Search Results - "Atwood, Daniel"

A study of sirolimus and mTOR kinase inhibitor in a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease by Holditch, Sara J, Brown, Carolyn N, Atwood, Daniel J, Lombardi, Andrew M, Nguyen, Khoa N, Toll, Harrison W, Hopp, Katharina, Edelstein, Charles L

“…Autosomal dominant polycystic kidney disease (PKD) is characterized by cyst formation and growth, which are partially driven by abnormal proliferation of…”
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Expectations versus reality: Understanding the accuracy of impressions made during virtual interviews of pediatric pulmonary fellowship programs by Atwood, Daniel T., Chiel, Laura E., Nelson, Benjamin A., Casey, Alicia M.

“…Rationale As a result of the SARS‐CoV‐2 pandemic, all pediatric pulmonary fellowship programs conducted virtual interviews for the first time in the Fall of…”
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Identification of Irpex and Rhodotorula on surveillance bronchoscopy in a pediatric lung transplant recipient: A case report and review of literature of these atypical fungal organisms by Atwood, Daniel T., Köhler, Julia R., Vargas, Sara O., Wong, Wai, Klouda, Timothy

“…Background Invasive fungal disease (IFD) is a frequent complication in pediatric lung transplant recipients, occurring in up to 12% of patients in the first…”
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Increased mTOR and suppressed autophagic flux in the heart of a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease by Atwood, Daniel J., Pokhrel, Deepak, Brown, Carolyn N., Holditch, Sara J., Bachu, Dheevena M., Thorburn, Andrew, Hopp, Katharina, Edelstein, Charles L.

“…Cardiac hypertrophy is common in autosomal dominant polycystic kidney disease (ADPKD) patients. We found increased heart weight in Pkd1RC/RC and Pkd2WS25/+…”
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The effect of trehalose on autophagy-related proteins and cyst growth in a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease by Atwood, Daniel J., Brown, Carolyn N., Holditch, Sara J., Pokhrel, Deepak, Thorburn, Andrew, Hopp, Katharina, Edelstein, Charles L.

“…Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited disorder characterized by kidney cyst growth often resulting in end-stage renal…”
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The consequences of increased 4E-BP1 in polycystic kidney disease by Holditch, Sara J, Brown, Carolyn N, Atwood, Daniel J, Pokhrel, Deepak, Brown, Sara E, Lombardi, Andrew M, Nguyen, Khoa N, Hill, Ryan C, Lanaspa, Miguel, Hopp, Katharina, Weiser-Evans, Mary C M, Edelstein, Charles L

“…Abstract Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disease, characterized by cyst formation and growth…”
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The effect of MEK1/2 inhibitors on cisplatin-induced acute kidney injury (AKI) and cancer growth in mice by Brown, Carolyn N., Atwood, Daniel J., Pokhrel, Deepak, Ravichandran, Kameswaran, Holditch, Sara J., Saxena, Sanskriti, Miyazaki, Makoto, Nemenoff, Raphael, Weiser-Evans, Mary C.M., Ljubanovic, Danica Galesic, Joy, Melanie S., Edelstein, Charles L.

“…In a clinically-relevant model of 4 week, low-dose cisplatin-induced AKI, mice were injected subcutaneously with non small cell lung cancer (NSCLC) cells that…”
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Metformin does not slow cyst growth in the PCK rat model of polycystic kidney disease by Oto, Ozgur A., Atwood, Daniel J., Chaudhary, Anjana, He, Zhibin, Li, Amy S., Wempe, Michael F., Edelstein, Charles L.

“…Metformin (MET) has the potential to activate p‐AMPK and block mTORC1‐induced proliferation of tubular cells in PKD kidneys. The aim of this study was to…”
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Surgical procedures suppress autophagic flux in the kidney by Brown, Carolyn N., Atwood, Daniel, Pokhrel, Deepak, Holditch, Sara J., Altmann, Christopher, Skrypnyk, Nataliya I., Bourne, Jennifer, Klawitter, Jelena, Blaine, Judith, Faubel, Sarah, Thorburn, Andrew, Edelstein, Charles L.

“…Many surgical models are used to study kidney and other diseases in mice, yet the effects of the surgical procedure itself on the kidney and other tissues have…”
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Mitochondrial and performance adaptations to exercise training in mice lacking skeletal muscle LKB1 by Tanner, Colby B, Madsen, Steven R, Hallowell, David M, Goring, Darren M J, Moore, Timothy M, Hardman, Shalene E, Heninger, Megan R, Atwood, Daniel R, Thomson, David M

“…LKB1 and its downstream targets of the AMP-activated protein kinase family are important regulators of many aspects of skeletal muscle cell function, including…”
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Suppressed Autophagy Drives Increased Cellular Metabolic Activity in Human ADPKD Cells: PO1231 by Atwood, Daniel, Pokhrel, Deepak, Edelstein, Charles L.

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Metformin Worsens Kidney Function and Has No Effect on Cyst Growth in the PCK Rat Model of Autosomal Recessive Polycystic Kidney Disease (ARPKD): FR-PO280 by Oto, Ozgur A., Atwood, Daniel, Chaudhary, Anjana, Edelstein, Charles L.

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Cardiac Hypertrophy in Rodents With Polycystic Kidney Disease (PKD) Before the Onset of Hypertension: FR-PO279 by Oto, Ozgur A., Atwood, Daniel, Chaudhary, Anjana, Edelstein, Charles L.

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Raising Serum Uric Acid With a Uricase Inhibitor Worsens Polycystic Kidney Disease in Rat and Mouse Models: FR-PO249 by Atwood, Daniel, Oto, Ozgur A., Chaudhary, Anjana, Edelstein, Charles L.

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Turning the Kidney Into a Lymphoid Organ: FR-PO250 by Atwood, Daniel, Oto, Ozgur A., Chaudhary, Anjana, Edelstein, Charles L.

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Early treatment with 2-deoxy-d-glucose reduces proliferative proteins in the kidney and slows cyst growth in a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease (PKD) by Atwood, Daniel, He, Zhibin, Miyazaki, Makoto, Hailu, Frehiwet, Klawitter, Jelena, Edelstein, Charles L.

“…In autosomal dominant polycystic kidney disease (ADPKD) there is cyst growth in the kidneys that leads to chronic kidney disease often requiring dialysis or…”
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The Effect of Lowering Uric Acid with a Xanthine Oxidase Inhibitor on PKD in Mice: TH-PO408 by Chaudhary, Anjana, He, Zhibin, Atwood, Daniel, Davidoff, Allen, Edelstein, Charles L.

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Manipulation of Autophagy in PKD Mice: FR-PO566 by Atwood, Daniel, Chaudhary, Anjana, He, Zhibin, Oto, Ozgur A., Edelstein, Charles L.

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Suppressed Autophagic Flux in the Heart in a Hypomorphic Pkd1 Mouse Model of ADPKD: PO1549 by Atwood, Daniel, Brown, Carolyn N., Hopp, Katharina, Edelstein, Charles L.

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Autophagy Inhibition Ameliorates Polycystic Kidney Disease: PO1214 by Atwood, Daniel, Pokhrel, Deepak, Dwivedi, Nidhi, Hopp, Katharina, Edelstein, Charles L.

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