Search Results - "Augustine, GJ"

Structural Domains Involved in the Regulation of Transmitter Release by Synapsins by Hilfiker, Sabine, Benfenati, Fabio, Doussau, Frederic, Nairn, Angus C, Czernik, Andrew J, Augustine, George J, Greengard, Paul

“…Synapsins are a family of neuron-specific phosphoproteins that regulate neurotransmitter release by associating with synaptic vesicles. Synapsins consist of a…”
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Synaptic Connectivity between the Cortex and Claustrum Is Organized into Functional Modules by Chia, Zach, Augustine, George J., Silberberg, Gilad

“…The widespread reciprocal connectivity between the claustrum and the neocortex has stimulated numerous hypotheses regarding its function; all of these suggest…”
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Structural basis for delta cell paracrine regulation in pancreatic islets by Arrojo e Drigo, Rafael, Jacob, Stefan, García-Prieto, Concha F., Zheng, Xiaofeng, Fukuda, Masahiro, Nhu, Hoa Tran Thi, Stelmashenko, Olga, Peçanha, Flavia Letícia Martins, Rodriguez-Diaz, Rayner, Bushong, Eric, Deerinck, Thomas, Phan, Sebastien, Ali, Yusuf, Leibiger, Ingo, Chua, Minni, Boudier, Thomas, Song, Sang-Ho, Graf, Martin, Augustine, George J., Ellisman, Mark H., Berggren, Per-Olof

“…Little is known about the role of islet delta cells in regulating blood glucose homeostasis in vivo. Delta cells are important paracrine regulators of beta…”
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Local Calcium Signaling in Neurons by Augustine, George J, Santamaria, Fidel, Tanaka, Keiko

“…Transient rises in the cytoplasmic concentration of calcium ions serve as second messenger signals that control many neuronal functions. Selective triggering…”
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Pharmacologically Distinct Presynaptic Calcium Channels in Cerebellar Excitatory and Inhibitory Synapses by DOROSHENKO, P.A, WOPPMANN, A, MILJANICH, G, AUGUSTINE, G.J

“…We have used whole-cell patch clamp recordings and pharmacological blockers of Ca channels to compare the pharmacology of Ca channels that mediate synaptic…”
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How does calcium trigger neurotransmitter release? by Augustine, George J

“…Recent work has established that different geometric arrangements of calcium channels are found at different presynaptic terminals, leading to a wide spectrum…”
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A Genetically Encoded Ratiometric Indicator for Chloride: Capturing Chloride Transients in Cultured Hippocampal Neurons by Kuner, Thomas, Augustine, George J.

“…We constructed a novel optical indicator for chloride ions by fusing the chloride-sensitive yellow fluorescent protein with the chloride-insensitive cyan…”
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Alien intracellular calcium chelators attenuate neurotransmitter release at the squid giant synapse by Adler, EM, Augustine, GJ, Duffy, SN, Charlton, MP

“…A number of calcium buffers were examined for their ability to reduce evoked transmitter release when injected into the presynaptic terminal of the squid giant…”
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Different Presynaptic Roles of Synapsins at Excitatory and Inhibitory Synapses by Gitler, Daniel, Takagishi, Yoshiko, Feng, Jian, Ren, Yong, Rodriguiz, Ramona M, Wetsel, William C, Greengard, Paul, Augustine, George J

“…The functions of synapsins were examined by characterizing the phenotype of mice in which all three synapsin genes were knocked out. Although these triple…”
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The Primordial, Blue-Cone Color System of the Mouse Retina by Haverkamp, Silke, Wassle, Heinz, Duebel, Jens, Kuner, Thomas, Augustine, George J, Feng, Guoping, Euler, Thomas

“…Humans and old world primates have trichromatic color vision based on three spectral types of cone [long-wavelength (L-), middle-wavelength (M-), and…”
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Synaptotagmin I Synchronizes Transmitter Release in Mouse Hippocampal Neurons by Nishiki, Tei-ichi, Augustine, George J

“…We have asked whether loss of the Ca2+ sensor protein synaptotagmin I influences the total amount of neurotransmitter released after a presynaptic action…”
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Pancreatic Islet Blood Flow Dynamics in Primates by Diez, Juan A., Arrojo e Drigo, Rafael, Zheng, Xiaofeng, Stelmashenko, Olga V., Chua, Minni, Rodriguez-Diaz, Rayner, Fukuda, Masahiro, Köhler, Martin, Leibiger, Ingo, Tun, Sai Bo Bo, Ali, Yusuf, Augustine, George J., Barathi, Veluchamy A., Berggren, Per-Olof

“…Blood flow regulation in pancreatic islets is critical for function but poorly understood. Here, we establish an in vivo imaging platform in a non-human…”
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Cocaine Increases Dopamine Release by Mobilization of a Synapsin-Dependent Reserve Pool by Venton, B. Jill, Seipel, Andrew T, Phillips, Paul E. M, Wetsel, William C, Gitler, Daniel, Greengard, Paul, Augustine, George J, Wightman, R. Mark

“…Cocaine primarily exerts its behavioral effects by enhancing dopaminergic neurotransmission, amplifying dopamine-encoded sensorimotor integration. The presumed…”
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Dual Roles of the C2B Domain of Synaptotagmin I in Synchronizing Ca2+-Dependent Neurotransmitter Release by Nishiki, Tei-ichi, Augustine, George J

“…Although the vesicular protein synaptotagmin I contains two Ca2+-binding domains (C2A and C2B), Ca2+ binding to the C2B domain is more important for triggering…”
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Two-Photon Imaging Reveals Somatodendritic Chloride Gradient in Retinal ON-Type Bipolar Cells Expressing the Biosensor Clomeleon by Duebel, Jens, Haverkamp, Silke, Schleich, Wolfram, Feng, Guoping, Augustine, George J., Kuner, Thomas, Euler, Thomas

“…A somatodendritic gradient of Cl − concentration ([Cl −] i) has been postulated to generate GABA-evoked responses of different polarity in retinal bipolar…”
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Heterogeneous somatostatin-expressing neuron population in mouse ventral tegmental area by Nagaeva, Elina, Zubarev, Ivan, Bengtsson Gonzales, Carolina, Forss, Mikko, Nikouei, Kasra, de Miguel, Elena, Elsilä, Lauri, Linden, Anni-Maija, Hjerling-Leffler, Jens, Augustine, George J, Korpi, Esa R

“…The cellular architecture of the ventral tegmental area (VTA), the main hub of the brain reward system, remains only partially characterized. To extend the…”
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The Chloride Transporter Na+-K+-Cl- Cotransporter Isoform-1 Contributes to Intracellular Chloride Increases after In Vitro Ischemia by Pond, Brooks B, Berglund, Ken, Kuner, Thomas, Feng, Guoping, Augustine, George J, Schwartz-Bloom, Rochelle D

“…Ischemic episodes in the CNS cause significant disturbances in neuronal ionic homeostasis. To directly measure changes in intracellular Cl- concentration…”
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Local calcium signalling by inositol-1,4,5-trisphosphate in Purkinje cell dendrites by Augustine, George J, Finch, Elizabeth A

“…The second messenger inositol-1,4,5-trisphosphate (InsP3) releases Ca2+ from intracellular Ca2+ stores by activating specific receptors on the membranes of…”
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Author Correction: Structural basis for delta cell paracrine regulation in pancreatic islets by e Drigo, Rafael Arrojo, Jacob, Stefan, García-Prieto, Concha F., Zheng, Xiaofeng, Fukuda, Masahiro, Nhu, Hoa Tran Thi, Stelmashenko, Olga, Peçanha, Flavia Letícia Martins, Rodriguez-Diaz, Rayner, Bushong, Eric, Deerinck, Thomas, Phan, Sebastien, Ali, Yusuf, Leibiger, Ingo, Chua, Minni, Boudier, Thomas, Song, Sang-Ho, Graf, Martin, Augustine, George J., Ellisman, Mark H., Berggren, Per-Olof

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Synapsins as regulators of neurotransmitter release by Hilfiker, Sabine, Pieribone, Vincent A., Czernik, Andrew J., Kao, Hung-Teh, Augustine, George J., Greengard, Paul

“…One of the crucial issues in understanding neuronal transmission is to define the role(s) of the numerous proteins that are localized within presynaptic…”
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