Search Results - "Aupí, Miguel"
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Topical treatment with pterostilbene, a natural phytoalexin, effectively protects hairless mice against UVB radiation-induced skin damage and carcinogenesis
Published in Free radical biology & medicine (01-08-2015)“…The aim of our study was to investigate in the SKH-1 hairless mouse model the effect of pterostilbene (Pter), a natural dimethoxy analog of resveratrol (Resv),…”
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CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC
Published in Cancer research (Chicago, Ill.) (01-09-2019)“…Although EGFR mutant-selective tyrosine kinase inhibitors (TKI) are clinically effective, acquired resistance can occur by reactivating ERK. We show using…”
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7,8-hydroxy-2′-deoxyguanosine/2′-deoxiguanosine ratio determined in hydrolysates of brain DNA by ultrachromatrography coupled to tandem mass spectrometry
Published in Talanta (Oxford) (01-08-2017)“…7,8-hydroxy-2′-deoxyguanosine (8-OHdG) is an abundant DNA lesion formed by oxidation of the nucleoside 2’-deoxyguanosine (2-dG) and one of the most studied and…”
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Abstract LB-099: Metabolic vulnerabilities of mesenchymal-like EGFR-mutant NSCLC cells with acquired resistance to tyrosine kinase inhibitors
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Despite the availability of the effective targeted therapies in lung cancer, such as EGFR tyrosine kinase inhibitors (TKIs), drug tolerance and…”
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