Search Results - "Atteya, Reham"
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Topoisomerase-mediated chromosomal break repair: an emerging player in many games
Published in Nature reviews. Cancer (01-03-2015)“…Key Points Topoisomerases are elegant biological tools that have evolved to resolve nucleic acid entanglements during replication, transcription and…”
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Unveiling the microevolution of antimicrobial resistance in selected Pseudomonas aeruginosa isolates from Egyptian healthcare settings: A genomic approach
Published in Scientific reports (05-07-2024)“…The incidence of Pseudomonas aeruginosa infections in healthcare environments, particularly in low-and middle-income countries, is on the rise. The purpose of…”
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3
Rad5, HLTF, and SHPRH: A Fresh View of an Old Story
Published in Trends in genetics (01-08-2018)“…Not only have helicase-like transcription factor (HLTF) and SNF2 histone-linker PHD-finger RING-finger helicase (SHPRH) proved to be important players in…”
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Genomic dynamics of high-risk carbapenem-resistant klebsiella pneumoniae clones carrying hypervirulence determinants in Egyptian clinical settings
Published in BMC infectious diseases (22-10-2024)“…Ongoing studies have revealed the global prevalence of severe infections caused by the hypervirulent strains of Klebsiella pneumoniae (K. pneumoniae)…”
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Isolation, Characterization, and Genomic Analysis of Three Novel E. coli Bacteriophages That Effectively Infect E. coli O18
Published in Microorganisms (Basel) (09-03-2022)“…( ) is one of the most common pathogenic bacteria worldwide. Avian pathogenic (APEC) causes severe systemic disease in poultry (Colibacillosis), and…”
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Impact of circ-0000221 in the Pathogenesis of Hepatocellular via Modulation of miR-661-PTPN11 mRNA Axis
Published in Pharmaceutics (06-01-2022)“…Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death in Egypt. A deep understanding of the molecular events occurring in HCC can…”
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7
PARPing for balance in the homeostasis of poly(ADP-ribosyl)ation
Published in Seminars in cell & developmental biology (01-03-2017)“…Despite more than 50 years of research, the vast majority of the biology of poly(ADP-ribosyl)ation (PARylation) still remains a gross mystery. Originally…”
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Chemical screening identifies the β-Carboline alkaloid harmine to be synergistically lethal with doxorubicin
Published in Mechanisms of ageing and development (01-01-2017)“…•Synergistic cytotoxicity of harmine and doxorubicin on MCF-7 breast cancer cells.•Harmine does not enhance the cytotoxicity of Etoposide or…”
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High Temperature Drives Topoisomerase Mediated Chromosomal Break Repair Pathway Choice
Published in Cancers (12-05-2021)“…Cancer-causing mutations often arise from inappropriate DNA repair, yet acute exposure to DNA damage is widely used to treat cancer. The challenge remains in…”
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A role for Rad5 in ribonucleoside monophosphate (rNMP) tolerance
Published in Life science alliance (01-10-2021)“…Ribonucleoside monophosphate (rNMP) incorporation in genomic DNA poses a significant threat to genomic integrity. In addition to repair, DNA damage tolerance…”
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