Search Results - "Auriche, C"
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Gene Therapy Progress and Prospects: Episomally maintained self-replicating systems
Published in Gene therapy (01-12-2004)“…The use of nonviral gene therapy vectors has been hampered by low level of transfection efficiency and lack of sustained gene expression. Episomal…”
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CFTR expression and activity from the human CFTR locus in BAC vectors, with regulatory regions, isolated by a single-step procedure
Published in Gene therapy (01-11-2010)“…We have assembled two BAC vectors containing a single fragment spanning the entire CFTR locus and including the upstream and downstream regions. The two…”
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INFLUENCE OF PSEUDOMONAS AERUGINOSA ON THE GROWTH RATE AND INTERNALIZATION OF BURKHOLDERIA CENOCEPACIA
Published in Journal of cystic fibrosis (01-07-2008)Get full text
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Molecular and cytological analysis of a 5.5 Mb minichromosome
Published in EMBO reports (01-02-2001)“…Mammalian artificial chromosomes (MACs) provide a new tool for the improvement of our knowledge of chromosome structure and function. Moreover, they constitute…”
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Use of a Human Minichromosome as a Cloning and Expression Vector for Mammalian Cells
Published in Human molecular genetics (01-08-1999)“…A natural human minichromosome (MC1) derived from human chromosome 1 was shown to be linear and to haveasizeof 5.5 Mb.Human IL-2 cDNA and the neo gene were…”
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SELECTION AND ANALYSIS OF SILENCING RNA FOR EFFICIENT DOWNREGULATION OF ENaC CHANNEL IN LUNG EPITHELIAL CELLS
Published in Journal of cystic fibrosis (01-07-2008)Get full text
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The Mec1p and Tel1p checkpoint kinases allow humanized yeast to tolerate chronic telomere dysfunctions by suppressing telomere fusions
Published in DNA repair (01-02-2009)“…In this work we report that budding yeasts carrying human-type telomeric repeats at their chromosome termini show a chronic activation of the Rad53-dependent…”
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Identification and validation of biomarkers for autism spectrum disorders
Published in Nature reviews. Drug discovery (01-01-2016)Get full text
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Functional human CFTR produced by a stable minichromosome
Published in EMBO reports (01-09-2002)“…Artificial chromosomes have been claimed to be the ideal vector for gene therapy, but their use has been hampered by an inability to produce stable and well…”
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Effect of BN 50730, a Specific PAF Antagonist, on PAF-Induced Platelet Aggregation and Skin Responses in Healthy Human Volunteers
Published in Drug Investigation (01-08-1994)Get full text
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