Search Results - "Aurade, Frederic"

Pax3 and Pax7 Play Essential Safeguard Functions against Environmental Stress-Induced Birth Defects by Zalc, Antoine, Rattenbach, Revital, Auradé, Frédéric, Cadot, Bruno, Relaix, Frédéric

“…Exposure to environmental teratogenic pollutant leads to severe birth defects. However, the biological events underlying these developmental abnormalities…”
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SOXF factors regulate murine satellite cell self-renewal and function through inhibition of β-catenin activity by Alonso-Martin, Sonia, Auradé, Frédéric, Mademtzoglou, Despoina, Rochat, Anne, Zammit, Peter S, Relaix, Frédéric

“…Muscle satellite cells are the primary source of stem cells for postnatal skeletal muscle growth and regeneration. Understanding genetic control of satellite…”
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Samp1 is a component of TAN lines and is required for nuclear movement by Borrego-Pinto, Joana, Jegou, Thibaud, Osorio, Daniel S, Auradé, Frederic, Gorjánácz, Mátyás, Koch, Birgit, Mattaj, Iain W, Gomes, Edgar R

“…The position of the nucleus is regulated in different developmental stages and cellular events. During polarization, the nucleus moves away from the future…”
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Neural Crest Cell Lineage Restricts Skeletal Muscle Progenitor Cell Differentiation through Neuregulin1-ErbB3 Signaling by Ho, Andrew Tri Van, Hayashi, Shinichiro, Bröhl, Dominique, Auradé, Frédéric, Rattenbach, Révital, Relaix, Frédéric

“…Coordinating the balance between progenitor self-renewal and myogenic differentiation is required for a regulated expansion of the developing muscles. Previous…”
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Pax3- and Pax7-mediated Dbx1 regulation orchestrates the patterning of intermediate spinal interneurons by Gard, Chris, Gonzalez Curto, Gloria, Frarma, Youcef El-Mokhtar, Chollet, Elodie, Duval, Nathalie, Auzié, Valentine, Auradé, Frédéric, Vigier, Lisa, Relaix, Frédéric, Pierani, Alessandra, Causeret, Frédéric, Ribes, Vanessa

“…Transcription factors are key orchestrators of the emergence of neuronal diversity within the developing spinal cord. As such, the two paralogous proteins Pax3…”
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Generation of BAC transgenic tadpoles enabling live imaging of motoneurons by using the urotensin II-related peptide (ust2b) gene as a driver by Bougerol, Marion, Auradé, Frédéric, Lambert, François M, Le Ray, Didier, Combes, Denis, Thoby-Brisson, Muriel, Relaix, Frédéric, Pollet, Nicolas, Tostivint, Hervé

“…Xenopus is an excellent tetrapod model for studying normal and pathological motoneuron ontogeny due to its developmental morpho-physiological advantages. In…”
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Gene Expression Profiling of Muscle Stem Cells Identifies Novel Regulators of Postnatal Myogenesis by Alonso-Martin, Sonia, Rochat, Anne, Mademtzoglou, Despoina, Morais, Jessica, de Reyniès, Aurélien, Auradé, Frédéric, Chang, Ted Hung-Tse, Zammit, Peter S, Relaix, Frédéric

“…Skeletal muscle growth and regeneration require a population of muscle stem cells, the satellite cells, located in close contact to the myofiber. These cells…”
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A p57 conditional mutant allele that allows tracking of p57‐expressing cells by Mademtzoglou, Despoina, Alonso‐Martin, Sonia, Chang, Ted Hung‐Tse, Bismuth, Keren, Drayton‐Libotte, Bernadette, Aurade, Frédéric, Relaix, Frédéric

“…p57Kip2 (p57) is a maternally expressed imprinted gene regulating growth arrest which belongs to the CIP/KIP family of cyclin‐dependent kinase inhibitors…”
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Aurora B is dispensable for megakaryocyte polyploidization, but contributes to the endomitotic process by Lordier, Larissa, Chang, Yunhua, Jalil, Abdelali, Aurade, Frédéric, Garçon, Loïc, Lécluse, Yann, Larbret, Frédéric, Kawashima, Toshiyuki, Kitamura, Toshio, Larghero, Jérôme, Debili, Najet, Vainchenker, William

“…Polyploidization of megakaryocytes (MKs), the platelet precursors, occurs by endomitosis, a mitotic process that fails at late stages of cytokinesis…”
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Proteasome inhibitor bortezomib impairs both myelofibrosis and osteosclerosis induced by high thrombopoietin levels in mice by Wagner-Ballon, Orianne, Pisani, Didier F., Gastinne, Thomas, Tulliez, Micheline, Chaligné, Ronan, Lacout, Catherine, Auradé, Frédéric, Villeval, Jean-Luc, Gonin, Patrick, Vainchenker, William, Giraudier, Stéphane

“…Primary myelofibrosis (PMF) is the most serious myeloproliferative disorder, characterized by clonal myeloproliferation associated with cytokine-mediated bone…”
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Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling by Lordier, Larissa, Jalil, Abdelali, Aurade, Fréderic, Larbret, Fréderic, Larghero, Jerôme, Debili, Najet, Vainchenker, William, Chang, Yunhua

“…Megakaryocyte (MK) is the naturally polyploid cell that gives rise to platelets. Polyploidization occurs by endomitosis, which was a process considered to be…”
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N‐WASP is required for Amphiphysin‐2/BIN1‐dependent nuclear positioning and triad organization in skeletal muscle and is involved in the pathophysiology of centronuclear myopathy by Falcone, Sestina, Roman, William, Hnia, Karim, Gache, Vincent, Didier, Nathalie, Lainé, Jeanne, Auradé, Frederic, Marty, Isabelle, Nishino, Ichizo, Charlet‐Berguerand, Nicolas, Romero, Norma Beatriz, Marazzi, Giovanna, Sassoon, David, Laporte, Jocelyn, Gomes, Edgar

“…© 2014 The Authors. Published under the terms of the CC BY 4.0 license. This is an open access article under the terms of the Creative Commons Attribution 4.0…”
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The PAX-FOXO1s trigger fast trans-differentiation of chick embryonic neural cells into alveolar rhabdomyosarcoma with tissue invasive properties limited by S phase entry inhibition by Gonzalez Curto, Gloria, Der Vartanian, Audrey, Frarma, Youcef El-Mokhtar, Manceau, Line, Baldi, Lorenzo, Prisco, Selene, Elarouci, Nabila, Causeret, Frédéric, Korenkov, Daniil, Rigolet, Muriel, Aurade, Frédéric, De Reynies, Aurélien, Contremoulins, Vincent, Relaix, Frédéric, Faklaris, Orestis, Briscoe, James, Gilardi-Hebenstreit, Pascale, Ribes, Vanessa

“…The chromosome translocations generating PAX3-FOXO1 and PAX7-FOXO1 chimeric proteins are the primary hallmarks of the paediatric fusion-positive alveolar…”
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Obesity impairs skeletal muscle repair through NID-1 mediated extracellular matrix remodeling by mesenchymal progenitors by Pérez-Díaz, Sergio, Koumaiha, Zeynab, Borok, Matthew Jay, Aurade, Frederic, Pini, Maria, Periou, Baptiste, Rouault, Christine, Baba-Amer, Yasmine, Clément, Karine, Derumeaux, Genevieve, Authier, François Jérôme, Lafuste, Peggy, Relaix, Frederic

“…Obesity triggers skeletal muscle physio-pathological alterations. However, the crosstalk between adipose tissue and myogenic cells remains poorly understood…”
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A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes by Dos Santos, Matthieu, Backer, Stéphanie, Auradé, Frédéric, Wong, Matthew Man-Kin, Wurmser, Maud, Pierre, Rémi, Langa, Francina, Do Cruzeiro, Marcio, Schmitt, Alain, Concordet, Jean-Paul, Sotiropoulos, Athanassia, Jeffrey Dilworth, F., Noordermeer, Daan, Relaix, Frédéric, Sakakibara, Iori, Maire, Pascal

“…The contractile properties of adult myofibers are shaped by their Myosin heavy chain isoform content. Here, we identify by snATAC-seq a 42 kb super-enhancer at…”
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PAX3 Confers Functional Heterogeneity in Skeletal Muscle Stem Cell Responses to Environmental Stress by Der Vartanian, Audrey, Quétin, Marie, Michineau, Stéphanie, Auradé, Frédéric, Hayashi, Shinichiro, Dubois, Christelle, Rocancourt, Didier, Drayton-Libotte, Bernadette, Szegedi, Anikó, Buckingham, Margaret, Conway, Simon J., Gervais, Marianne, Relaix, Frédéric

“…Muscle satellite cells (MuSCs) are the quiescent muscle stem cells required for adult skeletal muscle repair. The impact of environmental stress such as…”
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Proplatelet formation is regulated by the Rho/ROCK pathway by Chang, Yunhua, Auradé, Frédéric, Larbret, Frédéric, Zhang, Yanyan, Le Couedic, Jean-Pierre, Momeux, Laurence, Larghero, Jerôme, Bertoglio, Jacques, Louache, Fawzia, Cramer, Elisabeth, Vainchenker, William, Debili, Najet

“…Platelets are released by megakaryocytes (MKs) via cytoplasmic extensions called proplatelets, which require profound changes in the microtubule and actin…”
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A de novo synonymous variant in EFTUD2 disrupts normal splicing and causes mandibulofacial dysostosis with microcephaly: case report by Jacob, Arthur, Pasquier, Jennifer, Carapito, Raphael, Auradé, Frédéric, Molitor, Anne, Froguel, Philippe, Fakhro, Khalid, Halabi, Najeeb, Viot, Géraldine, Bahram, Seiamak, Rafii, Arash

“…Mandibulofacial dysostosis with microcephaly (MFDM) is a rare autosomal dominant genetic disease characterized by intellectual and growth retardations, as well…”
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Antagonistic regulation of p57kip2 by Hes/Hey downstream of Notch signaling and muscle regulatory factors regulates skeletal muscle growth arrest by Zalc, Antoine, Hayashi, Shinichiro, Auradé, Frédéric, Bröhl, Dominique, Chang, Ted, Mademtzoglou, Despoina, Mourikis, Philippos, Yao, Zizhen, Cao, Yi, Birchmeier, Carmen, Relaix, Frédéric

“…A central question in development is to define how the equilibrium between cell proliferation and differentiation is temporally and spatially regulated during…”
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Generation of BAC Transgenic Tadpoles Enabling Live Imaging of Motoneurons by Using the Urotensin II-Related Peptide (ust2b) Gene as a Driver: e0117370 by Bougerol, Marion, Aurade, Frederic, Lambert, Francois M, Ray, Didier Le, Combes, Denis, Thoby-Brisson, Muriel, Relaix, Frederic, Pollet, Nicolas, Tostivint, Herve

“…Xenopus is an excellent tetrapod model for studying normal and pathological motoneuron ontogeny due to its developmental morpho-physiological advantages. In…”
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