Search Results - "Aumeier, Charlotte"
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Lattice defects induce microtubule self-renewal
Published in Nature physics (01-08-2019)“…Microtubules are dynamic polymers, which grow and shrink by addition and removal of tubulin dimers at their extremities. Within the microtubule shaft, dimers…”
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2
Kinesin-1 activity recorded in living cells with a precipitating dye
Published in Nature communications (05-03-2021)“…Kinesin-1 is a processive motor protein that uses ATP-derived energy to transport a variety of intracellular cargoes toward the cell periphery. The ability to…”
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3
Microtubule damage shapes the acetylation gradient
Published in Nature communications (06-03-2024)“…The properties of single microtubules within the microtubule network can be modulated through post-translational modifications (PTMs), including acetylation…”
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4
Self-repair protects microtubules from destruction by molecular motors
Published in Nature materials (01-06-2021)“…Microtubule instability stems from the low energy of tubulin dimer interactions, which sets the growing polymer close to its disassembly conditions. Molecular…”
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5
Two-color in vitro assay to visualize and quantify microtubule shaft dynamics
Published in STAR protocols (17-06-2022)“…Microtubules are dynamic polymers where tubulin exchanges not only at the ends but also all along the microtubule shaft. In vitro reconstitutions are a vital…”
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6
Cell scientist to watch – Charlotte Aumeier
Published in Journal of cell science (01-10-2023)“…ABSTRACT Charlotte Aumeier is an Assistant Professor of Biochemistry at the University of Geneva, Switzerland. After completing her PhD at the University of…”
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Toward a Traceless Tag for the Thiol‐Mediated Uptake of Proteins
Published in ChemistryEurope (01-11-2023)“…The emergence of thiol‐mediated uptake (TMU) as a powerful strategy to penetrate cells calls for the development of practical small‐molecule TMU tools for…”
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8
A liquid +TIP-network drives microtubule dynamics through tubulin condensation
Published in Biophysical journal (11-02-2022)Get full text
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9
Regulation of the microtubule network; the shaft matters
Published in Current opinion in systems biology (01-06-2023)“…In cells, the microtubule network continually assembles and disassembles. The regulation of microtubule growth or shortening has almost exclusively been…”
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10
Self-repair promotes microtubule rescue
Published in Nature cell biology (01-10-2016)“…The dynamic instability of microtubules is characterized by slow growth phases stochastically interrupted by rapid depolymerizations called catastrophes…”
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11
Motor usage imprints microtubule stability along the shaft
Published in Developmental cell (10-01-2022)“…Tubulin dimers assemble into dynamic microtubules, which are used by molecular motors as tracks for intracellular transport. Organization and dynamics of the…”
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12
Phase separation of +TIP networks regulates microtubule dynamics
Published in Proceedings of the National Academy of Sciences - PNAS (29-08-2023)“…Regulation of microtubule dynamics is essential for diverse cellular functions, and proteins that bind to dynamic microtubule ends can regulate network…”
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13
The effect of motor-induced shaft dynamics on microtubule stability and length
Published in Biophysical journal (17-01-2023)“…Control of microtubule abundance, stability, and length is crucial to regulate intracellular transport as well as cell polarity and division. How microtubule…”
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14
Microtubule shaft integrity emerges as a crucial determinant of the acetylation pattern
Published in Cytoskeleton (Hoboken, N.J.) (24-06-2024)Get full text
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15
Tubulin engineering by semi-synthesis reveals that polyglutamylation directs detyrosination
Published in Nature chemistry (01-08-2023)“…Microtubules, a critical component of the cytoskeleton, carry post-translational modifications (PTMs) that are important for the regulation of key cellular…”
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16
Self-repair protects microtubules from their destruction by molecular motors
Published in Nature materials (21-01-2021)“…Microtubule instability stems from the low energy of tubulin dimer interactions, which sets the growing polymer close to its disassembly conditions. Molecular…”
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17
Actin, actin-related proteins and profilin in diatoms: A comparative genomic analysis
Published in Marine genomics (01-10-2015)“…Diatoms are heterokont unicellular algae with a widespread distribution throughout all aquatic habitats. Research on diatoms has advanced significantly over…”
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