Search Results - "Attia, Steven"

Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial by Tawbi, Hussein A, Burgess, Melissa, Bolejack, Vanessa, Van Tine, Brian A, Schuetze, Scott M, Hu, James, D'Angelo, Sandra, Attia, Steven, Riedel, Richard F, Priebat, Dennis A, Movva, Sujana, Davis, Lara E, Okuno, Scott H, Reed, Damon R, Crowley, John, Butterfield, Lisa H, Salazar, Ruth, Rodriguez-Canales, Jaime, Lazar, Alexander J, Wistuba, Ignacio I, Baker, Laurence H, Maki, Robert G, Reinke, Denise, Patel, Shreyaskumar

“…Patients with advanced sarcomas have a poor prognosis and few treatment options that improve overall survival. Chemotherapy and targeted therapies offer…”
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Patient-reported outcomes in individuals with advanced gastrointestinal stromal tumor treated with ripretinib in the fourth-line setting: analysis from the phase 3 INVICTUS trial by Schöffski, Patrick, George, Suzanne, Heinrich, Michael C, Zalcberg, John R, Bauer, Sebastian, Gelderblom, Hans, Serrano, César, Jones, Robin L, Attia, Steven, D'Amato, Gina, Chi, Ping, Reichardt, Peter, Becker, Claus, Shi, Kelvin, Meade, Julie, Ruiz-Soto, Rodrigo, Blay, Jean-Yves, von Mehren, Margaret

“…Ripretinib is a novel switch-control kinase inhibitor that inhibits KIT and PDGFRA signaling. In the INVICTUS phase 3 trial, ripretinib increased median…”
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A Retrospective Analysis of the Efficacy of Immunotherapy in Metastatic Soft-Tissue Sarcomas by Monga, Varun, Skubitz, Keith M, Maliske, Seth, Mott, Sarah L, Dietz, Hilary, Hirbe, Angela C, Van Tine, Brian A, Oppelt, Peter, Okuno, Scott, Robinson, Steven, O'Connor, Madeline, Seetharam, Mahesh, Attia, Steven, Charlson, John, Agulnik, Mark, Milhem, Mohammed

“…Although checkpoint inhibitors have been approved in multiple cancers, they are still under investigation in soft tissue sarcoma (STS). We conducted a…”
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A phase II trial of regorafenib in patients with advanced Ewing sarcoma and related tumors of soft tissue and bone: SARC024 trial results by Attia, Steven, Bolejack, Vanessa, Ganjoo, Kristen N., George, Suzanne, Agulnik, Mark, Rushing, Daniel, Loggers, Elizabeth T., Livingston, Michael B., Wright, Jennifer, Chawla, Sant P., Okuno, Scott H., Reinke, Denise K., Riedel, Richard F., Davis, Lara E., Ryan, Christopher W., Maki, Robert G.

“…Background Regorafenib is one of several FDA‐approved cancer therapies targeting multiple tyrosine kinases. However, there are few subtype‐specific data…”
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The Volume-Outcome Relationship in Retroperitoneal Soft Tissue Sarcoma: Evidence of Improved Short- and Long-Term Outcomes at High-Volume Institutions by Wasif, Nabil, Ashman, Jonathan B., Gabriel, Emmanuel, Gray, Richard J., Neville, Matthew, Bagaria, Sanjay P., Attia, Steven

“…Background. We sought to study the association between RPS case volume and outcomes. Although a relationship has been demonstrated between case volume and…”
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Pharmacokinetics of dacarbazine and unesbulin and CYP1A2‐mediated drug interactions in patients with leiomyosarcoma by Gao, Lan, Kaushik, Diksha, Van Tine, Brian A., Ingham, Matthew A., Attia, Steven, Meyer, Christian F., Schwartz, Gary K., Maliakal, Pius, Baird, John D., Ma, Jiyuan, Barrett, Rosemary, D'Silva, Dhiren, O'Keefe, Kylie, Kong, Ronald

“…Unesbulin is being investigated in combination with dacarbazine (DTIC) as a potential therapeutic agent in patients with advanced leiomyosarcoma (LMS). This…”
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Clinical activity of pembrolizumab (P) in undifferentiated pleomorphic sarcoma (UPS) and dedifferentiated/pleomorphic liposarcoma (LPS): Final results of SARC028 expansion cohorts by Burgess, Melissa Amber, Bolejack, Vanessa, Schuetze, Scott, Van Tine, Brian Andrew, Attia, Steven, Riedel, Richard F., Hu, James S, Davis, Lara Emily, Okuno, Scott H., Priebat, Dennis A., Movva, Sujana, Reed, Damon R., D'Angelo, Sandra P., Lazar, Alexander J., Keung, Emily Zhi-Yun, Reinke, Denise K., Baker, Laurence H., Maki, Robert G., Patel, Shreyaskumar, Tawbi, Hussein Abdul-Hassan

“…Abstract only 11015 Background: Immune checkpoint inhibitors have demonstrated activity in multiple tumor types but their activity in soft tissue sarcomas…”
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Association Between Programmed Death-Ligand 1 Expression and the Vascular Endothelial Growth Factor Pathway in Angiosarcoma by Bagaria, Sanjay P, Gatalica, Zoran, Maney, Todd, Serie, Daniel, Parasramka, Mansi, Attia, Steven, Krishna, Murli, Joseph, Richard W

“…Angiosarcoma is a vascular malignancy associated with a poor prognosis and chemotherapy resistance. The tumor immune microenvironment of angiosarcoma has not…”
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Improving Long-Term Outcomes for Patients with Extra-Abdominal Soft Tissue Sarcoma Regionalization to High-Volume Centers, Improved Compliance with Guidelines or Both? by Attia, Steven, Ashman, Jonathan B., Gray, Richard J., Chang, Yu-Hui, Bagaria, Sanjay P., Wasif, Nabil

“…Introduction. Optimization of outcomes of extra-abdominal STS is not clearly understood. We sought to determine whether hospital surgical volume and adherence…”
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Phase III, randomized, double blind, placebo-controlled trial of sorafenib in desmoid tumors (Alliance A091105) by Gounder, Mrinal M., Mahoney, Michelle R., Van Tine, Brian Andrew, Ravi, Vinod, Attia, Steven, Deshpande, Hari Anant, Gupta, Abha A., Milhem, Mohammed M., Conry, Robert Martin, Movva, Sujana, Pishvaian, Michael J., Crawford, Jeffrey, Sabagh, Tarek, Maki, Robert G., Tap, William D., Lefkowitz, Robert A, Agaram, Narasimhan P, Wright, John Joseph, Dueck, Amylou C., Schwartz, Gary K.

“…Abstract only…”
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Clinical outcomes of patients with advanced synovial sarcoma or myxoid/round cell liposarcoma treated at major cancer centers in the United States by Pollack, Seth M., Somaiah, Neeta, Araujo, Dejka M., Druta, Mihaela, Van Tine, Brian A., Burgess, Melissa A., Chawla, Sant P., Seetharam, Mahesh, Okuno, Scott H., Bohac, Chet, Chen, Michael, Yurasov, Sergey, Attia, Steven

“…Background Outcomes data regarding advanced synovial sarcoma (SS) and myxoid/round cell liposarcoma (MRCL) are limited, consisting primarily of retrospective…”
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Randomized, Double-Blinded Phase II Evaluation of Docetaxel with or without Doxercalciferol in Patients with Metastatic, Androgen-Independent Prostate Cancer by Attia, Steven, Eickhoff, Jens, Wilding, George, McNeel, Douglas, Blank, Jules, Ahuja, Harish, Jumonville, Alcee, Eastman, Michael, Shevrin, Daniel, Glode, Michael, Alberti, Dona, Staab, Mary Jane, Horvath, Dottie, Straus, Jane, Marnocha, Rebecca, Liu, Glenn

“…Purpose: Docetaxel is standard of care for androgen-independent prostate cancer (AIPC). Doxercalciferol (1α-hydroxyvitamin D2) had modest activity in phase…”
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Phase II trial of daily oral perillyl alcohol (NSC 641066) in treatment-refractory metastatic breast cancer by Bailey, Howard H., Attia, Steven, Love, Richard R., Fass, Terri, Chappell, Rick, Tutsch, Kendra, Harris, Linda, Jumonville, Alcee, Hansen, Richard, Shapiro, Gary R., Stewart, James A.

“…Purpose Perillyl alcohol (POH) is a naturally occurring lipid with preclinical activity against mammary carcinomas. We conducted a phase II multi-institutional…”
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Clinical Activity of Pazopanib in Metastatic Extraosseous Ewing Sarcoma by Attia, Steven, Okuno, Scott H, Robinson, Steven I, Webber, Nicholas P, Indelicato, Daniel J, Jones, Robin L, Bagaria, Sanjay P, Jones, Robin L, Sherman, Courtney, Kozak, Kevin R, Cortese, Cherise M, McFarland, Thomas, Trent, Jonathan C, Maki, Robert G

“…We report a response to pazopanib in a 69-year-old man with heavily pre-treated metastatic extraosseous Ewing sarcoma in addition to molecular profiling of his…”
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Dedifferentiated Liposarcoma of the Esophagus: A Case Report and Selected Review of the Literature by Brett, Christopher L, Miller, Daniel H, Jiang, Liuyan, Wolfsen, Herbert C, Attia, Steven, Hintenlang, Lauren, Jagadesh, Niveditha, Miller, Robert C

“…Soft tissue sarcomas of the esophagus represent an extremely rare cause of esophageal masses, and an even smaller proportion of these tumors represent…”
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Comprehensive Genomic Profiling of a Rare Thyroid Follicular Dendritic Cell Sarcoma by Davila, Jaime I, Starr, Jason S, Attia, Steven, Wang, Chen, Knudson, Ryan A, Necela, Brian M, Sarangi, Vivekananda, Sun, Zhifu, Ren, Yingxue, Casler, John D, Menke, David M, Oliver, Gavin R, Joseph, Richard W, Copland, John A, Parker, Alexander S, Kocher, Jean-Pierre A, Thompson, E Aubrey, Smallridge, Robert C, Asmann, Yan W

“…We previously reported an extremely rare case of follicular dendritic cell sarcoma (FDCS) presented as a thyroid mass. Given the rarity of this disease, there…”
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Recurrent myxoinflammatory fibroblastic sarcoma: a case report by Jagadesh, Niveditha, Miller, Daniel H., Schenk, William, Attia, Steven, Sherman, Courtney E., Cortese, Cherise, May, Byron C., Miller, Robert C.

“…Key Clinical Message Myxoinflammatory fibroblastic sarcoma is a rare sarcoma which typically presents in the extremities and is treated by definitive surgery…”
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High Grade Leiomyosarcoma Mimicking a Recurrent Angiomyxoma in the Perineum by Sood, Neha, Swaika, Abhisek, Hanooshi, Bashar, Waldorf, James, Peterson, Jennifer, Wu, Kevin, Attia, Steven, Dinh, Tri A

“…Perineal leiomyosarcoma is an extremely rare and aggressive cancer with a high metastatic potential and no defined standard treatment. There are only a few…”
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Langerhan's Cell Sarcoma: Two Case Reports by Kaleem, Tasneem A, Schild, Michael H, Miller, Daniel, Jha, Asit, Cortese, Cherise, Attia, Steven, Miller, Robert C

“…Langerhan's cell sarcoma (LCS) is a rare neoplasm with a poor prognosis. To our knowledge, only sixty-six cases have been published. We discuss two patients…”
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Evaluation of mRNA by Q-RTPCR and protein expression by AQUA of the M2 subunit of ribonucleotide reductase (RRM2) in human tumors by Kolesar, Jill, Huang, Wei, Eickhoff, Jens, Hahn, Kristine, Alberti, Dona, Attia, Steven, Schelman, William, Holen, Kyle, Traynor, Anne, Ivy, Percy, Wilding, George

“…Purpose The purpose of this study was to evaluate baseline RRM2 protein and gene expression in tumors of patients receiving 3-AP. Methods Tumor blocks from…”
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