Search Results - "Atsushi NATSUME"
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Podoplanin: An emerging cancer biomarker and therapeutic target
Published in Cancer science (01-05-2018)“…Podoplanin (PDPN) is a transmembrane receptor glycoprotein that is upregulated on transformed cells, cancer associated fibroblasts and inflammatory macrophages…”
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A rapid and easy-to-use spinal muscular atrophy screening tool based on primers with high specificity and amplification efficiency for SMN1 combined with single-stranded tag hybridization assay
Published in PloS one (01-08-2024)“…Spinal muscular atrophy (SMA) is an intractable neuromuscular disorder primarily caused by homozygous deletions in exon 7 of the SMN1 gene. Early diagnosis and…”
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3
Overview of DNA methylation in adult diffuse gliomas
Published in Brain tumor pathology (01-04-2019)“…Adult diffuse gliomas form a heterogeneous group of tumors of the central nervous system that vary greatly in histology and prognosis. A significant advance…”
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Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment
Published in Nature communications (06-12-2016)“…Targeting self-renewal is an important goal in cancer therapy and recent studies have focused on Notch signalling in the maintenance of stemness of glioma stem…”
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5
Mutational landscape and clonal architecture in grade II and III gliomas
Published in Nature genetics (01-05-2015)“…Seishi Ogawa, Atsushi Natsume and colleagues report analyses of large sets of sequence data of grade II and III gliomas. They find three distinct subtypes of…”
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Lack of GD3 synthase (St8sia1) attenuates malignant properties of gliomas in genetically engineered mouse model
Published in Cancer science (01-09-2021)“…High expression of gangliosides GD3 and GD2 is observed in human gliomas. The functions of GD3 and GD2 in malignant properties have been reported in glioma…”
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7
Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1)
Published in International journal of clinical oncology (01-02-2021)“…Background To promote precision oncology in clinical practice, the Japanese Society of Medical Oncology, the Japanese Society of Clinical Oncology, and the…”
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Importance of Hydrostatic Pressure and Irrigation for Hemostasis in Neuroendoscopic Surgery
Published in Neurologia medico-chirurgica (2021)“…Recently neurosurgical operations have been carried out with water irrigation such as endoscopic third ventriculostomy and tumor resections in ventricles…”
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All-in-One Nanowire Assay System for Capture and Analysis of Extracellular Vesicles from an ex Vivo Brain Tumor Model
Published in ACS nano (14-02-2023)“…Extracellular vesicles (EVs) have promising potential as biomarkers for early cancer diagnosis. The EVs have been widely studied as biological cargo containing…”
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10
Novel Human NK Cell Line Carrying CAR Targeting EGFRvIII Induces Antitumor Effects in Glioblastoma Cells
Published in Anticancer research (01-09-2018)“…Natural killer (NK) cells are considered potential antitumor effector cells. The aim of this study was to establish a novel type of a chimeric antigen receptor…”
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Aberrant Transcriptional Regulation of Super-enhancers by RET Finger Protein-histone Deacetylase 1 Complex in Glioblastoma: Chemoresistance to Temozolomide
Published in Neurologia medico-chirurgica (2019)“…Glioblastoma (GBM), the most common primary brain tumor, is the most aggressive human cancers, with a median survival rate of only 14.6 months. Temozolomide…”
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12
Epigenetic dysregulation in glioma
Published in Cancer science (01-04-2014)“…Given that treatment options for patients with glioblastoma are limited, much effort has been made to clarify the underlying mechanisms of gliomagenesis…”
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13
Urinary MicroRNA-Based Diagnostic Model for Central Nervous System Tumors Using Nanowire Scaffolds
Published in ACS applied materials & interfaces (21-04-2021)“…There are no accurate mass screening methods for early detection of central nervous system (CNS) tumors. Recently, liquid biopsy has received a lot of…”
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Effects of aspirin and heparin treatment on perioperative outcomes in patients with Moyamoya disease
Published in Acta neurochirurgica (01-05-2021)“…Background When superficial temporal artery-middle cerebral artery bypass is combined with indirect methods (e.g., revascularization surgery) to treat Moyamoya…”
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A randomized, double-blind, phase III trial of personalized peptide vaccination for recurrent glioblastoma
Published in Neuro-oncology (Charlottesville, Va.) (19-02-2019)“…Abstract Background We conducted a phase III trial of personalized peptide vaccination (PPV) for human leukocyte antigen (HLA)-A24+ recurrent glioblastoma to…”
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Establishment of in-hospital clinical network for patients with neurofibromatosis type 1 in Nagoya University Hospital
Published in Scientific reports (07-06-2021)“…Neurofibromatosis type 1 (NF1) is a genetic multisystem disorder. Clinicians must be aware of the diverse clinical features of this disorder in order to…”
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Current Trends in Targeted Therapies for Glioblastoma Multiforme
Published in Neurology Research International (01-01-2012)“…Glioblastoma multiforme (GBM) is one of the most frequently occurring tumors in the central nervous system and the most malignant tumor among gliomas. Despite…”
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Navigated repetitive transcranial magnetic stimulation as preoperative assessment in patients with brain tumors
Published in Scientific reports (03-06-2020)“…We aimed to investigate clinical parameters that affected the results of navigated repetitive transcranial magnetic stimulation (nrTMS) language mapping by…”
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Trautmann-focused mastoidectomy for a simple, safe presigmoid approach: technical note
Published in Journal of neurosurgery (01-03-2021)“…The presigmoid approach (PSA) is selected to obtain more lateral access to cerebellopontine angle tumors, brainstem cavernous malformations, or vertebrobasilar…”
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Effects of insular resection on interactions between cardiac interoception and emotion recognition
Published in Cortex (01-04-2021)“…The insular cortex is considered an important region for feeling emotions through interoception. Most studies that report the role of the insula in integrating…”
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