Search Results - "Atsma, Douwe E"

Left Atrial Size and Function in Hypertrophic Cardiomyopathy Patients and Risk of New-Onset Atrial Fibrillation by Debonnaire, Philippe, Joyce, Emer, Hiemstra, Yasmine, Mertens, Bart J, Atsma, Douwe E, Schalij, Martin J, Bax, Jeroen J, Delgado, Victoria, Marsan, Nina Ajmone

“…BACKGROUND—The value of left atrial (LA) diameter, volume, and strain to risk stratify hypertrophic cardiomyopathy patients for new-onset atrial fibrillation…”
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Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function by Birket, Matthew J., Ribeiro, Marcelo C., Kosmidis, Georgios, Ward, Dorien, Leitoguinho, Ana Rita, van de Pol, Vera, Dambrot, Cheryl, Devalla, Harsha D., Davis, Richard P., Mastroberardino, Pier G., Atsma, Douwe E., Passier, Robert, Mummery, Christine L.

“…Maximizing baseline function of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) is essential for their effective application in models of cardiac…”
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Impact of genotype on clinical course in arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated mutation carriers by Bhonsale, Aditya, Groeneweg, Judith A, James, Cynthia A, Dooijes, Dennis, Tichnell, Crystal, Jongbloed, Jan D H, Murray, Brittney, te Riele, Anneline S J M, van den Berg, Maarten P, Bikker, Hennie, Atsma, Douwe E, de Groot, Natasja M, Houweling, Arjan C, van der Heijden, Jeroen F, Russell, Stuart D, Doevendans, Pieter A, van Veen, Toon A, Tandri, Harikrishna, Wilde, Arthur A, Judge, Daniel P, van Tintelen, J Peter, Calkins, Hugh, Hauer, Richard N

“…We sought to determine the influence of genotype on clinical course and arrhythmic outcome among arrhythmogenic right ventricular dysplasia/cardiomyopathy…”
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Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: Disease mechanisms and pharmacological rescue by Zhang, Miao, D'Aniello, Cristina, Verkerk, Arie O., Wrobel, Eva, Frank, Stefan, Ward-van Oostwaard, Dorien, Piccini, Ilaria, Freund, Christian, Rao, Jyoti, Seebohm, Guiscard, Atsma, Douwe E., Schulze-Bahr, Eric, Mummery, Christine L., Greber, Boris, Bellin, Milena

“…Jervell and Lange-Nielsen syndrome (JLNS) is one of the most severe life-threatening cardiac arrhythmias. Patients display delayed cardiac repolarization,…”
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Clinical Presentation, Long-Term Follow-Up, and Outcomes of 1001 Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patients and Family Members by Groeneweg, Judith A, Bhonsale, Aditya, James, Cynthia A, te Riele, Anneline S, Dooijes, Dennis, Tichnell, Crystal, Murray, Brittney, Wiesfeld, Ans C P, Sawant, Abhishek C, Kassamali, Bina, Atsma, Douwe E, Volders, Paul G, de Groot, Natasja M, de Boer, Karin, Zimmerman, Stefan L, Kamel, Ihab R, van der Heijden, Jeroen F, Russell, Stuart D, Jan Cramer, Maarten, Tedford, Ryan J, Doevendans, Pieter A, van Veen, Toon A, Tandri, Harikrishna, Wilde, Arthur A, Judge, Daniel P, van Tintelen, J Peter, Hauer, Richard N, Calkins, Hugh

“…Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a progressive cardiomyopathy. We aimed to define long-term outcome in a transatlantic…”
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Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies by Brandão, Karina O, Tabel, Viola A, Atsma, Douwe E, Mummery, Christine L, Davis, Richard P

“…It is now a decade since human induced pluripotent stem cells (hiPSCs) were first described. The reprogramming of adult somatic cells to a pluripotent state…”
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Post-ischemic Myocardial Inflammatory Response: A Complex and Dynamic Process Susceptible to Immunomodulatory Therapies by Pluijmert, Niek J, Atsma, Douwe E, Quax, Paul H A

“…Following acute occlusion of a coronary artery causing myocardial ischemia and implementing first-line treatment involving rapid reperfusion, a dynamic and…”
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Annexin A5 reduces infarct size and improves cardiac function after myocardial ischemia-reperfusion injury by suppression of the cardiac inflammatory response by de Jong, Rob C. M., Pluijmert, Niek J., de Vries, Margreet R., Pettersson, Knut, Atsma, Douwe E., Jukema, J. Wouter, Quax, Paul H. A.

“…Annexin A5 (AnxA5) is known to have anti-inflammatory and anti-apoptotic properties. Inflammation and apoptosis are key processes in post-ischemic cardiac…”
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The Impact of Obesity and Lifestyle on the Immune System and Susceptibility to Infections Such as COVID-19 by de Frel, Daan L, Atsma, Douwe E, Pijl, Hanno, Seidell, Jacob C, Leenen, Pieter J M, Dik, Willem A, van Rossum, Elisabeth F C

“…COVID-19 is a global challenge to healthcare. Obesity is common in patients with COVID-19 and seems to aggravate disease prognosis. In this review we explore…”
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Facilitators of and Barriers to Lifestyle Support and eHealth Solutions: Interview Study Among Health Care Professionals Working in Cardiac Care by Cohen Rodrigues, Talia R, de Buisonjé, David R, Keesman, Mike, Reijnders, Thomas, van der Geer, Jessica E, Janssen, Veronica R, Kraaijenhagen, Roderik A, Atsma, Douwe E, Evers, Andrea W M

“…Background Cardiovascular diseases (CVDs) pose a significant health threat and reduce both people’s life expectancy and quality of life. Healthy living is a…”
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Hypercholesterolemia affects cardiac function, infarct size and inflammation in APOE3-Leiden mice following myocardial ischemia-reperfusion injury by Pluijmert, Niek J, den Haan, Melina C, van Zuylen, Vanessa L, Steendijk, Paul, de Boer, Hetty C, van Zonneveld, Anton J, Fibbe, Willem E, Schalij, Martin J, Quax, Paul H A, Atsma, Douwe E

“…Hypercholesterolemia is a major risk factor for ischemic heart disease including acute myocardial infarction. However, long-term effects of…”
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Clarifying responsibility: professional digital health in the doctor-patient relationship, recommendations for physicians based on a multi-stakeholder dialogue in the Netherlands by Silven, Anna V, van Peet, Petra G, Boers, Sarah N, Tabak, Monique, de Groot, Aviva, Hendriks, Djoke, van Os, Hendrikus J A, Bonten, Tobias N, Atsma, Douwe E, de Graaf, Tycho J, Sombroek, Mirjam P, Chavannes, Niels H, Villalobos-Quesada, María

“…Implementation of digital health (eHealth) generally involves adapting pre-established and carefully considered processes or routines, and still raises…”
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Generation of two human induced pluripotent stem cell lines, LUMCi020-A and LUMCi021-A, from two patients with Catecholaminergic Polymorphic Ventricular Tachycardia carrying heterozygous mutations in the RYR2 gene by Meraviglia, Viviana, Arendzen, Christiaan H., Freund, Christian, Atsma, Douwe E., Mummery, Christine L., Bellin, Milena

“…Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is a malignant channelopathy associated with exercise- and stress-induced cardiac sudden death…”
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Intramyocardial Injection of Autologous Bone Marrow-Derived Ex Vivo Expanded Mesenchymal Stem Cells in Acute Myocardial Infarction Patients is Feasible and Safe up to 5 Years of Follow-up by Rodrigo, Sander F., van Ramshorst, Jan, Hoogslag, Georgette E., Boden, Helèn, Velders, Matthijs A., Cannegieter, Suzanne C., Roelofs, Helene, Al Younis, Imad, Dibbets-Schneider, Petra, Fibbe, Willem E., Zwaginga, Jaap Jan, Bax, Jeroen J., Schalij, Martin J., Beeres, Saskia L., Atsma, Douwe E.

“…In experimental studies, mesenchymal stem cell (MSC) transplantation in acute myocardial infarction (AMI) models has been associated with enhanced…”
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A Preoperative Virtual Reality App for Patients Scheduled for Cardiac Catheterization: Pre-Post Questionnaire Study Examining Feasibility, Usability, and Acceptability by Aardoom, Jiska J, Hilt, Alexander D, Woudenberg, Tamar, Chavannes, Niels H, Atsma, Douwe E

“…Pre- and postoperative anxiety is a common phenomenon associated with negative postoperative outcomes. Symptoms of posttraumatic stress disorder, such as fear,…”
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Participatory Development of an Integrated, eHealth-Supported, Educational Care Pathway (Diabetes Box) for People With Type 2 Diabetes: Development and Usability Study by de Frel, Daan Leonhard, Schroijen, Mariëlle A, Aardoom, Jiska J, van Gils, Wesley, Huisman, Sasja D, Janssen, Veronica R, Versluis, Anke, Kleinsmann, Maaike S, Atsma, Douwe E, Pijl, Hanno

“…Type 2 diabetes (T2D) tremendously affects patient health and health care globally. Changing lifestyle behaviors can help curb the burden of T2D. However,…”
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Human embryonic and fetal mesenchymal stem cells differentiate toward three different cardiac lineages in contrast to their adult counterparts by Ramkisoensing, Arti A, Pijnappels, Daniël A, Askar, Saïd F A, Passier, Robert, Swildens, Jim, Goumans, Marie José, Schutte, Cindy I, de Vries, Antoine A F, Scherjon, Sicco, Mummery, Christine L, Schalij, Martin J, Atsma, Douwe E

“…Mesenchymal stem cells (MSCs) show unexplained differences in differentiation potential. In this study, differentiation of human (h) MSCs derived from…”
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Human cues in eHealth to promote lifestyle change: An experimental field study to examine adherence to self-help interventions by Cohen Rodrigues, Talia R., de Buisonjé, David R., Reijnders, Thomas, Santhanam, Prabhakaran, Kowatsch, Tobias, Breeman, Linda D., Janssen, Veronica R., Kraaijenhagen, Roderik A., Atsma, Douwe E., Evers, Andrea W.M.

“…eHealth lifestyle interventions without human support (self-help interventions) are generally less effective, as they suffer from lower adherence levels. To…”
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Use Intention and User Expectations of Human-Supported and Self-Help eHealth Interventions: Internet-Based Randomized Controlled Trial by Cohen Rodrigues, Talia R, Reijnders, Thomas, Breeman, Linda D, Janssen, Veronica R, Kraaijenhagen, Roderik A, Atsma, Douwe E, Evers, Andrea Wm

“…Self-help eHealth interventions provide automated support to change health behaviors without any further human assistance. The main advantage of self-help…”
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Identifying barriers and facilitators to adopting healthier dietary choices in clinical care: a cross-sectional observational study by de Frel, Daan L, Wicks, Hope, Bakk, Zsuzsa, van Keulen, Nicole, Atsma, Douwe E, Janssen, Veronica R

“…Adopting healthier diets can drastically improve societal health. Our environment plays a crucial role in daily dietary choices and hospitals in particular can…”
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