Search Results - "AuCoin, David P."
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Evaluation of antigen-detecting and antibody-detecting diagnostic test combinations for diagnosing melioidosis
Published in PLoS neglected tropical diseases (01-11-2021)“…Melioidosis, an infectious disease caused by Burkholderia pseudomallei, is endemic in many tropical developing countries and has a high mortality. Here we…”
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Performance evaluation of Active Melioidosis Detect-Lateral Flow Assay (AMD-LFA) for diagnosis of melioidosis in endemic settings with limited resources
Published in PloS one (26-03-2018)“…Melioidosis is a fatal infection caused by the soil saprophyte Burkholderia pseudomallei. Early diagnosis and befitting medical management can significantly…”
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Development of a dual antigen lateral flow immunoassay for detecting Yersinia pestis
Published in PLoS neglected tropical diseases (23-03-2022)“…Yersinia pestis is the causative agent of plague, a zoonosis associated with small mammals. Plague is a severe disease, especially in the pneumonic and…”
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Serum antibody levels to SARS-CoV-2 receptor-binding domain (RBD) in convalescent patients and vaccinated individuals of northern Nevada
Published in PloS one (02-11-2023)“…Antibodies reactive with the SARS-CoV-2 receptor-binding domain (RBD) of the spike protein are associated with viral neutralization, however low antibody…”
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Human Cytomegalovirus Exploits ESCRT Machinery in the Process of Virion Maturation
Published in Journal of Virology (15-10-2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A naturally derived outer-membrane vesicle vaccine protects against lethal pulmonary Burkholderia pseudomallei infection
Published in Vaccine (26-10-2011)“…Highlights ► Outer membrane vesicle (OMV) immunization protects against Burkholderia pseudomallei . ► OMVs contain protein, LPS, and CPS which may contribute…”
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Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens
Published in Nature communications (24-07-2017)“…Burkholderia pseudomallei ( Bp ) and Burkholderia mallei ( Bm ), the etiologic agents of melioidosis and glanders, respectively, cause severe disease in both…”
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Development of a prototype lateral flow immunoassay (LFI) for the rapid diagnosis of melioidosis
Published in PLoS neglected tropical diseases (01-03-2014)“…Burkholderia pseudomallei is a soil-dwelling bacterium and the causative agent of melioidosis. Isolation of B. pseudomallei from clinical samples is the "gold…”
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Development of an antigen detection assay for early point-of-care diagnosis of Zaire ebolavirus
Published in PLoS neglected tropical diseases (01-11-2020)“…The 2013-2016 Ebola virus (EBOV) outbreak in West Africa and the ongoing cases in the Democratic Republic of the Congo have spurred development of a number of…”
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Functional assays to screen and select monoclonal antibodies that target Yersinia pestis
Published in Human vaccines & immunotherapeutics (01-08-2023)“…Yersinia pestis is a gram-negative bacterium that causes plague in animals and humans. Depending on the route of disease transmission, the bacterium can cause…”
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Comparison of a Prototype SARS-CoV-2 Lateral Flow IMMUNOASSAY with the BinaxNOWTM COVID-19 Antigen CARD
Published in Viruses (23-11-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus responsible for the COVID-19 pandemic. From the onset of the pandemic, rapid antigen…”
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In vivo Distribution and Clearance of Purified Capsular Polysaccharide from Burkholderia pseudomallei in a Murine Model
Published in PLoS neglected tropical diseases (12-12-2016)“…Burkholderia pseudomallei is the causative agent of melioidosis, a severe infection prominent in northern Australia and Southeast Asia. The "gold standard" for…”
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Immunoglobulin G subclass switching impacts sensitivity of an immunoassay targeting Francisella tularensis lipopolysaccharide
Published in PloS one (09-04-2018)“…The CDC Tier 1 select agent Francisella tularensis is a small, Gram-negative bacterium and the causative agent of tularemia, a potentially life-threatening…”
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Detection and Quantification of the Capsular Polysaccharide of Burkholderia pseudomallei in Serum and Urine Samples from Melioidosis Patients
Published in Microbiology spectrum (31-08-2022)“…Burkholderia pseudomallei is the causative agent of melioidosis, a life-threatening disease common in Southeast Asia and northern Australia. Melioidosis often…”
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Genome-scale analysis of the genes that contribute to Burkholderia pseudomallei biofilm formation identifies a crucial exopolysaccharide biosynthesis gene cluster
Published in PLoS neglected tropical diseases (28-06-2017)“…Burkholderia pseudomallei, the causative agent of melioidosis, is an important public health threat due to limited therapeutic options for treatment. Efforts…”
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Polysaccharide specific monoclonal antibodies provide passive protection against intranasal challenge with Burkholderia pseudomallei
Published in PloS one (17-04-2012)“…Burkholderia pseudomallei is a Gram-negative bacillus that is the causative agent of melioidosis. The bacterium is inherently resistant to many antibiotics and…”
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IgG subclass and heavy chain domains contribute to binding and protection by mAbs to the poly γ-D-glutamic acid capsular antigen of Bacillus anthracis
Published in PLoS pathogens (01-04-2013)“…Bacterial capsules are common targets for antibody-mediated immunity. The capsule of Bacillus anthracis is unusual among capsules because it is composed of a…”
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Characterization of a Centrifugal Microfluidic Orthogonal Flow Platform
Published in Micromachines (Basel) (20-03-2022)“…To bring to bear the power of centrifugal microfluidics on vertical flow immunoassays, control of flow orthogonally through nanoporous membranes is essential…”
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Betaherpesvirus-Conserved Cytomegalovirus Tegument Protein ppUL32 (pp150) Controls Cytoplasmic Events during Virion Maturation
Published in Journal of Virology (01-08-2006)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Multi-platform Approach for Microbial Biomarker Identification Using Borrelia burgdorferi as a Model
Published in Frontiers in cellular and infection microbiology (11-06-2019)“…The identification of microbial biomarkers is critical for the diagnosis of a disease early during infection. However, the identification of reliable…”
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