Search Results - "Auperin, David D."

Concentration-dependent modulation of amyloid-beta in vivo and in vitro using the gamma-secretase inhibitor, LY-450139 by Lanz, Thomas A, Karmilowicz, Michael J, Wood, Kathleen M, Pozdnyakov, Nikolay, Du, Ping, Piotrowski, Mary A, Brown, Tracy M, Nolan, Charles E, Richter, Karl E G, Finley, James E, Fei, Qing, Ebbinghaus, Charles F, Chen, Yuhpyng L, Spracklin, Douglas K, Tate, Barbara, Geoghegan, Kieran F, Lau, Lit-Fui, Auperin, David D, Schachter, Joel B

“…LY-450139 is a gamma-secretase inhibitor shown to have efficacy in multiple cellular and animal models. Paradoxically, robust elevations of plasma amyloid-beta…”
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Design, synthesis, and in vivo characterization of a novel series of tetralin amino imidazoles as γ-secretase inhibitors: Discovery of PF-3084014 by Brodney, Michael A., Auperin, David D., Becker, Stacey L., Bronk, Brian S., Brown, Tracy M., Coffman, Karen J., Finley, James E., Hicks, Carol D., Karmilowicz, Michael J., Lanz, Thomas A., Liston, Dane, Liu, Xingrong, Martin, Barbara-Anne, Nelson, Robert B., Nolan, Charles E., Oborski, Christine E., Parker, Christine P., Richter, Karl E.G., Pozdnyakov, Nikolay, Sahagan, Barbara G., Schachter, Joel B., Sokolowski, Sharon A., Tate, Barbara, Wood, Douglas E., Wood, Kathleen M., Van Deusen, Jeffrey W., Zhang, Lei

“…A novel series of tetralin containing amino imidazoles, derived from modification of the corresponding phenyl acetic acid derivatives is described. Replacement…”
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Diamide amino-imidazoles: A novel series of γ-secretase inhibitors for the treatment of Alzheimer’s disease by Brodney, Michael A., Auperin, David D., Becker, Stacey L., Bronk, Brian S., Brown, Tracy M., Coffman, Karen J., Finley, James E., Hicks, Carol D., Karmilowicz, Michael J., Lanz, Thomas A., Liston, Dane, Liu, Xingrong, Martin, Barbara-Anne, Nelson, Robert B., Nolan, Charles E., Oborski, Christine E., Parker, Christine P., Richter, Karl E.G., Pozdnyakov, Nikolay, Sahagan, Barbara G., Schachter, Joel B., Sokolowski, Sharon A., Tate, Barbara, Van Deusen, Jeffrey W., Wood, Douglas E., Wood, Kathleen M.

“…The synthesis and structure–activity relationship (SAR) of a novel series of di-substituted imidazoles, derived from modification of DAPT, are described…”
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Simultaneous expression of the Lassa virus N and GPC genes from a single recombinant vaccinia virus by Morrison, H G, Goldsmith, C S, Regnery, H L, Auperin, D D

“…A new transfer vector was constructed that directs the insertion of two heterologous genes into the vaccinia virus thymidine kinase (TK) gene during a single…”
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Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines by Grissmer, S, Nguyen, A N, Aiyar, J, Hanson, D C, Mather, R J, Gutman, G A, Karmilowicz, M J, Auperin, D D, Chandy, K G

“…We have analyzed the biophysical and pharmacological properties of five cloned K+ (Kv) channels (Kv1.1, Kv1.2, Kv1.3, Kv1.5, and Kv3.1) stably expressed in…”
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Nucleotide Sequence Analyses and Predicted Coding of Bunyavirus Genome RNA Species by Clerx-van Haaster, C M, Akashi, H, Auperin, D D, Bishop, D H

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Sequence analysis of the Ebola virus genome: organization, genetic elements, and comparison with the genome of Marburg virus by Sanchez, A, Kiley, M P, Holloway, B P, Auperin, D D

“…Sequence analysis of the second through the sixth genes of the Ebola virus (EBO) genome indicates that it is organized similarly to rhabdoviruses and…”
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Nucleotide sequence of the Lassa virus (Josiah strain) S genome RNA and amino acid sequence comparison of the N and GPC proteins to other arenaviruses by Auperin, D D, McCormick, J B

“…The complete nucleotide sequence of the S genome RNA of the Josiah strain of Lassa virus was determined from cloned cDNA. The S RNA is 3402 nucleotides long…”
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Cross-protection against lymphocytic choriomeningitis virus mediated by a CD4+ T-cell clone specific for an envelope glycoprotein epitope of Lassa virus by LA POSTA, V. J, AUPERIN, D. D, KAMIN-LEWIS, R, COLE, G. A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Nucleotide sequence of the glycoprotein gene and intergenic region of the Lassa virus S genome RNA by Auperin, D D, Sasso, D R, McCormick, J B

“…Two overlapping cDNA clones corresponding to the 5' region of the Lassa virus S genome RNA were isolated and their nucleotide sequences determined. Similar to…”
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Protection of guinea pigs from Lassa fever by vaccinia virus recombinants expressing the nucleoprotein or the envelope glycoproteins of Lassa virus by Morrison, H G, Bauer, S P, Lange, J V, Esposito, J J, McCormick, J B, Auperin, D D

“…A recombinant vaccinia virus that expresses the nucleoprotein gene of Lassa virus (Josiah strain) under the control of the P7.5 promoter was constructed using…”
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The nucleoprotein gene of Ebola virus: cloning, sequencing, and in vitro expression by Sanchez, A, Kiley, M P, Holloway, B P, McCormick, J B, Auperin, D D

“…Genomic and messenger RNAs of a Zaire strain of Ebola virus were cloned, and inserts specific for the nucleoprotein gene were isolated and sequenced. The…”
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Production and characterization of guinea pig IL-5 in baculovirus-infected insect cells by Mansour, M, Karmilowicz, M, Hawrylik, S J, Nalcerio, B, Angilly, J, Conklyn, M J, Lilly, C M, Drazen, J M, Lee, S E, Auperin, D D, De Wet, J R, Cohan, V L, Showell, H J, Danley, D E

“…To study the role interleukin (IL)-5 may play in altering airway function in asthma, we have produced recombinant protein for exogenous administration to…”
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Baculovirus expression of the glycoprotein gene of Lassa virus and characterization of the recombinant protein by Hummel, K B, Martin, M L, Auperin, D D

“…A recombinant baculovirus was constructed that expresses the glycoprotein gene of Lassa virus (Josiah strain) under the transcriptional control of the…”
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Construction of a recombinant vaccinia virus expressing the Lassa virus glycoprotein gene and protection of guinea pigs from a lethal Lassa virus infection by Auperin, D D, Esposito, J J, Lange, J V, Bauer, S P, Knight, J, Sasso, D R, McCormick, J B

“…A cloned cDNA (1.65 kb) containing the complete glycoprotein gene of the Josiah strain of Lassa virus was inserted into the thymidine kinase (TK) gene of the…”
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Nucleotide sequence conservation at the 3' termini of the virion RNA species of New World and Old World arenaviruses by Auperin, D D, Compans, R W, Bishop, D H

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The sequences of the N protein gene and intergenic region of the S RNA of pichinde arenavirus by Auperin, D D, Galinski, M, Bishop, D H

“…Two overlapping DNA clones representing more than half of the Pichinde arenavirus S RNA segment were cloned into pBR322 and their nucleotide sequences were…”
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