Search Results - "Ausín, Cristina"
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Use of glucocorticoids megadoses in SARS-CoV-2 infection in a spanish registry: SEMI-COVID-19
Published in PloS one (21-01-2022)“…To describe the impact of different doses of corticosteroids on the evolution of patients with COVID-19 pneumonia, based on the potential benefit of the…”
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2
Protection of the 2′-Hydroxy Function of Ribonucleosides as an Iminooxymethyl Propanoate and Its 2′-O-Deprotection through an Intramolecular Decarboxylative Elimination Process
Published in European journal of organic chemistry (01-12-2016)“…The design and implementation of 2′‐hydroxy protecting groups for ribonucleosides is still a daunting challenge to overcome when assembling RNA (ribonucleic…”
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3
The 2-Cyano-2,2-dimethylethanimine-N-oxymethyl Group for the 2′-Hydroxyl Protection of Ribonucleosides in the Solid-Phase Synthesis of RNA Sequences
Published in Chemistry : a European journal (02-04-2013)“…The reaction of 2‐cyano‐2‐methyl propanal with 2′‐O‐aminooxymethylribonucleosides leads to stable and yet reversible…”
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4
Assessment of heat-sensitive thiophosphate protecting groups in the development of thermolytic DNA oligonucleotide prodrugs
Published in Tetrahedron (01-01-2010)“…Heat-sensitive thiophosphate protecting groups derived from the alcohol 4 or 10 have provided insights in the design of DNA oligonucleotide prodrugs. Indeed,…”
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5
Permanent or reversible conjugation of 2′-O- or 5′-O-aminooxymethylated nucleosides with functional groups as a convenient and efficient approach to the modification of RNA and DNA sequences
Published in Nucleic acids research (01-03-2012)“…2′-O-Aminooxymethyl ribonucleosides are prepared from their 3′,5′-disilylated 2′-O-phthalimidooxymethyl derivatives by treatment with NH4F in MeOH. The…”
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6
Use of thermolytic protective groups to prevent G-tetrad formation in CpG ODN type D: structural studies and immunomodulatory activity in primates
Published in Nucleic acids research (01-12-2006)“…CpG oligodeoxynucleotides (ODN) show promise as immunoprotective agents and vaccine adjuvants. CpG ODN type D were shown to improve clinical outcome in rhesus…”
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7
Thermolytic CpG-containing DNA oligonucleotides as potential immunotherapeutic prodrugs
Published in Nucleic acids research (01-01-2005)“…A CpG-containing DNA oligonucleotide functionalized with the 2-(N-formyl-N-methyl)aminoethyl thiophosphate protecting group (CpG ODN fma1555) was prepared from…”
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8
Cyclic Phosphate-Linked Oligosaccharides: Synthesis and Conformational Behavior of Novel Cyclic Oligosaccharide Analogues
Published in Journal of organic chemistry (28-04-2006)“…CyPLOS (cyclic phosphate-linked oligosaccharides), that is, novel cyclic oligosaccharide surrogates, consisting of two, three, and four…”
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9
Safety outcomes when switching between biosimilars and reference biologics: A systematic review and meta-analysis
Published in PloS one (03-10-2023)“…Biosimilars are increasingly available for the treatment of many serious disorders, however some concerns persist about switching a patient to a biosimilar…”
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10
Synthesis of Amino- and Guanidino-G-Clamp PNA Monomers
Published in Organic letters (14-11-2002)“…Syntheses of the protected amino- and guanidino-G-clamp PNA monomers, 9a and 9b, respectively, have been accomplished in eight steps from 5-bromouracil…”
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11
Visceral extra‐abdominal panniculitis after COVID19
Published in International journal of rheumatic diseases (01-04-2023)“…“Retractile mesenteritis” was the first name given to a rare, benign, inflammatory disease that affects the adipose tissue of the intestinal mesentery and less…”
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12
Influence of smoking history on the evolution of hospitalized in COVID-19 positive patients: results from the SEMI-COVID-19 registry
Published in Medicina clinica (09-09-2022)“…Smoking can play a key role in SARS-CoV-2 infection and in the course of the disease. Previous studies have conflicting or inconclusive results on the…”
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13
31P NMR Study of the Desulfurization of Oligonucleoside Phosphorothioates Effected by “Aged” Trichloroacetic Acid Solutions
Published in Journal of organic chemistry (15-04-2005)“…When employing phosphoramidites 1a−d in the solid-phase synthesis of oligonucleoside phosphorothioates, the thermolytic 2-[N-methyl-N-(2-pyridyl)]aminoethyl…”
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14
Post-COVID-19 condition in pregnant and postpartum women: a long-term follow-up, observational prospective study
Published in EClinicalMedicine (01-01-2024)“…Post-COVID-19 condition has recently been defined as new or persistent common COVID-19 symptoms occurring three months after disease onset. The pathology of…”
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15
Real-Life Impact of Glucocorticoid Treatment in COVID-19 Mortality: A Multicenter Retrospective Study
Published in Journal of clinical medicine (13-10-2021)“…We aimed to determine the impact of steroid use in COVID-19 in-hospital mortality, in a retrospective cohort study of the SEMICOVID19 database of admitted…”
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16
Upper trunk brachial plexopathy as a consequence of prone positioning due to SARS‐CoV‐2 acute respiratory distress syndrome
Published in Muscle & nerve (01-11-2020)Get full text
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17
Solid-Phase Synthesis of Thermolytic DNA Oligonucleotides Functionalized with a Single 4-Hydroxy-1-butyl or 4-Phosphato-/Thiophosphato-1-butyl Thiophosphate Protecting Group
Published in Journal of organic chemistry (02-02-2007)“…Several thermolytic CpG-containing DNA oligonucleotides analogous to 1 have been synthesized to serve as potential immunotherapeutic oligonucleotide prodrug…”
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Long-term consequences of SARS-COV2 infection: Long-Covid patterns and possible public health implications
Published in Medicina clinica (08-10-2021)Get more information
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Post-COVID-19 condition in pregnant and postpartum women: a long-term follow-up, observational prospective studyResearch in context
Published in EClinicalMedicine (01-01-2024)“…Background: Post-COVID-19 condition has recently been defined as new or persistent common COVID-19 symptoms occurring three months after disease onset. The…”
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20
Use of glucocorticoids megadoses in SARS-CoV-2 infection in a spanish registry: SEMI-COVID-19
Published in PloS one (01-01-2022)“…ObjectiveTo describe the impact of different doses of corticosteroids on the evolution of patients with COVID-19 pneumonia, based on the potential benefit of…”
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