Search Results - "Auchère, Francoise"

2-Thioxanthines Are Mechanism-based Inactivators of Myeloperoxidase That Block Oxidative Stress during Inflammation by Tidén, Anna-Karin, Sjögren, Tove, Svensson, Mats, Bernlind, Alexandra, Senthilmohan, Revathy, Auchère, Francoise, Norman, Henrietta, Markgren, Per-Olof, Gustavsson, Susanne, Schmidt, Staffan, Lundquist, Stefan, Forbes, Louisa V., Magon, Nicholas J., Paton, Louise N., Jameson, Guy N.L., Eriksson, Håkan, Kettle, Anthony J.

“…Myeloperoxidase (MPO) is a prime candidate for promoting oxidative stress during inflammation. This abundant enzyme of neutrophils uses hydrogen peroxide to…”
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Dysfunction of mitochondrial Lon protease and identification of oxidized protein in mouse brain following exposure to MPTP: Implications for Parkinson disease by Bulteau, Anne-Laure, Mena, Natalia P., Auchère, Françoise, Lee, Irene, Prigent, Annick, Lobsiger, Christian S., Camadro, Jean-Michel, Hirsch, Etienne C.

“…Compelling evidence suggests that mitochondrial dysfunction leading to reactive oxygen species (ROS) production and protein oxidation could represent a…”
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The adaptive response to alternative carbon sources in the pathogen Candida albicans involves a remodeling of thiol- and glutathione-dependent redox status by Bayot, Juliette, Martin, Caroline, Chevreux, Guillaume, Camadro, Jean-Michel, Auchère, Françoise

“…Candida albicans is an opportunist pathogen responsible for a large spectrum of infections, from superficial mycosis to systemic diseases known as candidiasis…”
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Impaired nuclear Nrf2 translocation undermines the oxidative stress response in Friedreich ataxia by Paupe, Vincent, Dassa, Emmanuel P, Goncalves, Sergio, Auchère, Françoise, Lönn, Maria, Holmgren, Arne, Rustin, Pierre

“…Friedreich ataxia originates from a decrease in mitochondrial frataxin, which causes the death of a subset of neurons. The biochemical hallmarks of the disease…”
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Potent Reversible Inhibition of Myeloperoxidase by Aromatic Hydroxamates by Forbes, Louisa V., Sjögren, Tove, Auchère, Françoise, Jenkins, David W., Thong, Bob, Laughton, David, Hemsley, Paul, Pairaudeau, Garry, Turner, Rufus, Eriksson, Håkan, Unitt, John F., Kettle, Anthony J.

“…The neutrophil enzyme myeloperoxidase (MPO) promotes oxidative stress in numerous inflammatory pathologies by producing hypohalous acids. Its inadvertent…”
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The adaptive response to iron involves changes in energetic strategies in the pathogen Candida albicans by Duval, Celia, Macabiou, Carole, Garcia, Camille, Lesuisse, Emmanuel, Camadro, Jean‐Michel, Auchère, Françoise

“…Candida albicans is an opportunist pathogen responsible for a large spectrum of infections, from superficial mycosis to systemic diseases known as candidiasis…”
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Tissue- and cell-specific mitochondrial defect in Parkin-deficient mice by Damiano, Maria, Gautier, Clément A, Bulteau, Anne-Laure, Ferrando-Miguel, Rosa, Gouarne, Caroline, Paoli, Marc Giraudon, Pruss, Rebecca, Auchère, Françoise, L'Hermitte-Stead, Caroline, Bouillaud, Frédéric, Brice, Alexis, Corti, Olga, Lombès, Anne

“…Loss of Parkin, encoded by PARK2 gene, is a major cause of autosomal recessive Parkinson's disease. In Drosophila and mammalian cell models Parkin has been…”
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Modulation of the specific glutathionylation of mitochondrial proteins in the yeast Saccharomyces cerevisiae under basal and stress conditions by Gergondey, Rachel, Garcia, Camille, Marchand, Christophe H, Lemaire, Stephane D, Camadro, Jean-Michel, Auchère, Françoise

“…The potential biological consequences of oxidative stress and changes in glutathione levels include the oxidation of susceptible protein thiols and reversible…”
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Gex1 is a yeast glutathione exchanger that interferes with pH and redox homeostasis by Dhaoui, Manel, Auchère, Françoise, Blaiseau, Pierre-Louis, Lesuisse, Emmanuel, Landoulsi, Ahmed, Camadro, Jean-Michel, Haguenauer-Tsapis, Rosine, Belgareh-Touzé, Naïma

“…In the yeast Saccharomyces cerevisiae, glutathione plays a major role in heavy metal detoxification and protection of cells against oxidative stress. We show…”
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Glutathione-dependent redox status of frataxin-deficient cells in a yeast model of Friedreich's ataxia by Auchère, Françoise, Santos, Renata, Planamente, Sara, Lesuisse, Emmanuel, Camadro, Jean-Michel

“…Friedreich′s ataxia is a neurodegenerative disease caused by reduced expression of the mitochondrial protein frataxin. The main phenotypic features of…”
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The yeast metacaspase is implicated in oxidative stress response in frataxin-deficient cells by Lefevre, Sophie, Sliwa, Dominika, Auchère, Françoise, Brossas, Caroline, Ruckenstuhl, Christoph, Boggetto, Nicole, Lesuisse, Emmanuel, Madeo, Frank, Camadro, Jean-Michel, Santos, Renata

“…► Sensitivity of yeast frataxin-deficient cells to hydrogen peroxide is partially mediated by metacaspase. ► In the absence of metacaspase, frataxin-deficient…”
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Overexpression of the yeast frataxin homolog (Yfh1): contrasting effects on iron-sulfur cluster assembly, heme synthesis and resistance to oxidative stress by Seguin, Alexandra, Bayot, Aurélien, Dancis, Andrew, Rogowska-Wrzesinska, Adelina, Auchère, Françoise, Camadro, Jean-Michel, Bulteau, Anne-Laure, Lesuisse, Emmanuel

“…Friedreich's ataxia is generally associated with defects in [Fe-S] cluster assembly/stability and heme synthesis and strong susceptibility to oxidative stress…”
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What is the ultimate fate of superoxide anion in vivo? by Auchère, Françoise, Rusnak, Frank

“…For three decades, oxidative stress and the role of reactive oxygen species in biology have been extensively studied. Recently, a new interest in these areas…”
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Comparative electrochemical study of superoxide reductases by Cordas, Cristina M., Raleiras, Patrícia, Auchère, Françoise, Moura, Isabel, Moura, José J. G.

“…Superoxide reductases are involved in relevant biological electron transfer reactions related to protection against oxidative stress caused by reactive oxygen…”
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The first crystal structure of class III superoxide reductase from Treponema pallidum by Santos-Silva, Teresa, Trincão, José, Carvalho, Ana Luísa, Bonifácio, Cecília, Auchère, Françoise, Raleiras, Patrícia, Moura, Isabel, Moura, José J G, Romão, Maria João

“…Superoxide reductase (SOR) is a metalloprotein containing a non-heme iron centre, responsible for the scavenging of superoxide radicals in the cell. The…”
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Oxidation of Cu, Zn-superoxide dismutase by the myeloperoxidase/hydrogen peroxide/chloride system: functional and structural effects by Auchère, Françoise, Capeillère-Blandin, Chantal

“…This study investigated the functional and structural effects of bovine Cu, Zn-superoxide dismutase (Cu, Zn-SOD) oxidation by the myeloperoxidase…”
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Apn1 AP-endonuclease is essential for the repair of oxidatively damaged DNA bases in yeast frataxin-deficient cells by LEFEVRE, Sophie, BROSSAS, Caroline, AUCHERE, Françoise, BOGGETTO, Nicole, CAMADRO, Jean-Michel, SANTOS, Renata

“…Frataxin deficiency results in mitochondrial dysfunction and oxidative stress and it is the cause of the hereditary neurodegenerative disease Friedreich ataxia…”
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Changes in glutathione-dependent redox status and mitochondrial energetic strategies are part of the adaptive response during the filamentation process in Candida albicans by Hala, Guedouari, Rachel, Gergondey, Arthur, Bourdais, Océane, Vanparis, Anne-Laure, Bulteau, Jean-Michel, Camadro, Françoise, Auchère

“…Candia albicans is an opportunist pathogen responsible for a large spectrum of infections, from superficial mycosis to systemic diseases called candidiasis…”
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P4 - Changes in glutathione-dependent redox status and mitochondrial energetic strategies are part of the adaptive response during the filamentation process in Candida albicans by Hala, Guedouari, Rachel, Gergondey, Arthur, Bourdais, Océane, Vanparis, Anne-Laure, Bulteau, Jean-Michel, Camadro, Françoise, Auchère

“…Candia albicans is an opportunist pathogen responsible for a large spectrum of infections, from superficial mycosis to systemic diseases called candidiasis…”
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Superoxide reductase from the syphilis spirochete Treponema pallidum: crystallization and structure determination using soft X-rays by Santos-Silva, Teresa, Trincão, José, Carvalho, Ana L., Bonifácio, Cecília, Auchère, Françoise, Moura, Isabel, Moura, José J. G., Romão, Maria J.

“…Superoxide reductase is a 14 kDa metalloprotein containing a catalytic non‐haem iron centre [Fe(His)4Cys]. It is involved in defence mechanisms against oxygen…”
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