Search Results - "August, Avery"

ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells by Huang, Weishan, Solouki, Sabrina, Koylass, Nicholas, Zheng, Song-Guo, August, Avery

“…Type 1 regulatory T (Tr1) cells differentiate in response to signals engaging the T cell receptor (TCR), express high levels of the immunosuppressive cytokine…”
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A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic by Shapira, Tirosh, Monreal, I. Abrrey, Dion, Sébastien P., Buchholz, David W., Imbiakha, Brian, Olmstead, Andrea D., Jager, Mason, Désilets, Antoine, Gao, Guang, Martins, Mathias, Vandal, Thierry, Thompson, Connor A. H., Chin, Aaleigha, Rees, William D., Steiner, Theodore, Nabi, Ivan Robert, Marsault, Eric, Sahler, Julie, Diel, Diego G., Van de Walle, Gerlinde R., August, Avery, Whittaker, Gary R., Boudreault, Pierre-Luc, Leduc, Richard, Aguilar, Hector C., Jean, François

“…The COVID-19 pandemic caused by the SARS-CoV-2 virus remains a global public health crisis. Although widespread vaccination campaigns are underway, their…”
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Konjac Glucomannan Oligosaccharides Prevent Intestinal Inflammation Through SIGNR1‐Mediated Regulation of Alternatively Activated Macrophages by Tang, Jiqing, Liu, Jun, Yan, Qiaojuan, Gu, Zhenglong, August, Avery, Huang, Weishan, Jiang, Zhengqiang

“…Scope Konjac glucomannan oligosaccharides (KMOS) are prebiotics and may improve intestinal immunity through modulation of macrophage function. However, the…”
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Circulating microRNAs as biomarkers in patients with allergic rhinitis and asthma by Panganiban, Ronaldo P., BS, Wang, Yanli, BS, Howrylak, Judie, MD, PhD, Chinchilli, Vernon M., PhD, Craig, Timothy J., DO, August, Avery, PhD, Ishmael, Faoud T., MD, PhD

“…Background MicroRNAs (miRNAs) are emerging as important regulatory molecules that might be involved in the pathogenesis of various diseases. Circulating miRNAs…”
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Thymic regulatory T cells arise via two distinct developmental programs by Owen, David L., Mahmud, Shawn A., Sjaastad, Louisa E., Williams, Jason B., Spanier, Justin A., Simeonov, Dimitre R., Ruscher, Roland, Huang, Weishan, Proekt, Irina, Miller, Corey N., Hekim, Can, Jeschke, Jonathan C., Aggarwal, Praful, Broeckel, Ulrich, LaRue, Rebecca S., Henzler, Christine M., Alegre, Maria-Luisa, Anderson, Mark S., August, Avery, Marson, Alexander, Zheng, Ye, Williams, Calvin B., Farrar, Michael A.

“…The developmental programs that generate a broad repertoire of regulatory T cells (T reg cells) able to respond to both self antigens and non-self antigens…”
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Th2 and Th17‐associated immunopathology following SARS‐CoV‐2 breakthrough infection in Spike‐vaccinated ACE2‐humanized mice by Zhang, Tianyi, Magazine, Nicholas, McGee, Michael C., Carossino, Mariano, Veggiani, Gianluca, Kousoulas, Konstantin G., August, Avery, Huang, Weishan

“…Vaccines have demonstrated remarkable effectiveness in protecting against COVID‐19; however, concerns regarding vaccine‐associated enhanced respiratory…”
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Monoclonal antibodies binding to different epitopes of CD20 differentially sensitize DLBCL to different classes of chemotherapy by Lee, Brian, Pierpont, Tim, August, Avery, Richards, Kristy

“…Introduction Rituximab (R), an anti-CD20 monoclonal antibody (mAb) and the world’s first approved antibody for oncology patients, was combined with the CHOP…”
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Author Correction: ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells by Huang, Weishan, Solouki, Sabrina, Koylass, Nicholas, Zheng, Song-Guo, August, Avery

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Cell-autonomous requirement for ACE2 across organs in lethal mouse SARS-CoV-2 infection by Tang, Alan T, Buchholz, David W, Szigety, Katherine M, Imbiakha, Brian, Gao, Siqi, Frankfurter, Maxwell, Wang, Min, Yang, Jisheng, Hewins, Peter, Mericko-Ishizuka, Patricia, Leu, N Adrian, Sterling, Stephanie, Monreal, Isaac A, Sahler, Julie, August, Avery, Zhu, Xuming, Jurado, Kellie A, Xu, Mingang, Morrisey, Edward E, Millar, Sarah E, Aguilar, Hector C, Kahn, Mark L

“…Angiotensin-converting enzyme 2 (ACE2) is the cell-surface receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). While its central role in…”
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Beyond Type 1 Regulatory T Cells: Co-expression of LAG3 and CD49b in IL-10-Producing T Cell Lineages by Huang, Weishan, Solouki, Sabrina, Carter, Chavez, Zheng, Song-Guo, August, Avery

“…Type 1 regulatory CD4 T (Tr1) cells express high levels of the immunosuppressive cytokine IL-10 but not the master transcription factor Foxp3, and can suppress…”
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RNA Virus Population Diversity, an Optimum for Maximal Fitness and Virulence by Korboukh, Victoria K., Lee, Cheri A., Acevedo, Ashley, Vignuzzi, Marco, Xiao, Yinghong, Arnold, Jamie J., Hemperly, Stephen, Graci, Jason D., August, Avery, Andino, Raul, Cameron, Craig E.

“…The ability of an RNA virus to exist as a population of genetically distinct variants permits the virus to overcome events during infections that would…”
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Inhaled corticosteroids as treatment for adolescent asthma: effects on adult anxiety-related outcomes in a murine model by Caulfield, Jasmine I., Ching, Allison M., Cover, Erin M., August, Avery, Craig, Timothy, Kamens, Helen M., Cavigelli, Sonia A.

“…Rationale Allergic asthma, typically controlled with inhaled corticosteroids (ICS), is the leading chronic health condition for youth under 18 years of age…”
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Differential expression of microRNAs in exhaled breath condensates of patients with asthma, patients with chronic obstructive pulmonary disease, and healthy adults by Pinkerton, Mark, BS, Chinchilli, Vernon, PhD, Banta, Erin, MD, Craig, Timothy, DO, August, Avery, PhD, Bascom, Rebecca, MD, Cantorna, Margherita, PhD, Harvill, Eric, PhD, Ishmael, Faoud T., MD, PhD

“…Exhaled breath condensates (EBCs) offer a noninvasive approach to sample the fluid lining the respiratory tract and carries great potential as a source of…”
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Correction to: Inhaled corticosteroids as treatment for adolescent asthma: effects on adult anxiety-related outcomes in a murine model by Caulfield, Jasmine I., Ching, Allison M., Cover, Erin M., August, Avery, Craig, Timothy, Kamens, Helen M., Cavigelli, Sonia A.

“…A Correction to this paper has been published: https://doi.org/10.1007/s00213-021-05778-y…”
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Amino acid starvation sensing dampens IL-1β production by activating riboclustering and autophagy by Battu, Srikanth, Afroz, Sumbul, Giddaluru, Jeevan, Naz, Saima, Huang, Weishan, Khumukcham, Saratchandra Singh, Khan, Rafiq Ahmad, Bhat, Saleem Yousuf, Qureshi, Insaf Ahmed, Manavathi, Bramanandam, Khan, Aleem Ahmed, August, Avery, Hasnain, Seyed Ehtesham, Khan, Nooruddin

“…Activation of the amino acid starvation response (AAR) increases lifespan and acute stress resistance as well as regulates inflammation. However, the…”
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Self-Assembly Protein Nanogels for Safer Cancer Immunotherapy by Purwada, Alberto, Tian, Ye F., Huang, Weishan, Rohrbach, Kathleen M., Deol, Simrita, August, Avery, Singh, Ankur

“…Soluble antigen‐based cancer vaccines have poor retention in tissues along with suboptimal antigen processing by dendritic cells. Multiple booster doses are…”
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Targeting kinase ITK treats autoimmune arthritis via orchestrating T cell differentiation and function by Chen, Ye, Liang, Rongzhen, Shi, Xiaoyi, Shen, Rong, Liu, Liu, Liu, Yan, Xue, Youqiu, Guo, Xinghua, Dang, Junlong, Zeng, Donglan, Huang, Feng, Sun, Jianbo, Zhang, Jingwen, Wang, Julie, Olsen, Nancy, August, Avery, Huang, Weishan, Pan, Yunfeng, Zheng, Song Guo

“…IL-2 inducible T cell kinase (ITK) is critical in T helper subset differentiation and its inhibition has been suggested for the treatment of T cell-mediated…”
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Neuropilin-1 Identifies a New Subpopulation of TGF-β-Induced Foxp3 + Regulatory T Cells With Potent Suppressive Function and Enhanced Stability During Inflammation by Chen, Weiqian, Huang, Weishan, Xue, Youqiu, Chen, Ye, Qian, Wenbin, Ma, Jilin, August, Avery, Wang, Julie, Zheng, Song Guo, Lin, Jin

“…CD4 Foxp3  regulatory T cells (Tregs) play a crucial role in preventing autoimmunity and inflammation. There are naturally-derived in the thymus (tTreg),…”
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Intranasal Vaccination with Recombinant TLR2-Active Outer Membrane Vesicles Containing Sequential M2e Epitopes Protects against Lethal Influenza a Challenge by Kannan, Nisha, Choi, Annette, Rivera De Jesus, Mariela A, Wei, Peter Male, Sahler, Julie Marie, Curley, Stephanie Marie, August, Avery, DeLisa, Matthew P, Whittaker, Gary R, Putnam, David

“…Influenza is a highly contagious respiratory disease, resulting in an estimated 3 to 5 million cases of severe illness annually. While most influenza vaccines…”
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Targeting Interleukin-2-Inducible T-Cell Kinase (ITK) Differentiates GVL and GVHD in Allo-HSCT by Mammadli, Mahinbanu, Huang, Weishan, Harris, Rebecca, Sultana, Aisha, Cheng, Ying, Tong, Wei, Pu, Jeffery, Gentile, Teresa, Dsouza, Shanti, Yang, Qi, Bah, Alaji, August, Avery, Karimi, Mobin

“…Allogeneic hematopoietic stem cell transplantation is a potentially curative procedure for many malignant diseases. Donor T cells prevent disease recurrence…”
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