Search Results - "Aubry, François"
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Manipulation of Subcortical and Deep Cortical Activity in the Primate Brain Using Transcranial Focused Ultrasound Stimulation
Published in Neuron (Cambridge, Mass.) (20-03-2019)“…The causal role of an area within a neural network can be determined by interfering with its activity and measuring the impact. Many current reversible…”
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2
Low-Intensity Focused Ultrasound Modulates Monkey Visuomotor Behavior
Published in Current biology (02-12-2013)“…In vivo feasibility of using low-intensity focused ultrasound (FUS) to transiently modulate the function of regional brain tissue has been recently tested in…”
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3D-printed adaptive acoustic lens as a disruptive technology for transcranial ultrasound therapy using single-element transducers
Published in Physics in medicine & biology (16-01-2018)“…The development of multi-element arrays for better control of the shape of ultrasonic beams has opened the way for focusing through highly aberrating media,…”
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Potential impact of thermal effects during ultrasonic neurostimulation: retrospective numerical estimation of temperature elevation in seven rodent setups
Published in Physics in medicine & biology (09-01-2018)“…In the past decade, a handful but growing number of groups have reported worldwide successful low intensity focused ultrasound induced neurostimulation trials…”
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5
MRI monitoring of temperature and displacement for transcranial focus ultrasound applications
Published in NeuroImage (Orlando, Fla.) (01-01-2020)“…Transcranial focus ultrasound applications applied under MRI-guidance benefit from unrivaled monitoring capabilities, allowing the recording of real-time…”
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6
Offline impact of transcranial focused ultrasound on cortical activation in primates
Published in eLife (12-02-2019)“…To understand brain circuits it is necessary both to record and manipulate their activity. Transcranial ultrasound stimulation (TUS) is a promising…”
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Steering Capabilities of an Acoustic Lens for Transcranial Therapy: Numerical and Experimental Studies
Published in IEEE transactions on biomedical engineering (01-01-2020)“…For successful brain therapy, transcranial focused ultrasound must compensate for the time shifts induced locally by the skull. The patient-specific phase…”
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Real‐time monitoring of tissue displacement and temperature changes during MR‐guided high intensity focused ultrasound
Published in Magnetic resonance in medicine (01-11-2017)“…Purpose The therapy endpoint most commonly used in MR‐guided high intensity focused ultrasound is the thermal dose. Although namely correlated with nonviable…”
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A Basal Forebrain-Cingulate Circuit in Macaques Decides It Is Time to Act
Published in Neuron (Cambridge, Mass.) (22-01-2020)“…The medial frontal cortex has been linked to voluntary action, but an explanation of why decisions to act emerge at particular points in time has been lacking…”
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10
Non-invasive ultrasonic modulation of visual evoked response by GABA delivery through the blood brain barrier
Published in Journal of controlled release (01-02-2020)“…GABA is an inhibitory neurotransmitter that is maintained outside the brain by the blood brain barrier in normal condition. In this paper we demonstrate the…”
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11
Combining brain perturbation and neuroimaging in non-human primates
Published in NeuroImage (Orlando, Fla.) (15-07-2021)“…•Combined brain perturbation and neuroimaging can reveal causal brain mechanisms.•Overview of perturbation methods used with non-human primate…”
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Neuronavigated Repetitive Transcranial Ultrasound Stimulation Induces Long-Lasting and Reversible Effects on Oculomotor Performance in Non-human Primates
Published in Frontiers in physiology (19-08-2020)“…Since the late 2010s, Transcranial Ultrasound Stimulation (TUS) has been used experimentally to carryout safe, non-invasive stimulation of the brain with…”
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Ultrashort echo‐time MRI versus CT for skull aberration correction in MR‐guided transcranial focused ultrasound: In vitro comparison on human calvaria
Published in Medical physics (Lancaster) (01-05-2015)“…Purpose: Transcranial magnetic resonance‐guided focused ultrasound (TcMRgFUS) brain treatment systems compensate for skull‐induced beam aberrations by…”
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14
Transcranial ultrasonic stimulation modulates single-neuron discharge in macaques performing an antisaccade task
Published in Brain stimulation (01-11-2017)“…Low intensity transcranial ultrasonic stimulation (TUS) has been demonstrated to non-invasively and transiently stimulate the nervous system. Although US…”
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15
The macaque anterior cingulate cortex translates counterfactual choice value into actual behavioral change
Published in Nature neuroscience (01-05-2019)“…The neural mechanisms mediating sensory-guided decision-making have received considerable attention, but animals often pursue behaviors for which there is…”
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ITRUSST consensus on standardised reporting for transcranial ultrasound stimulation
Published in Brain stimulation (01-05-2024)“…As transcranial ultrasound stimulation (TUS) advances as a precise, non-invasive neuromodulatory method, there is a need for consistent reporting standards to…”
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MR-Guided Transcranial Focused Ultrasound
Published in Advances in experimental medicine and biology (2016)“…Previous chapters introduced the ability of using focused ultrasound to ablate tissues. It has led to various clinical applications in the treatment of uterine…”
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Combined passive detection and ultrafast active imaging of cavitation events induced by short pulses of high-intensity ultrasound
Published in IEEE transactions on ultrasonics, ferroelectrics, and frequency control (01-03-2011)“…The activation of natural gas nuclei to induce larger bubbles is possible using short ultrasonic excitations of high amplitude, and is required for ultrasound…”
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Simulation of Intracranial Acoustic Fields in Clinical Trials of Sonothrombolysis
Published in Ultrasound in medicine & biology (01-07-2009)“…Abstract Two clinical trials have used ultrasound to improve tPA thrombolysis in patients with acute ischemic stroke. The Combined Lysis of Thrombus in Brain…”
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Efficacy and safety assessment of an ultrasound-based thermal treatment of varicose veins in a sheep model
Published in International journal of hyperthermia (01-01-2020)“…Varicose veins are a common pathology that can be treated by endovenous thermal procedures like radiofrequency ablation (RFA). Such catheter-based techniques…”
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