Search Results - "Augustin, René"
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Bacteria–bacteria interactions within the microbiota of the ancestral metazoan Hydra contribute to fungal resistance
Published in The ISME Journal (01-07-2015)“…Epithelial surfaces of most animals are colonized by diverse microbial communities. Although it is generally agreed that commensal bacteria can serve…”
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More than just orphans: are taxonomically-restricted genes important in evolution?
Published in Trends in genetics (01-09-2009)“…Comparative genome analyses indicate that every taxonomic group so far studied contains 10–20% of genes that lack recognizable homologs in other species. Do…”
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A secreted antibacterial neuropeptide shapes the microbiome of Hydra
Published in Nature communications (26-09-2017)“…Colonization of body epithelial surfaces with a highly specific microbial community is a fundamental feature of all animals, yet the underlying mechanisms by…”
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Spontaneous body contractions are modulated by the microbiome of Hydra
Published in Scientific reports (21-11-2017)“…Spontaneous contractile activity, such as gut peristalsis, is ubiquitous in animals and is driven by pacemaker cells. In humans, disruption of the contraction…”
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In an early branching metazoan, bacterial colonization of the embryo is controlled by maternal antimicrobial peptides
Published in Proceedings of the National Academy of Sciences - PNAS (19-10-2010)“…Early embryos of many organisms develop outside the mother and are immediately confronted with myriads of potential colonizers. How these naive developmental…”
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The dynamic genome of Hydra
Published in Nature (London) (25-03-2010)“…The freshwater cnidarian Hydra was first described in 1702 and has been the object of study for 300 years. Experimental studies of Hydra between 1736 and 1744…”
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Activity of the Novel Peptide Arminin against Multiresistant Human Pathogens Shows the Considerable Potential of Phylogenetically Ancient Organisms as Drug Sources
Published in Antimicrobial Agents and Chemotherapy (01-12-2009)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Shaping the microenvironment: evidence for the influence of a host galaxin on symbiont acquisition and maintenance in the squid-vibrio symbiosis
Published in Environmental microbiology (01-12-2014)“…Summary Most bacterial species make transitions between habitats, such as switching from free living to symbiotic niches. We provide evidence that a galaxin…”
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The dual nature of haemocyanin in the establishment and persistence of the squid–vibrio symbiosis
Published in Proceedings of the Royal Society. B, Biological sciences (22-06-2014)“…We identified and sequenced from the squid Euprymna scolopes two isoforms of haemocyanin that share the common structural/physiological characteristics of…”
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Initial Symbiont Contact Orchestrates Host-Organ-wide Transcriptional Changes that Prime Tissue Colonization
Published in Cell host & microbe (14-08-2013)“…Upon transit to colonization sites, bacteria often experience critical priming that prepares them for subsequent, specific interactions with the host; however,…”
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How do environmental factors influence life cycles and development? An experimental framework for early‐diverging metazoans
Published in BioEssays (01-12-2014)“…Ecological developmental biology (eco‐devo) explores the mechanistic relationships between the processes of individual development and environmental factors…”
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Uncovering the evolutionary history of innate immunity: The simple metazoan Hydra uses epithelial cells for host defence
Published in Developmental and comparative immunology (01-04-2009)“…Although many properties of the innate immune system are shared among multicellular animals, the evolutionary origin remains poorly understood. Here we…”
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Identification of a kazal-type serine protease inhibitor with potent anti-staphylococcal activity as part of Hydra's innate immune system
Published in Developmental and comparative immunology (01-07-2009)“…In the absence of migratory phagocytic cells the basal metazoan Hydra has developed a very effective immune system. Previous work has shown that epithelial…”
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Hydramacin-1, Structure and Antibacterial Activity of a Protein from the Basal Metazoan Hydra
Published in The Journal of biological chemistry (16-01-2009)“…Hydramacin-1 is a novel antimicrobial protein recently discovered during investigations of the epithelial defense of the ancient metazoan Hydra. The amino acid…”
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How Hydra senses and destroys microbes
Published in Seminars in immunology (01-02-2010)“…Abstract Molecular genetic evidence has revealed that the basic templates of innate immune sensors were laid down in ancient animals such as the cnidarian…”
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Dickkopf related genes are components of the positional value gradient in Hydra
Published in Developmental biology (01-08-2006)“…Hydra is a classical model organism to understand fundamental developmental biological processes such as regeneration and axis formation. Here, we show that…”
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Embryo protection in contemporary immunology: Why bacteria matter
Published in Communicative & integrative biology (01-07-2011)“…Early embryos of many vertebrates and invertebrates develop outside the mother and are exposed to myriads of potential microbial colonizers. Here we discuss…”
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Cnidarian immunity: a tale of two barriers
Published in Advances in experimental medicine and biology (2010)“…The phylum Cnidariais one of the earliest branches in the animal tree of life providing crucial insights into the early evolution of immunity. The diversity in…”
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Where simplicity meets complexity: hydra, a model for host-microbe interactions
Published in Advances in experimental medicine and biology (01-01-2012)“…For a long time, the main purpose of microbiology and immunology was to study pathogenic bacteria and infectious disease; the potential benefit of commensal…”
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Das Prinzip Metaorganismus
Published in Biospektrum (01-10-2011)“…Zusammenfassung Alle vielzelligen Organismen sind dauerhaft mit Mikroben assoziiert und daher Metaorganismen. Einfache Modellsysteme wie Hydra erlauben es, die…”
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