Search Results - "Aubouy, Agnes"
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Monocytes, particularly nonclassical ones, lose their opsonic and nonopsonic phagocytosis capacity during pediatric cerebral malaria
Published in Frontiers in immunology (21-05-2024)“…Innate immunity is crucial to reducing parasite burden and contributing to survival in severe malaria. Monocytes are key actors in the innate response and,…”
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Kinetics of monocyte subpopulations during experimental cerebral malaria and its resolution in a model of late chloroquine treatment
Published in Frontiers in cellular and infection microbiology (14-10-2022)“…Cerebral malaria (CM) is one of the most severe forms of malaria and is a neuropathology that can lead to death. Monocytes have been shown to accumulate in the…”
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3
Antibacterial, antifungal and antileishmanial activities of indolone-N-oxide derivatives
Published in Journal of antibiotics (01-10-2012)“…An alarming increase in microbial resistance to traditional drugs and classical pharmacophores has spurred the search for new antimicrobial compounds…”
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4
Differential immunomodulatory effects of six pesticides of different chemical classes on human monocyte-derived macrophage functions
Published in Food and chemical toxicology (01-05-2022)“…Exposure to pesticides through eyes, skin, ingestion and inhalation may affects human health by interfering with immune cells, such as macrophages. We…”
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Divergent Roles for Macrophage C-type Lectin Receptors, Dectin-1 and Mannose Receptors, in the Intestinal Inflammatory Response
Published in Cell reports (Cambridge) (31-03-2020)“…Colonic macrophages are considered to be major effectors of inflammatory bowel diseases (IBDs) and the control of gut inflammation through C-type lectin…”
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In vivo validation of anti-malarial activity of crude extracts of Terminalia macroptera, a Malian medicinal plant
Published in Malaria journal (05-02-2018)“…Plasmodium falciparum malaria is still one of the most deadly pathology worldwide. Efficient treatment is jeopardized by parasite resistance to artemisinin and…”
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7
Voltammetric techniques for low-cost on-site routine analysis of thymol in the medicinal plant Ocimum gratissimum
Published in Talanta (Oxford) (01-03-2024)“…The composition of essential oils varies according to culture conditions and climate, which induces a need for simple and inexpensive characterization methods…”
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Short report: lack of prediction of amodiaquine efficacy in treating Plasmodium falciparum malaria by in vitro tests
Published in The American journal of tropical medicine and hygiene (01-09-2004)“…Amodiaquine (AQ) is currently a major candidate for new antimalarial combinations, although in vivo and in vitro tests have been rarely simultaneously…”
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Terminalia albida treatment improves survival in experimental cerebral malaria through reactive oxygen species scavenging and anti-inflammatory properties
Published in Malaria journal (18-12-2019)“…The development of Plasmodium resistance to the last effective anti-malarial drugs necessitates the urgent development of new anti-malarial therapeutic…”
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Forest Fevers: traditional treatment of malaria in the southern lowlands of Laos
Published in Journal of ethnopharmacology (01-03-2020)“…Malaria is still a highly challenging public health issue in southern Lao PDR, with increasing cases of artemisinin resistance and Plasmodium vivax infections…”
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Changes in monocyte subsets are associated with clinical outcomes in severe malarial anaemia and cerebral malaria
Published in Scientific reports (26-11-2019)“…Monocytes are plastic heterogeneous immune cells involved in host-parasite interactions critical for malaria pathogenesis. Human monocytes have been subdivided…”
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12
Antimalarial Properties of Dunnione Derivatives as NQO2 Substrates
Published in Molecules (Basel, Switzerland) (15-10-2019)“…Dunnione, a natural product isolated from the leaves of (Gesneriaceae), acts as a substrate for quinone-reductases that may be associated with its antimalarial…”
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Comparative study of the effects of ziram and disulfiram on human monocyte-derived macrophage functions and polarization: involvement of zinc
Published in Cell biology and toxicology (01-06-2021)“…Ziram, a zinc dithiocarbamate is widely used worldwide as a fungicide in agriculture. In order to investigate ziram-induced changes in macrophage functions and…”
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14
Nrf2, a PPARγ alternative pathway to promote CD36 expression on inflammatory macrophages: implication for malaria
Published in PLoS pathogens (01-09-2011)“…CD36 is the major receptor mediating nonopsonic phagocytosis of Plasmodium falciparum-parasitized erythrocytes by macrophages. Its expression on macrophages is…”
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15
PassStat, a simple but fast, precise and versatile open source potentiostat
Published in HardwareX (01-04-2022)“…[Display omitted] This work presents 4 open source potentiostat solutions for performing accurate measurements in cyclic voltammetry and square wave…”
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From genomic to LC-MS/MS evidence: Analysis of PfEMP1 in Benin malaria cases
Published in PloS one (28-06-2019)“…PfEMP1 is the major protein from parasitic origin involved in the pathophysiology of severe malaria, and PfEMP1 domain subtypes are associated with the…”
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Differences in gene transcriptomic pattern of Plasmodium falciparum in children with cerebral malaria and asymptomatic carriers
Published in PloS one (05-12-2014)“…The mechanisms underlying the heterogeneity of clinical malaria remain largely unknown. We hypothesized that differential gene expression contributes to…”
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Promotion of malaria home-based treatment in Africa: the dangers of creating a second health system
Published in International health (01-12-2011)“…Abstract Many African countries have begun to scale-up home-based management of malaria (HMM) with artemisinin-based combination therapy. Evidence shows that…”
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Plasmodium falciparum Polymorphisms Associated with Ex Vivo Drug Susceptibility and Clinical Effectiveness of Artemisinin-Based Combination Therapies in Benin
Published in Antimicrobial Agents and Chemotherapy (01-01-2014)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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20
Elevated plasma interleukin-8 as a risk factor for mortality in children presenting with cerebral malaria
Published in Infectious diseases of poverty (09-02-2023)“…Cerebral malaria (CM) is a neuropathology which remains one of the deadliest forms of malaria among African children. The kinetics of the pathophysiological…”
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