Search Results - "Aurelly, Michèle"

Rational Drug Design of Topically Administered Caspase 1 Inhibitors for the Treatment of Inflammatory Acne by Fournier, Jean-François, Clary, Laurence, Chambon, Sandrine, Dumais, Laurence, Harris, Craig Steven, Millois, Corinne, Pierre, Romain, Talano, Sandrine, Thoreau, Étienne, Aubert, Jérome, Aurelly, Michèle, Bouix-Peter, Claire, Brethon, Anne, Chantalat, Laurent, Christin, Olivier, Comino, Catherine, El-Bazbouz, Ghizlane, Ghilini, Anne-Laurence, Isabet, Tatiana, Lardy, Claude, Luzy, Anne-Pascale, Mathieu, Céline, Mebrouk, Kenny, Orfila, Danielle, Pascau, Jonathan, Reverse, Kevin, Roche, Didier, Rodeschini, Vincent, Hennequin, Laurent François

“…The use of an interleukin β antibody is currently being investigated in the clinic for the treatment of acne, a dermatological disorder affecting 650M persons…”
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Impact of Minor Structural Modifications on Properties of a Series of mTOR Inhibitors by Ouvry, Gilles, Clary, Laurence, Tomas, Loïc, Aurelly, Michèle, Bonnary, Laetitia, Borde, Emilie, Bouix-Peter, Claire, Chantalat, Laurent, Defoin-Platel, Claire, Deret, Sophie, Forissier, Mathieu, Harris, Craig S, Isabet, Tatiana, Lamy, Laurent, Luzy, Anne-Pascale, Pascau, Jonathan, Soulet, Catherine, Taddei, Alessandro, Taquet, Nathalie, Thoreau, Etienne, Varvier, Emeric, Vial, Emmanuel, Hennequin, Laurent F

“…Minor structural modificationssometimes single atom changescan have a dramatic impact on the properties of compounds. This is illustrated here on structures…”
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Squaramides as novel class I and IIB histone deacetylase inhibitors for topical treatment of cutaneous t-cell lymphoma by Fournier, Jean-François, Bhurruth-Alcor, Yushma, Musicki, Branislav, Aubert, Jérome, Aurelly, Michèle, Bouix-Peter, Claire, Bouquet, Karinne, Chantalat, Laurent, Delorme, Marion, Drean, Bénédicte, Duvert, Gwenaelle, Fleury-Bregeot, Nicolas, Gauthier, Blanche, Grisendi, Karine, Harris, Craig S., Hennequin, Laurent F., Isabet, Tatiana, Joly, Florence, Lafitte, Guillaume, Millois, Corinne, Morgentin, Rémy, Pascau, Jonathan, Piwnica, David, Rival, Yves, Soulet, Catherine, Thoreau, Étienne, Tomas, Loïc

“…[Display omitted] •A novel squaramide-based scaffold for HDAC inhibition is proposed.•Inhibitors are optimized for topical route of administration.•Aqueous and…”
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