Search Results - "Auger, L."

Krylov solvers in a vertical‐slice version of the semi‐implicit semi‐Lagrangian AROME model by Burgot, T., Auger, L., Bénard, P.

“…To circumvent the scalability problem due to global communication involved in spectral transforms, a vertical‐slice version of the dynamical core where all…”
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The Autoimmunity-Associated Gene PTPN22 Potentiates Toll-like Receptor-Driven, Type 1 Interferon-Dependent Immunity by Wang, Yaya, Shaked, Iftach, Stanford, Stephanie M., Zhou, Wenbo, Curtsinger, Julie M., Mikulski, Zbigniew, Shaheen, Zachary R., Cheng, Genhong, Sawatzke, Kristy, Campbell, Amanda M., Auger, Jennifer L., Bilgic, Hatice, Shoyama, Fernanda M., Schmeling, David O., Balfour, Henry H., Hasegawa, Kiminori, Chan, Andrew C., Corbett, John A., Binstadt, Bryce A., Mescher, Matthew F., Ley, Klaus, Bottini, Nunzio, Peterson, Erik J.

“…Immune cells sense microbial products through Toll-like receptors (TLR), which trigger host defense responses including type 1 interferons (IFNs) secretion. A…”
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Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis by Zachs, Daniel P., Offutt, Sarah J., Graham, Rachel S., Kim, Yohan, Mueller, Jerel, Auger, Jennifer L., Schuldt, Nathaniel J., Kaiser, Claire R. W., Heiller, Abigail P., Dutta, Raini, Guo, Hongsun, Alford, Jamu K., Binstadt, Bryce A., Lim, Hubert H.

“…Targeted noninvasive control of the nervous system and end-organs may enable safer and more effective treatment of multiple diseases compared to invasive…”
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Genomic dosage effects on heterosis in triploid maize by Yao, Hong, Gray, Anjali Dogra, Auger, Donald L., Birchler, James A.

“…The genetic basis of hybrid vigor or heterosis has been debated for more than a century. A popular hypothesis to explain this phenomenon is that there are…”
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A bivalent compound targeting CCR5 and the mu opioid receptor treats inflammatory arthritis pain in mice without inducing pharmacologic tolerance by Dutta, Raini, Lunzer, Mary M, Auger, Jennifer L, Akgün, Eyup, Portoghese, Philip S, Binstadt, Bryce A

“…Pain accompanies rheumatoid arthritis and other chronic inflammatory conditions and is difficult to manage. Although opioids provide potent analgesia, chronic…”
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Understanding mechanisms of novel gene expression in polyploids by Osborn, Thomas C., Chris Pires, J., Birchler, James A., Auger, Donald L., Jeffery Chen, Z., Lee, Hyeon-Se, Comai, Luca, Madlung, Andreas, Doerge, R.W., Colot, Vincent, Martienssen, Robert A.

“…Polyploidy has long been recognized as a prominent force shaping the evolution of eukaryotes, especially flowering plants. New phenotypes often arise with…”
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Dosage balance in gene regulation: biological implications by Birchler, James A., Riddle, Nicole C., Auger, Donald L., Veitia, Reiner A.

“…Classical studies in genetics involving aneuploidy and ploidy comparisons and sex-determination mechanisms indicated a balance phenomenon such that changes of…”
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Plant‐based enveloped Ara h 2 bioparticles display exceptional hypo‐allergenicity by Castenmiller, C., Stigler, M., Kirpas, M. E., Versteeg, S., Akkerdaas, J. H., Pena‐Castellanos, G., Blokhuis, B. R., Dreskin, S. C., Auger, L., Desgagnés, R., Martel, C., Mirande, L., Morel, B., Roberge, J., Stordeur, V., Tropper, G., Vézina, L. P., Gomord, V., Jong, E. C., Redegeld, F., Shreffler, W. G., Aglas, L., Ree, R.

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Nonadditive gene expression in diploid and triploid hybrids of maize by Auger, D.L, Gray, A.D, Ream, T.S, Kato, A, Coe, E.H. Jr, Birchler, J.A

“…The molecular basis of hybrid vigor (heterosis) has remained unknown despite the importance of this phenomenon in evolution and in practical breeding programs…”
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In Search of the Molecular Basis of Heterosis by Birchler, James A., Auger, Donald L., Riddle, Nicole C.

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Bi-Allelic TCRα or β Recombination Enhances T Cell Development but Is Dispensable for Antigen Responses and Experimental Autoimmune Encephalomyelitis by Schuldt, Nathaniel J, Auger, Jennifer L, Hogquist, Kristin A, Binstadt, Bryce A

“…Dual TCRα-expressing T cells outnumber dual TCRβ-expressing cells by ~10:1. As a result, efforts to understand how dual TCR T cells impact immunity have…”
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A Novel Mechanism Underlying Activity-Dependent Pruning in Postnatal Prefrontal Cortex by Auger, Meagan L

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Dosage-Dependent Gene Regulation in Multicellular Eukaryotes: Implications for Dosage Compensation, Aneuploid Syndromes, and Quantitative Traits by Birchler, James A., Bhadra, Utpal, Bhadra, Manika Pal, Auger, Donald L.

“…Evidence from a variety of data suggests that regulatory mechanisms in multicellular eukaryotes have evolved in such a manner that the stoichiometric…”
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Prefrontal cortical GABAergic and NMDA glutamatergic regulation of delayed responding by Auger, Meagan L., Floresco, Stan B.

“…NMDA glutamatergic and GABAergic transmission have both been implicated in regulating working memory functions mediated by the prefrontal cortex (PFC), and…”
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Amelioration of cognitive impairments induced by GABA hypofunction in the male rat prefrontal cortex by direct and indirect dopamine D 1 agonists SKF-81297 and d-Govadine by Auger, Meagan L, Meccia, Juliet, Phillips, Anthony G, Floresco, Stan B

“…Deficits in prefrontal cortex (PFC) GABAergic neurotransmission are linked to cognitive impairments seen in schizophrenia and other disorders, and…”
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Regulation of sustained attention, false alarm responding and implementation of conditional rules by prefrontal GABA A transmission: comparison with NMDA transmission by Auger, Meagan L, Meccia, Juliet, Floresco, Stan B

“…Both prefrontal cortex (PFC) GABA and NMDA transmission regulate attentional processes, yet how they may differentially regulate signal detection or other…”
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Prefrontal cortical GABA modulation of spatial reference and working memory by Auger, Meagan L, Floresco, Stan B

“…Dysfunction in prefrontal cortex (PFC) GABA transmission has been proposed to contribute to cognitive dysfunction in schizophrenia, yet how this system…”
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Regulation of sustained attention, false alarm responding and implementation of conditional rules by prefrontal GABAA transmission: comparison with NMDA transmission by Auger, Meagan L., Meccia, Juliet, Floresco, Stan B.

“…Rationale Both prefrontal cortex (PFC) GABA A and NMDA transmission regulate attentional processes, yet how they may differentially regulate signal detection…”
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CD47 Promotes Autoimmune Valvular Carditis by Impairing Macrophage Efferocytosis and Enhancing Cytokine Production by Meier, Lee A, Faragher, Jessica L, Osinski, Victoria, Auger, Jennifer L, Voeller, Rochus, Marath, Aubyn, Binstadt, Bryce A

“…Systemic autoantibody-mediated diseases accelerate chronic cardiovascular disease in humans. In the K/B.g7 mouse model of spontaneous autoantibody-mediated…”
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Anti-Inflammatory and Proresolving Effects of the Omega-6 Polyunsaturated Fatty Acid Adrenic Acid by Brouwers, Hilde, Jónasdóttir, Hulda S, Kuipers, Marije E, Kwekkeboom, Joanneke C, Auger, Jennifer L, Gonzalez-Torres, Mayra, López-Vicario, Cristina, Clària, Joan, Freysdottir, Jona, Hardardottir, Ingibjorg, Garrido-Mesa, José, Norling, Lucy V, Perretti, Mauro, Huizinga, Tom W J, Kloppenburg, Margreet, Toes, René E M, Binstadt, Bryce, Giera, Martin, Ioan-Facsinay, Andreea

“…Polyunsaturated fatty acids (PUFAs) and their metabolites are potent regulators of inflammation. Generally, omega ( )-3 PUFAs are considered proresolving…”
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