Search Results - "Auclair, M."
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Signal peptidase I: Cleaving the way to mature proteins
Published in Protein science (01-01-2012)“…Signal peptidase I (SPase I) is critical for the release of translocated preproteins from the membrane as they are transported from a cytoplasmic site of…”
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Characterization of diabetic osteoarthritic cartilage and role of high glucose environment on chondrocyte activation: toward pathophysiological delineation of diabetes mellitus-related osteoarthritis
Published in Osteoarthritis and cartilage (01-09-2015)“…Summary Objective To examine the relationship between osteoarthritis (OA) and type 2 diabetes mellitus (DM). Methods OA cartilage from DM and non-DM patients…”
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Calcium sensitive ring-like oligomers formed by synaptotagmin
Published in Proceedings of the National Academy of Sciences - PNAS (23-09-2014)“…The synaptic vesicle protein synaptotagmin-1 (SYT) is required to couple calcium influx to the membrane fusion machinery. However, the structural mechanism…”
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Measurement of anomalous fading for feldspar IRSL using SAR
Published in Radiation measurements (01-08-2003)“…Age underestimates and wide equivalent paleodose distributions are commonly observed in IRSL dating of feldspar minerals using both multiple and single aliquot…”
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Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence
Published in Cell death and differentiation (01-10-2007)“…Lipodystrophic syndromes associated with mutations in LMNA, encoding A-type lamins, and with HIV antiretroviral treatments share several clinical…”
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Towards a prediction of long-term anomalous fading of feldspar IRSL
Published in Radiation measurements (01-08-2003)“…Anomalous fading of the infrared stimulated luminescence in feldspar is described by a new equation in which the unwanted loss of luminescence is given as a…”
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Screening and characterization of monoclonal antibodies to the surface antigens of Listeria monocytogenes serotype 4b
Published in Journal of applied microbiology (01-05-2009)“…This study aims to develop and characterize monoclonal antibodies (Mabs) with high specificity and affinity for surface antigens of an epidemiologically…”
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The HIV Protease Inhibitor Indinavir Impairs Sterol Regulatory Element-Binding Protein-1 Intranuclear Localization, Inhibits Preadipocyte Differentiation, and Induces Insulin Resistance
Published in Diabetes (New York, N.Y.) (01-06-2001)“…The HIV Protease Inhibitor Indinavir Impairs Sterol Regulatory Element-Binding Protein-1 Intranuclear Localization, Inhibits Preadipocyte Differentiation, and…”
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Quaternary coastal uplift along the Talara Arc (Ecuador, Northern Peru) from new marine terrace data
Published in Marine geology (30-04-2006)“…Marine terrace sequences have been investigated along the Talara Arc, a 1000-km-long stretch of the coast of Ecuador and northern Peru, characterized by…”
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Cartilage in the context of hyperglycemia and diabetes: Further pathophysiological clues for diabetes-related osteoarthritis
Published in Osteoarthritis and cartilage (01-04-2015)Get full text
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A solution to anomalous fading and age shortfalls in optical dating of feldspar minerals
Published in Earth and planetary science letters (15-09-1999)“…Recent reports of age underestimations for events of interest in both palaeoclimatology and archaeology have led to questioning the validity of using…”
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A global approach for solving evolutive heat transfer for image denoising and inpainting
Published in IEEE transactions on image processing (01-09-2006)“…This paper proposes an alternative to partial differential equations (PDEs) for solving problems in computer vision based on evolutive heat transfer…”
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Fenofibrate Improves Liver Function and Reduces the Toxicity of the Bile Acid Pool in Patients With Primary Biliary Cholangitis and Primary Sclerosing Cholangitis Who Are Partial Responders to Ursodiol
Published in Clinical pharmacology and therapeutics (01-12-2020)“…Cholestatic liver diseases result in the hepatic retention of bile acids, causing subsequent liver toxicity. Peroxisome proliferator‐activated receptor alpha…”
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Luminescence dating of a gigantic palaeolandslide in the Gobi-Altay mountains, Mongolia
Published in Quaternary geochronology (2007)“…In an attempt to date a palaeolandslide that took place along the Baga Bogd Massif, in Mongolia, the infrared stimulated luminescence (IRSL) method has been…”
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Plio-Quaternary uplift of the Manta Peninsula and La Plata Island and the subduction of the Carnegie Ridge, central coast of Ecuador
Published in Journal of South American earth sciences (01-11-2006)“…This paper quantifies the uplift of the Manta Peninsula and La Plata Island (Ecuador) using marine terraces. These marine terraces are part of a more extensive…”
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Fenofibrate Downregulates NF-κB Signaling to Inhibit Pro-inflammatory Cytokine Secretion in Human THP-1 Macrophages and During Primary Biliary Cholangitis
Published in Inflammation (01-12-2022)“…Chronic liver diseases, e.g., cholestasis, are negatively impacted by inflammation, which further aggravates liver injury. Pharmacotherapy targeting the…”
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Nanodisc-cell fusion: control of fusion pore nucleation and lifetimes by SNARE protein transmembrane domains
Published in Scientific reports (06-06-2016)“…The initial, nanometer-sized connection between the plasma membrane and a hormone- or neurotransmitter-filled vesicle –the fusion pore– can flicker open and…”
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Reduced dimethyl sulfoxide concentrations successfully cryopreserve human hematopoietic stem cells with multi-lineage long-term engraftment ability in mice
Published in Cytotherapy (Oxford, England) (01-12-2021)“…The cryopreservation of hematopoietic stem cells (HSCs) in dimethyl sulfoxide (DMSO) is used widely, but DMSO toxicity in transplant patients and the effects…”
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Different prelamin A forms accumulate in human fibroblasts: a study in experimental models and progeria
Published in European journal of histochemistry (01-01-2009)“…Lamin A is a component of the nuclear lamina mutated in a group of human inherited disorders known as laminopathies. Among laminopathies, progeroid syndromes…”
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