Search Results - "Auer, C."
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Killers 2.0: NK cell therapies at the forefront of cancer control
Published in The Journal of clinical investigation (03-09-2019)“…Natural killer (NK) cells are innate cytotoxic lymphocytes involved in the surveillance and elimination of cancer. As we have learned more and more about the…”
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Flattening the COVID-19 Curve With Natural Killer Cell Based Immunotherapies
Published in Frontiers in immunology (23-06-2020)“…Natural Killer (NK) cells are innate immune responders critical for viral clearance and immunomodulation. Despite their vital role in viral infection, the…”
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Postoperative Natural Killer Cell Dysfunction: The Prime Suspect in the Case of Metastasis Following Curative Cancer Surgery
Published in International journal of molecular sciences (21-10-2021)“…Surgical resection is the foundation for the curative treatment of solid tumors. However, metastatic recurrence due to the difficulty in eradicating…”
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Managing the Inclusion Process in Collaborative Governance
Published in Journal of public administration research and theory (01-10-2011)“…Facilitators that use a collaborative governance approach are regularly pushed, mandated, or naturally desire to achieve broad inclusion of stakeholders in…”
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5
Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination
Published in Nature communications (11-05-2021)“…By conferring systemic protection and durable benefits, cancer immunotherapies are emerging as long-term solutions for cancer treatment. One such approach that…”
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Visualization and Analysis of Second-Order Tensors: Moving Beyond the Symmetric Positive-Definite Case
Published in Computer graphics forum (01-02-2013)“…Tensors provide a powerful language to describe physical phenomena. Consequently, they have a long tradition in physics and appear in various application…”
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Dysfunctional Natural Killer Cells in the Aftermath of Cancer Surgery
Published in International journal of molecular sciences (17-08-2017)“…The physiological changes that occur immediately following cancer surgeries initiate a chain of events that ultimately result in a short pro-, followed by a…”
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Deep learning-assisted radiomics facilitates multimodal prognostication for personalized treatment strategies in low-grade glioma
Published in Scientific reports (11-06-2023)“…Determining the optimal course of treatment for low grade glioma (LGG) patients is challenging and frequently reliant on subjective judgment and limited…”
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Safety and efficacy of autologous cell vaccines in solid tumors: a systematic review and meta-analysis of randomized control trials
Published in Scientific reports (27-02-2023)“…We conducted a systematic review and meta-analysis of randomized control trials to formally assess the safety and efficacy of autologous whole cell vaccines as…”
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Phosphodiesterase-5 inhibition reduces postoperative metastatic disease by targeting surgery-induced myeloid derived suppressor cell-dependent inhibition of Natural Killer cell cytotoxicity
Published in Oncoimmunology (03-06-2018)“…Cancer surgery while necessary for primary tumor removal, has been shown to induce immune suppression and promote metastases in preclinical models and human…”
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Association between perioperative beta blocker use and cancer survival following surgical resection
Published in European journal of surgical oncology (01-08-2018)“…Recent studies have demonstrated an association between beta-blocker exposure and improved survival in multiple cancer types. We sought to investigate the…”
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Surgical Stress Abrogates Pre-Existing Protective T Cell Mediated Anti-Tumor Immunity Leading to Postoperative Cancer Recurrence
Published in PloS one (19-05-2016)“…Anti-tumor CD8+ T cells are a key determinant for overall survival in patients following surgical resection for solid malignancies. Using a mouse model of…”
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Predictors of a true complete response among disappearing liver metastases from colorectal cancer after chemotherapy
Published in Cancer (15-03-2010)“…BACKGROUND: During chemotherapy, some colorectal liver metastases (LMs) disappear on serial imaging. This disappearance may represent a complete response (CR)…”
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Vanadyl sulfate-enhanced oncolytic virus immunotherapy mediates the antitumor immune response by upregulating the secretion of pro-inflammatory cytokines and chemokines
Published in Frontiers in immunology (28-11-2022)“…Oncolytic viruses (OVs) are promising anticancer treatments that specifically replicate in and kill cancer cells and have profound immunostimulatory…”
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Preventing Surgery-Induced NK Cell Dysfunction Using Anti-TGF-β Immunotherapeutics
Published in International journal of molecular sciences (23-11-2022)“…Natural Killer (NK) cell cytotoxicity and interferon-gamma (IFNγ) production are profoundly suppressed postoperatively. This dysfunction is associated with…”
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Hepatopancreaticobiliary Resection Arginine Immunomodulation (PRIMe) trial: protocol for a randomised phase II trial of the impact of perioperative immunomodulation on immune function following resection for hepatopancreaticobiliary malignancy
Published in BMJ open (05-04-2024)“…IntroductionSurgical stress results in immune dysfunction, predisposing patients to infections in the postoperative period and potentially increasing the risk…”
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Patients’ perceptions on temporomandibular disorder treatment with hydrostatic oral splints - a pilot study
Published in BDJ open (05-02-2022)“…Objective To evaluate temporomandibular disorder (TMD) treatment with a prefabricated, hydrostatic oral splint (HOS) based on self-reported patient’s symptoms…”
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New Anticancer Drugs: Reliably Assessing "Value" While Addressing High Prices
Published in Current oncology (Toronto) (28-04-2024)“…Countries face challenges in paying for new drugs. High prices are driven in part by exploding drug development costs, which, in turn, are driven by essential…”
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Intracranial complications of sinogenic and otogenic infections in children: an ESPN survey on their occurrence in the pre-COVID and post-COVID era
Published in Child's nervous system (01-04-2024)“…Background COVID-19 pandemic is thought to have changed the epidemiology of some pediatric neurosurgical disease: among them are the intracranial complications…”
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Safety and efficacy of autologous tumour cell vaccines as a cancer therapeutic to treat solid tumours and haematological malignancies: a meta-analysis protocol for two systematic reviews
Published in BMJ open (08-06-2020)“…IntroductionAutologous cancer cell vaccines are promising personalised immunotherapeutic options for solid and haematological malignancies that uses the…”
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