Search Results - "Attems, J."

Review: Sporadic cerebral amyloid angiopathy by Attems, J., Jellinger, K., Thal, D. R., Van Nostrand, W.

“…J. Attems, K. Jellinger, D. R. Thal and W. Van Nostrand (2011) Neuropathology and Applied Neurobiology37, 75–93
Sporadic cerebral amyloid angiopathy Cerebral…”
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CD8+ T-cells infiltrate Alzheimer’s disease brains and regulate neuronal- and synapse-related gene expression in APP-PS1 transgenic mice by Unger, M.S., Li, E., Scharnagl, L., Poupardin, R., Altendorfer, B., Mrowetz, H., Hutter-Paier, B., Weiger, T.M., Heneka, M.T., Attems, J., Aigner, L.

“…•CD8+ T-cells infiltrate the brain in aging and human AD pathology.•CD8+ T-cells can successfully be ablated from blood and brain using an anti-CD8 antibody…”
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SIRT1, miR-132 and miR-212 link human longevity to Alzheimer’s Disease by Hadar, A., Milanesi, E., Walczak, M., Puzianowska-Kuźnicka, M., Kuźnicki, J., Squassina, A., Niola, P., Chillotti, C., Attems, J., Gozes, I., Gurwitz, D.

“…Alzheimer’s Disease (AD) is the most common cause of dementia in the elderly. Centenarians – reaching the age of >100 years while maintaining good cognitive…”
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Neuropathological correlates of dopaminergic imaging in Alzheimer's disease and Lewy body dementias by COLLOBY, Sean J, MCPARLAND, Shane, O'BRIEN, John T, ATTEMS, Johannes

“…Investigation of dopaminergic transporter loss in vivo using (123)I-N-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl) nortropane single photon emission computed…”
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Correlations between cortical and subcortical tau pathology by Attems, J., Thomas, A., Jellinger, K.

“…J. Attems, A. Thomas and K. Jellinger (2012) Neuropathology and Applied Neurobiology38, 582–590 Correlations between cortical and subcortical tau pathology…”
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Neuropathological evaluation of mixed dementia by Jellinger, K.A, Attems, J

“…Abstract Mixed dementia (MD) refers to a combination of definite Alzheimer disease (AD) and vascular encephalopathy, but the distinction between both disorders…”
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Concomitant LATE‐NC in Alzheimer's disease is not associated with increased tau or amyloid‐β pathological burden by McAleese, K. E., Walker, L., Erskine, D., Johnson, M., Koss, D., Thomas, A. J., Attems, J.

“…The presence of Limbic‐predominant age‐related TDP‐43 encephalopathy neuropathological change (LATE‐NC) is not associated with an increase in the burden of…”
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Microglia depletion diminishes key elements of the leukotriene pathway in the brain of Alzheimer's Disease mice by Michael, J, Unger, M S, Poupardin, R, Schernthaner, P, Mrowetz, H, Attems, J, Aigner, L

“…Leukotrienes (LTs) contribute to the neuropathology of chronic neurodegenerative disorders including Alzheimer's Disease (AD), where they mediate…”
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Systems proteomic analysis reveals that clusterin and tissue inhibitor of metalloproteinases 3 increase in leptomeningeal arteries affected by cerebral amyloid angiopathy by Manousopoulou, A., Gatherer, M., Smith, C., Nicoll, J. A. R., Woelk, C. H., Johnson, M., Kalaria, R., Attems, J., Garbis, S. D., Carare, R. O.

“…Aims Amyloid beta (Aβ) accumulation in the walls of leptomeningeal arteries as cerebral amyloid angiopathy (CAA) is a major feature of Alzheimer's disease. In…”
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Neurofibrillary tangle-predominant dementia: comparison with classical Alzheimer disease by Jellinger, K A, Attems, J

“…Neurofibrillary tangle predominant dementia (NFTPD) is a subset of late onset dementia, clinically different from traditional "plaque and tangle" Alzheimer…”
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Lysosomal cathepsin D is upregulated in Alzheimer's disease neocortex and may be a marker for neurofibrillary degeneration by Chai, Yuek Ling, Chong, Joyce R., Weng, Jiaju, Howlett, David, Halsey, Andrea, Lee, Jasinda H., Attems, Johannes, Aarsland, Dag, Francis, Paul T., Chen, Christopher P., Lai, Mitchell K.P.

“…Alzheimer's disease (AD) is characterized by accumulation of β‐amyloid plaques (AP) and neurofibrillary tangles (NFT) in the cortex, together with synaptic…”
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Olfactory tau pathology in Alzheimer disease and mild cognitive impairment by Attems, J, Jellinger, K A

“…To examine the occurrence of tau pathology in the olfactory system in aged subjects and its relation to the severity of Alzheimer disease (AD) pathology. 273…”
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Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease by WATABE-RUDOLPH, M, SONG, Z, ATTEMS, J, JELLINGER, K. A, KESTLER, H. A, ARNIM, C. A. F. Von, RUDOLPH, K. L, LAUSSER, L, SCHNACK, C, BEGUS-NAHRMANN, Y, SCHEITHAUER, M.-O, RETTINGER, G, OTTO, M, TUMANI, H, THAI, D. R

“…DNA damage accumulation in brain is associated with the development of Alzheimer disease (AD), but newly identified protein markers of DNA damage have not been…”
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Cholinergic deficits and galaninergic hyperinnervation of the nucleus basalis of Meynert in Alzheimer’s disease and Lewy body disorders by Alexandris, A. S., Walker, L., Liu, A. K. L., McAleese, K. E., Johnson, M., Pearce, R. K. B., Gentleman, S. M., Attems, J.

“…Aims Galanin is a highly inducible neuroprotective neuropeptide and in Alzheimer’s disease (AD), a network of galaninergic fibres has been reported to…”
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The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease by Attems, J., Jellinger, K. A.

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Neuropathological and biochemical investigation of Hereditary Ferritinopathy cases with ferritin light chain mutation: Prominent protein aggregation in the absence of major mitochondrial or oxidative stress by Kurzawa‐Akanbi, M., Keogh, M., Tsefou, E., Ramsay, L., Johnson, M., Keers, S., WSA Ochieng, L., McNair, A., Singh, P., Khan, A., Pyle, A., Hudson, G., Ince, P. G., Attems, J., Burn, J., Chinnery, P. F., Morris, C. M.

“…Aims Neuroferritinopathy (NF) or hereditary ferritinopathy (HF) is an autosomal dominant movement disorder due to mutation in the light chain of the iron…”
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Unfolded protein response is activated in Lewy body dementias by Baek, Jean-Ha, Whitfield, David, Howlett, David, Francis, Paul, Bereczki, Erika, Ballard, Clive, Hortobágyi, Tibor, Attems, Johannes, Aarsland, Dag

“…Aim The unfolded protein response (UPR) is a pro‐survival defence mechanism induced during periods of endoplasmic reticulum stress, and it has recently emerged…”
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Cerebral amyloid angiopathy in Lewy body disease by Jellinger, K. A., Attems, J.

“…While Alzheimer and Lewy body pathologies are discussed as major substrates of dementia in Parkinson’s disease (PD/Lewy body disease of brainstem type), the…”
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Unexpectedly low prevalence of intracerebral hemorrhages in sporadic cerebral amyloid angiopathy: An autopsy study by Attems, J., Lauda, F., Jellinger, K. A.

“…In a retrospective study of a consecutive autopsy series of 2060 elderly subjects (mean age 78.5 ± 6.8 SD years), sporadic cerebral amyloid angiopathy (CAA) of…”
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Exome sequencing in dementia with Lewy bodies by Keogh, M J, Kurzawa-Akanbi, M, Griffin, H, Douroudis, K, Ayers, K L, Hussein, R I, Hudson, G, Pyle, A, Cordell, H J, Attems, J, McKeith, I G, O'Brien, J T, Burn, D J, Morris, C M, Thomas, A J, Chinnery, P F

“…Dementia with Lewy bodies (DLB) is the second most common form of degenerative dementia. Siblings of affected individuals are at greater risk of developing…”
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