Search Results - "Auchampach, J A"

Blockade of ATP-Sensitive Potassium Channels Prevents Myocardial Preconditioning in Dogs by Gross, Garrett J, Auchampach, John A

“…Single or multiple brief periods of ischemia (preconditioning) have been shown to protect the myocardium from infarction after a subsequent more prolonged…”
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Blockade of ischaemic preconditioning in dogs by the novel ATP dependent potassium channel antagonist sodium 5-hydroxydecanoate by Auchampach, J A, Grover, G J, Gross, G J

“…The aims were: (1) to determine if a new ischaemia selective ATP dependent potassium (KATP) channel antagonist, sodium 5-hydroxydecanoate (5-HD), blocks…”
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Adenosine receptor subtypes in the heart: therapeutic opportunities and challenges by Auchampach, J A, Bolli, R

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Pharmacological evidence for a role of ATP-dependent potassium channels in myocardial stunning by AUCHAMPACH, J. A, MARUYAMA, M, CAVERO, I, GROSS, G. J

“…Several recent studies suggest that activation of ATP-dependent potassium (K(ATP)) channels in the myocardium plays an important cardioprotective role during…”
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The new K+ channel opener Aprikalim (RP 52891) reduces experimental infarct size in dogs in the absence of hemodynamic changes by Auchampach, J A, Maruyama, M, Cavero, I, Gross, G J

“…The objective of the present study was to determine the effect of a novel K+ channel opener, Aprikalim (RP 52891;…”
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Role of ATP dependent potassium channels in myocardial ischaemia by Gross, G J, Auchampach, J A

“…Recently, a class of potassium (K) channels has been discovered which are regulated by the intracellular level of ATP. These channels have been termed ATP…”
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Cardioprotective effects of monophosphoryl lipid A, a novel endotoxin analogue, in the dog by Yao, Z, Auchampach, J A, Pieper, G M, Gross, G J

“…The major objective of the present study was to determine the effects of a new endotoxin analogue, monophosphoryl lipid A (MLA), on myocardial infarct size in…”
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Anti-ischaemic actions of potassium channel openers in experimental myocardial ischaemia/reperfusion injury in dogs by Auchampach, J A, Gross, G J

“…The effect of three potassium channel openers, nicorandil, aprikalim, and bimakalim, on experimental myocardial ischaemia/reperfusion injury was examined in…”
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Cardioprotective effects of nicorandil by Gross, G J, Auchampach, J A, Maruyama, M, Warltier, D C, Pieper, G M

“…The effects of nicorandil, a nicotinamide nitrate with K(+)-channel-opening activity, was investigated in several models of ischemia-reperfusion injury in…”
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Reduction in myocardial infarct size by the new potassium channel opener bimakalim by Auchampach, J A, Gross, G J

“…We examined the effect of a new potassium channel opener, bimakalim, on myocardial infarct size (IS) in dogs. Barbital-anesthetized dogs were subjected to 90…”
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Cardioprotective actions of potassium channel openers by Auchampach, J A, Maruyama, M, Gross, G J

“…The potential cardioprotective effect of two pure potassium channel openers, bimakalim (EMD 52692) and aprikalim (RP 52891), on myocardial…”
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Effect of the platelet-activating factor antagonist RP 59227 (Tulopafant) on myocardial ischemia/reperfusion injury and neutrophil function by Auchampach, J A, Pieper, G M, Cavero, I, Gross, G J

“…The effect of the platelet activating factor antagonist RP 59227 (Tulopafant) on myocardial infarct size was compared to that of a vehicle-treated control…”
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A(1) or A(3) adenosine receptors induce late preconditioning against infarction in conscious rabbits by different mechanisms by Takano, H, Bolli, R, Black, Jr, R G, Kodani, E, Tang, X L, Yang, Z, Bhattacharya, S, Auchampach, J A

“…We investigated whether activation of A(1) or A(3) adenosine receptors (ARs) induces late preconditioning (PC) against infarction in conscious rabbits using…”
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PKC-dependent activation of p44/p42 MAPKs during myocardial ischemia-reperfusion in conscious rabbits by Ping, P, Zhang, J, Cao, X, Li, R C, Kong, D, Tang, X L, Qiu, Y, Manchikalapudi, S, Auchampach, J A, Black, R G, Bolli, R

“…Using conscious rabbits, we examined the effect of ischemic preconditioning (PC) on p44 and p42 mitogen-activated protein kinases (MAPKs). We found that both…”
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Adenosine A1 receptors, KATP channels, and ischemic preconditioning in dogs by Auchampach, J A, Gross, G J

“…The objective of the present study was to characterize the role of adenosine in myocardial ischemic preconditioning in the canine heart. Preconditioning with 5…”
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PD 81,723, an allosteric enhancer of the A1 adenosine receptor, lowers the threshold for ischemic preconditioning in dogs by MIZUMURA, T, AUCHAMPACH, J. A, LINDEN, J, BRUNS, R. F, GROSS, G. J

“…PD 81,723 (PD) acts allosterically to increase agonist binding to A1 adenosine receptors and to enhance functional A1 receptor-mediated responses in the heart…”
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A(3) adenosine receptor activation attenuates neutrophil function and neutrophil-mediated reperfusion injury by Jordan, J E, Thourani, V H, Auchampach, J A, Robinson, J A, Wang, N P, Vinten-Johansen, J

“…This study tested the hypothesis that A(3) adenosine receptors inhibit neutrophil (PMN) function and PMN-mediated reperfusion injury…”
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Selective activation of A3 adenosine receptors with N6-(3-iodobenzyl)adenosine-5'-N-methyluronamide protects against myocardial stunning and infarction without hemodynamic changes in conscious rabbits by AUCHAMPACH, J. A, RIZVI, A, QIU, Y, TANG, X.-L, MALDONADO, C, TESCHNER, S, BOLLI, R

“…To examine the cardioprotective role of A3 adenosine receptors during myocardial ischemia/reperfusion injury, we tested the effect of…”
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Attenuation of Oxidant-Induced Lung Injury by 21-Aminosteroids (Lazaroids): Correlation with the mRNA Expression for E-Selectin, P-Selectin, ICAM-1, and VCAM-1 by Griffin, Robert L., Krzesicki, Raymond F., Fidler, Stephen F., Rosenbloom, Craig L., Auchampach, John A., Manning, Anthony M., Haas, Joseph V., Cammarata, Sue K., Chin, Jia En, Richards, Ivan M.

“…We compared the effects of treatment with methylprednisolone or the 21-aminosteroids, U-74389 and U-74006F (Tirilizad mesylate), on hyperoxic lung injury and…”
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In vitro activation of brain protein kinase C by the cannabinoids by Hillard, C J, Auchampach, J A

“…The cannabinoids have been shown to affect both membrane lipid ordering and the activities of several membrane-associated proteins. We have investigated the…”
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