Search Results - "Audet, Gerald N"

Cardiovascular and thermoregulatory biomarkers of heat stroke severity in a conscious rat model by Quinn, Carrie M, Duran, Rocio M, Audet, Gerald N, Charkoudian, Nisha, Leon, Lisa R

“…Multiorgan failure is a catastrophic consequence of heat stroke (HS) and considered the underlying etiology of mortality. Identifying novel biomarkers capable…”
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Temporal response of positive and negative regulators in response to acute and chronic exercise training in mice by Olenich, Sara A., Gutierrez‐Reed, Navarre, Audet, Gerald N., Olfert, I. Mark

“…Key points •  Angiogenic regulators respond to acute exercise with different temporal expression patterns (e.g. 2–4 h versus 12–24 h) creating a complex…”
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Effects of detraining on the temporal expression of positive and negative angioregulatory proteins in skeletal muscle of mice by Olenich, Sara A., Audet, Gerald N., Roberts, Kathleen A., Olfert, I. Mark

“…Key points Skeletal muscle capillary regression is associated with elevated thrombospondin‐1 and vascular endothelial growth factor protein expression with…”
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Chronic delivery of a thrombospondin-1 mimetic decreases skeletal muscle capillarity in mice by Audet, Gerald N, Fulks, Daniel, Stricker, Janelle C, Olfert, I Mark

“…Angiogenesis is an essential process for normal skeletal muscle function. There is a growing body of evidence suggesting that thrombospondin-1 (TSP-1), a…”
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Expression of angiogenic regulators and skeletal muscle capillarity in selectively bred high aerobic capacity mice by Audet, Gerald N., Meek, Thomas H., Garland Jr, Theodore, Olfert, I. Mark

“…Selective breeding for high voluntary wheel running in untrained mice has resulted in a ‘mini muscle’ (MM) phenotype, which has increased skeletal muscle…”
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Cardiovascular and thermoregulatory dysregulation over 24 h following acute heat stress in rats by Quinn, Carrie M, Audet, Gerald N, Charkoudian, Nisha, Leon, Lisa R

“…The influences of severe heat stroke (HS) on cardiovascular function during recovery are incompletely understood. We hypothesized that HS would elicit a heart…”
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Altered hypothalamic inflammatory gene expression correlates with heat stroke severity in a conscious rodent model by Audet, Gerald N, Dineen, Shauna M, Quinn, Carrie M, Leon, Lisa R

“…Abstract It has been suggested that heat-induced hypothalamic damage mediates core temperature ( Tc ) disturbances during heat stroke (HS) recovery; this is…”
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Point-of-care cardiac troponin test accurately predicts heat stroke severity in rats by Audet, Gerald N, Quinn, Carrie M, Leon, Lisa R

“…Heat stroke (HS) remains a significant public health concern. Despite the substantial threat posed by HS, there is still no field or clinical test of HS…”
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Pretreatment with indomethacin results in increased heat stroke severity during recovery in a rodent model of heat stroke by Audet, Gerald N, Dineen, Shauna M, Stewart, Delisha A, Plamper, Mark L, Pathmasiri, Wimal W, McRitchie, Susan L, Sumner, Susan J, Leon, Lisa R

“…It has been suggested that medications can increase heat stroke (HS) susceptibility/severity. We investigated whether the nonsteroidal anti-inflammatory drug…”
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Energy Homeostasis Is Disrupted During Recovery From Heat Stroke by Mayer, Thomas A, Leon, Lisa R, Audet, Gerald N

“…Abstract only Heat stroke is a life‐threatening medical condition that affects thousands of Service Members and civilians every year. Loss of function of…”
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Stress and Traumatic Brain Injury Elicit Similar Cytokine Responses in Blood and Liver by Mayer, Thomas A, Audet, Gerald N, Scrimgeour, Angus G

“…Abstract only Mildtraumatic brain injury (mTBI) is a major health issue comprising aheterogeneous and complex array of pathologies. Little is understood about…”
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Prior Infection and Resultant Coagulopathy Increase Heat Stroke Severity by Dineen, Shauna Marie, Plamper, Mark L., Ward, Jermaine A., Audet, Gerald N, Leon, Lisa R

“…Abstract only Anecdotally, it has been suggested that prior viral infection increases heat stroke (HS) susceptibility and severity. HS and systemic infection…”
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Monocyte chemoattractant protein‐1 expression in the lung and kidney is a marker of severity during heat stroke recovery in rats by Plamper, Mark L, Ward, Jermaine A, Leon, Lisa R, Audet, Gerald N

“…Abstract only Heat Stroke (HS) is a common environmental threat to both civilian and war fighter populations. Building on previous studies, our aim is to…”
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Kidney Injury Marker‐1: A Potential Point‐of‐Care Biomarker of Heat Stress by Audet, Gerald N, Ward, Jermaine A, Dineen, Shauna M, Cheuvront, Samuel N, Leon, Lisa R

“…Abstract only Heat injury/stroke (HI/S) is a substantial threat to military operational readiness as well as athletic and occupational performance. There are…”
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Ibuprofen Pre‐Treatment Increases Biomarkers of Heat Stroke Severity and Attenuates Fever during Recovery in Conscious Rats by Audet, Gerald N, Duran, Rocio M, Ward, Jermaine A, Leon, Lisa R

“…Abstract only Heat stroke (HS) is a significant environmental threat to both military and civilian populations. We have shown previously in aconscious rodent…”
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Prior Infection and Prior Heat Illness as Risk Factors for Exertional Heat Stroke by King, Michelle A., Ward, Matthew D., Gabrial, Charles H., Audet, Gerald N., Adams, Bruce, Leon, Lisa R

“…Abstract only Anecdotal evidence suggests that incidence of exertional heat stroke (EHS) is higher in individuals that have experienced prior infection, prior…”
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Muscle‐specific VEGF knockout disrupts thermoregulation without altering mitochondrial morphometry or activity by Mandler, William Kyle, Audet, Gerald N, Olfert, I Mark

“…Abstract only VEGF is believed to enhance thermogenesis in response to cold exposure through promoting angiogenesis, enhancing metabolism, and upregulating…”
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Increased systemic TNFα reduces skeletal muscle capillarity but does not change skeletal muscle fatigability in a mouse model of COPD by Audet, Gerald N, Mandler, W. Kyle, Thapa, Dharendra, Stricker, Janelle C, Zachwieja, Nicole, Olfert, I. Mark

“…Abstract only Increased systemic inflammation is associated with several different pathologies, including chronic obstructive pulmonary disease(COPD). Systemic…”
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The Effect of Physical Deconditioning on Skeletal Muscle Expression of Vascular Endothelial Growth Factor (VEGF): 1750 Board #283 June 1 2:00 PM - 3:30 PM by Roberts, Kathleen A., Audet, Gerald N., Olfert, I. Mark

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Genetics shift the angio‐adaptive balance in skeletal muscle of mice selected for high running capacity by Audet, Gerald N, Meek, Thomas H., Garland, Theodore, Olfert, I Mark

“…Abstract only Selective breeding for voluntary wheel running has resulted in mice with high inherited exercise capacity, which have been termed “mini muscle’…”
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