Search Results - "Aukema, HM"

Cyclooxygenase (COX) Derived Oxylipins are Elevated in Models of Polycystic Kidney Disease, Indicating Potential for COX Inhibition to Treat Disease by Monirujjaman, Md, Devassy, JG, Yamaguchi, T, Gabbs, Melissa, Winter, Tanja, Ravandi, A, Aukema, HM

“…Abstract only Background Oxylipins (e.g. prostaglandins, leukotrienes) are bioactive lipids formed via oxidative metabolism of polyunsaturated fatty acids. The…”
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Dietary conjugated linoleic acid reduces PGE release and interstitial injury in rat polycystic kidney disease

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Selectivity of cyclooxygenase isoform activity and prostanoid production in normal and diseased Han:SPRD-cy rat kidneys by Warford-Woolgar, Lori, Peng, Claudia Yu-Chen, Shuhyta, Jamie, Wakefield, Andrew, Sankaran, Deepa, Ogborn, Malcolm, Aukema, Harold M

“…Renal prostanoids are important regulators of normal renal function and maintenance of renal homeostasis. In diseased kidneys, renal cylooxygenase (COX)…”
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Dietary soy protein effects on disease and IGF-I in male and female Han:SPRD-cy rats by Aukema, Harold M., Housini, Ihsan

“…Dietary soy protein effects on disease and IGF-I in male and female Han:SPRD-cy rats. Dietary soy protein compared with casein retards disease progression in a…”
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Dietary soy protein attenuates renal disease progression after 1 and 3 weeks in Han:SPRD-cy weanling rats by Fair, Denise E, Ogborn, Malcolm R, Weiler, Hope A, Bankovic-Calic, Neda, Nitschmann, Evan P, Fitzpatrick-Wong, Shirley C, Aukema, Harold M

“…Compared with casein, dietary soy protein slows disease progression in animal models of chronic renal injury. To determine whether dietary soy protein feeding…”
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Detrimental effects of a high fat diet in early renal injury are ameliorated by fish oil in Han:SPRD-cy rats by Lu, Jing, Bankovic-Calic, Neda, Ogborn, Malcolm, Saboorian, M Hossein, Aukema, Harold M

“…Dietary fish oils containing (n-3) fatty acids can modulate renal inflammatory injury. We previously demonstrated that a high fat (HF) diet worsens early renal…”
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Modulation of renal injury in pcy mice by dietary fat containing n-3 fatty acids depends on the level and type of fat by Sankaran, D, Lu, J, Bankovic-Calic, N, Ogborn, M.R, Aukema, H.M

“…Low‐fat diets and diets containing n−3 fatty acids (FA) slow the progression of renal injury in the male Han:Sprague‐Dawley (SPRD)‐cy rat model of polycystic…”
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Dietary soy protein effects on inherited polycystic kidney disease are influenced by gender and protein level by AUKEMA, H. M, HOUSINI, I, RAWLING, J. M

“…The effects of dietary soy protein compared to casein were examined in male and female CD1-pcy/pcy (pcy) mice with polycystic kidney disease. Animals 10 wk of…”
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脂肪と食物繊維摂取がラットの大腸がんの増大における細胞内のセカンドメッセンジャーを変える by Jiang YH, Lupton JR, Chang WCL, Jolly CA, Aukema HM, Chapkin RS

“…脂肪, 食物繊維と発がん物質による大腸の上皮細胞内のセカンドメッセンジャーである1, 2-diacyl-sn-glycerol(DAG), ceramide, phospholipase C(PLC-gamma 1)に対する影響を雄のラット(Sprague-Dawley)160匹(1群当り10匹)で検討…”
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Creatine Supplementation Increases Renal Disease Progression in Han:SPRD-cy Rats by Edmunds, Jeff W., Jayapalan, Shobana, DiMarco, Nancy M., Saboorian, Houssein, Aukema, Harold M.

“…The growing use of creatine as a potential ergogenic aid among active individuals has raised concern regarding its effects on the kidney, particularly among…”
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High dietary fat intake increases renal cyst disease progression in Han:SPRD-cy rats by Jayapalan, S, Saboorian, M H, Edmunds, J W, Aukema, H M

“…The effect of a high level of dietary fat on renal cyst disease was examined in the Han:SPRD-cy rat model of polycystic kidney disease. Control and diseased…”
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Protein kinase C isoforms in human and rat colonic mucosa by Davidson, L A, Jiang, Y H, Derr, J N, Aukema, H M, Lupton, J R, Chapkin, R S

“…The protein kinase C (PKC) family of enzymes plays a key role in the regulation of cellular events, including cell proliferation and differentiation. Work from…”
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Early dietary protein restriction slows disease progression and lengthens survival in mice with polycystic kidney disease by Tomobe, K, Philbrick, D, Aukema, H M, Clark, W F, Ogborn, M R, Parbtani, A, Takahashi, H, Holub, B J

“…The objective of these studies was to examine the effects of early dietary protein restriction on disease progression and survival in the DBA/2FG-pcy (pcy)…”
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Safety of chronic exercise in a rat model of kidney disease by DARNLEY, M. J, DIMARCO, N. M, AUKEMA, H. M

“…The objective of this study was to determine the effect of treadmill running on polycystic kidney disease (PKD) progression and bone mineral density in…”
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Dietary fat and fiber alter rat colonic mucosal lipid mediators and cell proliferation by Lee, D Y, Lupton, J R, Aukema, H M, Chapkin, R S

“…To better understand the biochemical mechanisms by which dietary fat and fiber modulate colonic cell proliferation, we determined the effect of dietary fats…”
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Dietary fat and fiber differentially alter intracellular second messengers during tumor development in rat colon by Jiang, Y H, Lupton, J R, Chang, W C, Jolly, C A, Aukema, H M, Chapkin, R S

“…The effect of fat, fiber and carcinogen on colonic epithelial intracellular second messengers 1,2-diacyl-sn-glycerol (DAG), ceramide, and the steady-state…”
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Butyrate alters activity of specific cAMP-receptor proteins in a transgenic mouse colonic cell line by Aukema, H M, Davidson, L A, Pence, B C, Jiang, Y H, Lupton, J R, Chapkin, R S

“…There is great interest in utilizing butyrate as a chemotherapeutic agent. To elucidate its mechanism of action, the effect of butyrate on cAMP receptor…”
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Dietary fat and fiber alter rat colonic protein kinase C isozyme expression by Davidson, L A, Lupton, J R, Jiang, Y H, Chang, W C, Aukema, H M, Chapkin, R S

“…To better understand the biochemical mechanisms by which select fats and fibers modulate colonic cell proliferation, we determined the profile of protein…”
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Effects of dietary protein restriction and oil type on the early progression of murine polycystic kidney disease by Aukema, Harold M., Ogborn, Malcolm R., Tomobe, Koji, Takahashi, Hisahide, Hibino, Tsutomu, Holub, Bruce J.

“…Effects of dietary protein restriction and oil type on the early progression of murine polycystic kidney disease. A paucity of research data exists on the…”
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Effect of dietary supplementation with a fish oil concentrate on the alkenylacyl class of ethanolamine phospholipid in human platelets by Aukema, H M, Holub, B J

“…It has been demonstrated that the alkenylacyl class of ethanolamine phospholipid (PE) represents one of the major forms of eicosapentaenoic acid…”
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