Search Results - "Atsuo, Ogura"
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Recent advancements in cloning by somatic cell nuclear transfer
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05-01-2013)“…Somatic cell nuclear transfer (SCNT) cloning is the sole reproductive engineering technology that endows the somatic cell genome with totipotency. Since the…”
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A New, Dynamic Era for Somatic Cell Nuclear Transfer?
Published in Trends in biotechnology (Regular ed.) (01-10-2016)“…Cloning animals by somatic cell nuclear transfer (SCNT) has remained an uncontrollable process for many years. High rates of embryonic losses, stillbirths, and…”
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Reprogramming of the histone H3.3 landscape in the early mouse embryo
Published in Nature structural & molecular biology (01-01-2021)“…Epigenetic reprogramming of the zygote involves dynamic incorporation of histone variant H3.3. However, the genome-wide distribution and dynamics of H3.3…”
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In memory of Dr. Ryuzo Yanagimachi (Yana) (1928–2023)
Published in Journal of Reproduction and Development (2024)Get full text
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Formation of spermatogonia and fertile oocytes in golden hamsters requires piRNAs
Published in Nature cell biology (01-09-2021)“…PIWI-interacting RNAs (piRNAs) support the germline by suppressing retrotransposons. Studies of the pathway in mice have strongly shaped the view that…”
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Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas
Published in Nature communications (01-05-2020)“…Somatic cell nuclear transfer (SCNT) in mammals is an inefficient process that is frequently associated with abnormal phenotypes, especially in placentas…”
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ROS Are Required for Mouse Spermatogonial Stem Cell Self-Renewal
Published in Cell stem cell (06-06-2013)“…Reactive oxygen species (ROS) generation is implicated in stem cell self-renewal in several tissues but is thought to be detrimental for spermatogenesis as…”
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Colorimetric detection of loop-mediated isothermal amplification reaction by using hydroxy naphthol blue
Published in BioTechniques (01-03-2009)“…Loop-mediated isothermal amplification (LAMP), a novel gene amplification method, enables the synthesis of larger amounts of both DNA and a visible…”
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In vitro production of functional sperm in cultured neonatal mouse testes
Published in Nature (London) (24-03-2011)“…Preserving sperm fertility Reproducing the complex process of spermatogenesis in vitro might lead to the development of new diagnostic and therapeutic…”
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Cloning Mice
Published in Cold Spring Harbor protocols (01-08-2017)“…Viable and fertile mice can be generated by somatic nuclear transfer into enucleated oocytes, presumably because the transplanted somatic cell genome becomes…”
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Editing the Genome of the Golden Hamster (Mesocricetus auratus)
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…The golden (Syrian) hamster (Mesocricetus auratus) is a small rodent belonging to the Cricetidae family. Golden hamsters have several unique characteristics…”
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Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryos Disrupts Post-Implantation Development
Published in Cell stem cell (06-09-2018)“…Animal cloning can be achieved through somatic cell nuclear transfer (SCNT), although the live birth rate is relatively low. Recent studies have identified…”
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Role of CD4 + T Cells in Allergic Airway Diseases: Learning from Murine Models
Published in International journal of molecular sciences (11-10-2020)“…The essential contribution of CD4 T cells in allergic airway diseases has been demonstrated, especially by using various murine models of antigen-induced…”
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CRISPR/Cas9-based genetic screen of SCNT-reprogramming resistant genes identifies critical genes for male germ cell development in mice
Published in Scientific reports (29-07-2021)“…Male germ cells undergo complex developmental processes eventually producing spermatozoa through spermatogenesis, although the molecular mechanisms remain…”
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PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos
Published in Nature (London) (21-06-2012)“…The binding of PGC7 to maternal chromatin, which is important for methylation maintenance during embryogenesis, is shown to be dependent on a particular…”
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Acrosin is essential for sperm penetration through the zona pellucida in hamsters
Published in Proceedings of the National Academy of Sciences - PNAS (04-02-2020)“…During natural fertilization, mammalian spermatozoa must pass through the zona pellucida before reaching the plasma membrane of the oocyte. It is assumed that…”
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A non-mosaic transchromosomic mouse model of down syndrome carrying the long arm of human chromosome 21
Published in eLife (29-06-2020)“…Animal models of Down syndrome (DS), trisomic for human chromosome 21 (HSA21) genes or orthologs, provide insights into better understanding and treatment…”
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Use of anti-inhibin monoclonal antibody for increasing the litter size of mouse strains and its application to in vivo-genome editing technology
Published in Biology of reproduction (09-08-2022)“…The litter size of mouse strains is determined by the number of oocytes naturally ovulated. Many attempts have been made to increase litter sizes by…”
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Noncanonical imprinting sustains embryonic development and restrains placental overgrowth
Published in Genes & development (01-04-2022)“…Genomic imprinting regulates parental origin-dependent monoallelic gene expression. It is mediated by either germline differential methylation of DNA…”
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In vitro production of fertile sperm from murine spermatogonial stem cell lines
Published in Nature communications (13-09-2011)“…Spermatogonial stem cells (SSCs) are the only stem cells in the body that transmit genetic information to the next generation. The long-term propagation of…”
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