Engelen, Klaartje, de Vries, Jakob, van Asperen, Christi J., Devilee, Peter, Blok, Marinus J., Kets, C. Marleen, Ausems, Margreet G. E. M., Seynaeve, Caroline, Rookus, Matti A., Hooning, Maartje J.

“…Background In healthy BRCA1/2 mutation carriers, bilateral risk-reducing mastectomy (BRRM) strongly reduces the risk of developing breast cancer (BC); however,…”
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HIF-1α overexpression in ductal carcinoma in situ of the breast in BRCA1 and BRCA2 mutation carriers by van der Groep, Petra, van Diest, Paul J, Smolders, Yvonne H C M, Ausems, Margreet G E M, van der Luijt, Rob B, Menko, Fred H, Bart, Joost, de Vries, Elisabeth G E, van der Wall, Elsken

“…Recent studies have revealed that BRCA1 and BRCA2 germline mutation-related breast cancers show frequent overexpression of hypoxia inducible factor-1α…”
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Recontacting non-BRCA1/2 breast cancer patients for germline CHEK2 c.1100del pathogenic variant testing: uptake and patient experiences by Velthuizen, Mary E, van der Luijt, Rob B, de Vries, Beja J, Koudijs, Marco J, Bleiker, Eveline M A, Ausems, Margreet G E M

“…CHEK2 has been recognized as a breast cancer risk gene with moderate effect. Women who have previously tested negative for a BRCA1/2 gene germline pathogenic…”
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Microsatellite Instability, Immunohistochemistry, and Additional PMS2 Staining in Suspected Hereditary Nonpolyposis Colorectal Cancer by DE JONG, Andrea E, VAN PUIJENBROEK, Marjo, VASEN, Hans F. A, MORREAU, Hans, HENDRIKS, Yvonne, TOPS, Carli, WIJNEN, Juul, AUSEMS, Margreet G. E. M, MEIJERS-HEIJBOER, Hanne, WAGNER, Anja, VAN OS, Theo A. M, BRÖCKER-VRIENDS, Annette H. J. T

“…Purpose: Immunohistochemistry (IHC) and microsatellite instability (MSI) analysis can be used to identify patients with a possible DNA mismatch repair defect…”
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ASO Author Reflections: The Role of Surgeons and Nurse Specialists in the Mainstreaming of Genetic Testing for Breast Cancer Patients by Bokkers, Kyra, Ausems, Margreet G. E. M.

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Body weight and risk of breast cancer in BRCA1/2 mutation carriers by Manders, Peggy, Pijpe, Anouk, Hooning, Maartje J, Kluijt, Irma, Vasen, Hans F. A, Hoogerbrugge, Nicoline, van Asperen, Christi J, Meijers-Heijboer, Hanne, Ausems, Margreet G. E. M, van Os, Theo A, Gomez-Garcia, Encarna B, Brohet, Richard M, van Leeuwen, Flora E, Rookus, Matti A

“…Obesity is an established risk factor for postmenopausal breast cancer in the general population. However, it is still unclear whether this association also…”
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Physical activity and the risk of breast cancer in BRCA1/2 mutation carriers by Pijpe, Anouk, Manders, Peggy, Brohet, Richard M., Collée, J. Margriet, Verhoef, Senno, Vasen, Hans F. A., Hoogerbrugge, Nicoline, van Asperen, Christi J., Dommering, Charlotte, Ausems, Margreet G. E. M., Aalfs, Cora M., Gomez-Garcia, Encarna B., van‘t Veer, Laura J., van Leeuwen, Flora E., Rookus, Matti A.

“…BRCA1/2 mutation carriers have a high lifetime risk of developing breast cancer. Differences in penetrance indicate that this risk may be influenced by…”
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Communication in cancer genetic counselling: does it reflect counselees' previsit needs and preferences? by PIETERSE, Ah, VAN DULMEN, Am, AUSEMS, Mgem, BEEMER, Fa, BENSI, Jm

“…This study sought to describe counsellor-counselee interaction during initial cancer genetic counselling consultations and to examine whether the communication…”
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