Search Results - "Aung, Winn"

Near-infrared photoimmunotherapy of pancreatic cancer using an indocyanine green-labeled anti-tissue factor antibody by Aung, Winn, Tsuji, Atsushi B, Sugyo, Aya, Takashima, Hiroki, Yasunaga, Masahiro, Matsumura, Yasuhiro, Higashi, Tatsuya

“…To investigate near-infrared photoimmunotherapeutic effect mediated by an anti-tissue factor (TF) antibody conjugated to indocyanine green (ICG) in a…”
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Anti‑tissue factor antibody‑mediated immuno‑SPECT imaging of tissue factor expression in mouse models of pancreatic cancer by Sugyo, Aya, Aung, Winn, Tsuji, Atsushi B, Sudo, Hitomi, Takashima, Hiroki, Yasunaga, Masahiro, Matsumura, Yasuhiro, Saga, Tsuneo, Higashi, Tatsuya

“…Tissue factor (TF) has emerged as a critical factor in oncogenic events, leading to the development of TF‑targeted diagnostic and therapeutic approaches. A…”
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Folate receptor-targeted near-infrared photodynamic therapy for folate receptor-overexpressing tumors by Aung, Winn, Tsuji, Atsushi B, Hanaoka, Kenjiro, Higashi, Tatsuya

“…Photodynamic therapy (PDT) is a minimally invasive form of cancer therapy, and the development of a novel photosensitizer (PS) with optimal properties is…”
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Combined treatment of pancreatic cancer xenograft with 90Y-ITGA6B4-mediated radioimmunotherapy and PI3K/mTOR inhibitor by Aung, Winn, Tsuji, Atsushi B, Sudo, Hitomi, Sugyo, Aya, Ukai, Yoshinori, Kouda, Katsushi, Kurosawa, Yoshikazu, Furukawa, Takako, Saga, Tsuneo, Higashi, Tatsuya

“…AIMTo investigate the therapeutic effect of combined integrin α6β4-targeted radioimmunotherapy (RIT) and PI3K/mTOR inhibitor BEZ235 in a pancreatic cancer…”
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Anticancer Effect of Dihydroartemisinin (DHA) in a Pancreatic Tumor Model Evaluated by Conventional Methods and Optical Imaging by WINN AUNG, SOGAWA, Chizuru, FURUKAWA, Takako, SAGA, Tsuneo

“…Dihydroartemisinin (DHA) inhibits the growth of certain cancer cells and xenograft tumors. Further understanding of the molecular mechanisms and genetic…”
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Quantitative Radionuclide Imaging Analysis of Enhanced Drug Delivery Induced by Photoimmunotherapy by Aung, Winn, Tsuji, Atsushi B., Sugyo, Aya, Fujinaga, Masayuki, Zhang, Ming-Rong, Higashi, Tatsuya

“…Photoimmunotherapy (PIT) is an upcoming potential cancer treatment modality, the effect of which is improved in combination with chemotherapy. PIT causes a…”
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Radioimmunotherapy of pancreatic cancer xenografts in nude mice using 90Y-labeled anti-α6β4 integrin antibody by Aung, Winn, Tsuji, Atsushi B, Sudo, Hitomi, Sugyo, Aya, Ukai, Yoshinori, Kouda, Katsushi, Kurosawa, Yoshikazu, Furukawa, Takako, Saga, Tsuneo

“…The contribution of integrin α6β4 (α6β4) overexpression to the pancreatic cancer invasion and metastasis has been previously shown. We have reported…”
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Diffusion coefficients in abdominal organs and hepatic lesions: evaluation with intravoxel incoherent motion echo-planar MR imaging by Yamada, I, Aung, W, Himeno, Y, Nakagawa, T, Shibuya, H

“…To determine the true diffusion coefficients of abdominal organs and hepatic lesions with intravoxel incoherent motion (IVIM) echo-planar magnetic resonance…”
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Immunotargeting of Integrin α6β4 for Single-Photon Emission Computed Tomography and Near-Infrared Fluorescence Imaging in a Pancreatic Cancer Model by Aung, Winn, Tsuji, Atsushi B., Sudo, Hitomi, Sugyo, Aya, Furukawa, Takako, Ukai, Yoshinori, Kurosawa, Yoshikazu, Saga, Tsuneo

“…To explore suitable imaging probes for early and specific detection of pancreatic cancer, we demonstrated that α6β4 integrin is a good target and employed…”
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Potential role of ferritin heavy chain in oxidative stress and apoptosis in human mesothelial and mesothelioma cells: implications for asbestos-induced oncogenesis by Aung, Winn, Hasegawa, Sumitaka, Furukawa, Takako, Saga, Tsuneo

“…Exposure to asbestos is a known etiological factor in malignant mesothelioma (MM). However, in vitro cell culture studies have provided paradoxical evidence…”
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Basic Studies on Radioimmunotargeting of CD133-Positive HCT116 Cancer Stem Cells by Jin, Zhao-Hui, Sogawa, Chizuru, Furukawa, Takako, Saito, Yuriko, Aung, Winn, Fujibayashi, Yasuhisa, Saga, Tsuneo

“…As cancer stem cells (CSCs) are postulated to play critical roles in cancer development, including metastasis and recurrence, CSC imaging would provide…”
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A limited overlap between intratumoral distribution of 1-(5-fluoro-5-deoxy-α-D-arabinofuranosyl)-2-nitroimidazole and copper-diacetyl-bis[N(4)-methylthiosemicarbazone] by FURUKAWA, TAKAKO, YUAN, QINGHUA, JIN, ZHAO-HUI, AUNG, WINN, YOSHII, YUKIE, HASEGAWA, SUMITAKA, ENDO, HIROKO, INOUE, MASAHIRO, ZHANG, MING-RONG, FUJIBAYASHI, YASUHISA, SAGA, TSUNEO

“…Positron emission tomography (PET) imaging of tumor hypoxia provides valuable information for cancer treatment planning. Two types of PET tracers,…”
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C-Type Natriuretic Peptide Specifically Acts on the Pylorus and Large Intestine in Mouse Gastrointestinal Tract by Sogawa, Chizuru, Wakizaka, Hidekatsu, Aung, Winn, Jin, Zhao-hui, Tsuji, Atsushi B, Furukawa, Takako, Kunieda, Tetsuo, Saga, Tsuneo

“…C-type natriuretic peptide (CNP) exerts its main biological effects by binding to natriuretic peptide receptor B (NPR-B), a membrane-bound guanylyl cyclase…”
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Comparison of intratumoral FDG and Cu-ATSM distributions in cancer tissue originated spheroid (CTOS) xenografts, a tumor model retaining the original tumor properties by Furukawa, Takako, Yuan, Qinghua, Jin, Zhao-Hui, Aung, Winn, Yoshii, Yukie, Hasegawa, Sumitaka, Endo, Hiroko, Inoue, Masahiro, Zhang, Ming-Rong, Fujibayashi, Yasuhisa, Saga, Tsuneo

“…Abstract Introduction The intratumoral distributions of [18 F]FDG and [64 Cu]Cu-ATSM have been reported to be similar in adenocarcinomas but different in…”
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Visualization of in vivo electroporation-mediated transgene expression in experimental tumors by optical and magnetic resonance imaging by Aung, W, Hasegawa, S, Koshikawa-Yano, M, Obata, T, Ikehira, H, Furukawa, T, Aoki, I, Saga, T

“…In vivo electroporation (EP) is an efficient method for effective gene transfer and is highly expected for application in anticancer gene therapy. Non-invasive…”
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Immuno-PET Imaging of HER3 in a Model in which HER3 Signaling Plays a Critical Role by Yuan, Qinghua, Furukawa, Takako, Tashiro, Takahiro, Okita, Kouki, Jin, Zhao-Hui, Aung, Winn, Sugyo, Aya, Nagatsu, Kotaro, Endo, Hiroko, Tsuji, Atsushi B, Zhang, Ming-Rong, Masuko, Takashi, Inoue, Masahiro, Fujibayashi, Yasuhisa, Saga, Tsuneo

“…HER3 is overexpressed in various carcinomas including colorectal cancer (CRC), which is associated with poor prognosis, and is involved in the development of…”
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Comparison of stable nitroxide, 3-substituted 2,2,5,5-tetramethylpyrrolidine- N-oxyls, with respect to protection from radiation, prevention of DNA damage, and distribution in mice by Anzai, Kazunori, Ueno, Megumi, Yoshida, Akira, Furuse, Masako, Aung, Winn, Nakanishi, Ikuo, Moritake, Takashi, Takeshita, Keizo, Ikota, Nobuo

“…We compared three 3-substituted 2,2,5,5-tetramethylpyrrolidine- N-oxyls (PROXYLs): carbamoyl-, methoxycarbonyl-, and hydroxymethyl-PROXYL (CM-, MC-, and…”
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Study of Quantitative Oral Radioactivity in Salivary Gland Scintigraphy and Determination of the Clinical Stage of Sjogren's Syndrome by Aung, Winn, Murata, Yuji, Ishida, Ryuji, Takahashi, Yuzo, Okada, Norihiko, Shibuya, Hitoshi

“…In this study, the oral radioactivity seen in salivary gland scintigraphy, which was established entirely on the basis of radioactive saliva secreted by the…”
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Noninvasive assessment of regulable transferred-p53 gene expression and evaluation of therapeutic response with FDG-PET in tumor model by Aung, W, Hasegawa, S, Koshikawa-Yano, M, Tsuji, A B, Sogawa, C, Sudo, H, Sugyo, A, Koizumi, M, Furukawa, T, Saga, T

“…The use of tumor-suppressor gene p53 as an anticancer therapeutic has been vigorously investigated. However, progress has met with limited success to date…”
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Sjogren's Syndrome: Comparison of Assessments with Quantitative Salivary Gland Scintigraphy and Contrast Sialography by Aung, Winn, Yamada, Ichiro, Umehara, Isao, Ohbayashi, Naoto, Yoshino, Norio, Shibuya, Hitoshi

“…This study compared the quantitative parameters of salivary gland scintigraphy and the sialographic stages in patients with Sjögren's syndrome. One hundred…”
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