Search Results - "Atochina, Elena"

Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice by Martinez, David R, Schäfer, Alexandra, Leist, Sarah R, De la Cruz, Gabriela, West, Ande, Atochina-Vasserman, Elena N, Lindesmith, Lisa C, Pardi, Norbert, Parks, Robert, Barr, Maggie, Li, Dapeng, Yount, Boyd, Saunders, Kevin O, Weissman, Drew, Haynes, Barton F, Montgomery, Stephanie A, Baric, Ralph S

“…The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2003 and SARS-CoV-2 in 2019 highlights the need to develop universal vaccination…”
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The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity by Zhang, Dapeng, Atochina-Vasserman, Elena N, Lu, Juncheng, Maurya, Devendra S, Xiao, Qi, Liu, Matthew, Adamson, Jasper, Ona, Nathan, Reagan, Erin K, Ni, Houping, Weissman, Drew, Percec, Virgil

“…Viral and synthetic vectors for delivery of nucleic acids impacted genetic nanomedicine by aiding the rapid development of the extraordinarily efficient…”
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Cell‐Based Drug Delivery and Use of Nano‐and Microcarriers for Cell Functionalization by Timin, Alexander S., Litvak, Maxim M., Gorin, Dmitry A., Atochina‐Vasserman, Elena N., Atochin, Dmitriy N., Sukhorukov, Gleb B.

“…Cell functionalization with recently developed various nano‐ and microcarriers for therapeutics has significantly expanded the application of cell therapy and…”
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c-Jun N-Terminal Kinases (JNKs) in Myocardial and Cerebral Ischemia/Reperfusion Injury by Shvedova, Maria, Anfinogenova, Yana, Atochina-Vasserman, Elena N, Schepetkin, Igor A, Atochin, Dmitriy N

“…In this article, we review the literature regarding the role of c-Jun N-terminal kinases (JNKs) in cerebral and myocardial ischemia/reperfusion injury…”
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Comprehensive characterisation of pulmonary and serum surfactant protein D in COPD by Winkler, Carla, Atochina-Vasserman, Elena N, Holz, Olaf, Beers, Michael F, Erpenbeck, Veit J, Krug, Norbert, Roepcke, Stefan, Lauer, Gereon, Elmlinger, Martin, Hohlfeld, Jens M

“…Pulmonary surfactant protein D (SP-D) is considered as a candidate biomarker for the functional integrity of the lung and for disease progression, which can be…”
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mTORC1 activation in lung mesenchyme drives sex- and age-dependent pulmonary structure and function decline by Obraztsova, Kseniya, Basil, Maria C., Rue, Ryan, Sivakumar, Aravind, Lin, Susan M., Mukhitov, Alexander R., Gritsiuta, Andrei I., Evans, Jilly F., Kopp, Meghan, Katzen, Jeremy, Robichaud, Annette, Atochina-Vasserman, Elena N., Li, Shanru, Carl, Justine, Babu, Apoorva, Morley, Michael P., Cantu, Edward, Beers, Michael F., Frank, David B., Morrisey, Edward E., Krymskaya, Vera P.

“…Lymphangioleiomyomatosis (LAM) is a rare fatal cystic lung disease due to bi-allelic inactivating mutations in tuberous sclerosis complex (TSC1/TSC2) genes…”
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S-nitrosylation of surfactant protein-D controls inflammatory function by Guo, Chang-Jiang, Atochina-Vasserman, Elena N, Abramova, Elena, Foley, Joseph P, Zaman, Aisha, Crouch, Erika, Beers, Michael F, Savani, Rashmin C, Gow, Andrew J

“…The pulmonary collectins, surfactant proteins A and D (SP-A and SP-D) have been implicated in the regulation of the innate immune system within the lung. In…”
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Folliculin Controls Lung Alveolar Enlargement and Epithelial Cell Survival through E-Cadherin, LKB1, and AMPK by Goncharova, Elena A., Goncharov, Dmitry A., James, Melane L., Atochina-Vasserman, Elena N., Stepanova, Victoria, Hong, Seung-Beom, Li, Hua, Gonzales, Linda, Baba, Masaya, Linehan, W. Marston, Gow, Andrew J., Margulies, Susan, Guttentag, Susan, Schmidt, Laura S., Krymskaya, Vera P.

“…Spontaneous pneumothoraces due to lung cyst rupture afflict patients with the rare disease Birt-Hogg-Dubé (BHD) syndrome, which is caused by mutations of the…”
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Rapamycin-independent IGF2 expression in Tsc2-null mouse embryo fibroblasts and human lymphangioleiomyomatosis cells by Himes, Blanca E, Obraztsova, Kseniya, Lian, Lurong, Shumyatcher, Maya, Rue, Ryan, Atochina-Vasserman, Elena N, Hur, Stella K, Bartolomei, Marisa S, Evans, Jilly F, Krymskaya, Vera P

“…Lymphangioleiomyomatosis (LAM) is a rare, almost exclusively female lung disease linked to inactivating mutations in tuberous sclerosis complex 2 (TSC2), a…”
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Screening Libraries to Discover Molecular Design Principles for the Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers Derived from Plant Phenolic Acids by Lu, Juncheng, Atochina-Vasserman, Elena N, Maurya, Devendra S, Shalihin, Muhammad Irhash, Zhang, Dapeng, Chenna, Srijay S, Adamson, Jasper, Liu, Matthew, Shah, Habib Ur Rehman, Shah, Honey, Xiao, Qi, Queeley, Bryn, Ona, Nathan A, Reagan, Erin K, Ni, Houping, Sahoo, Dipankar, Peterca, Mihai, Weissman, Drew, Percec, Virgil

“…Viral and synthetic vectors to deliver nucleic acids were key to the rapid development of extraordinarily efficient COVID-19 vaccines. The four-component lipid…”
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Biological Mechanisms of S-Nitrosothiol Formation and Degradation: How Is Specificity of S-Nitrosylation Achieved? by Massa, Christopher M., Liu, Ziping, Taylor, Sheryse, Pettit, Ashley P., Stakheyeva, Marena N., Korotkova, Elena, Popova, Valentina, Atochina-Vasserman, Elena N., Gow, Andrew J.

“…The modification of protein cysteine residues underlies some of the diverse biological functions of nitric oxide (NO) in physiology and disease. The formation…”
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Use of Submicron Vaterite Particles Serves as an Effective Delivery Vehicle to the Respiratory Portion of the Lung by Gusliakova, Olga, Atochina-Vasserman, Elena N, Sindeeva, Olga, Sindeev, Sergey, Pinyaev, Sergey, Pyataev, Nikolay, Revin, Viktor, Sukhorukov, Gleb B, Gorin, Dmitry, Gow, Andrew J

“…Nano- and microencapsulation has proven to be a useful technique for the construction of drug delivery vehicles for use in vascular medicine. However, the…”
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NOS2 is critical to the development of emphysema in Sftpd deficient mice but does not affect surfactant homeostasis by Knudsen, Lars, Atochina-Vasserman, Elena N, Guo, Chang-Jiang, Scott, Pamela A, Haenni, Beat, Beers, Michael F, Ochs, Matthias, Gow, Andrew J

“…Surfactant protein D (SP-D) has important immuno-modulatory properties. The absence of SP-D results in an inducible NO synthase (iNOS, coded by NOS2 gene)…”
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Aquaporin 11 insufficiency modulates kidney susceptibility to oxidative stress by Atochina-Vasserman, Elena N, Biktasova, Asel, Abramova, Elena, Cheng, Dong-Sheng, Polosukhin, Vasiliy V, Tanjore, Harikrishna, Takahashi, Saki, Sonoda, Hiroko, Foye, Liberty, Venkov, Christo, Ryzhov, Sergey V, Novitskiy, Sergey, Shlonimskaya, Natalia, Ikeda, Masahiro, Blackwell, Timothy S, Lawson, William E, Gow, Andrew J, Harris, Raymond C, Dikov, Mikhail M, Tchekneva, Elena E

“…Aquaporin 11 (AQP11) is a newly described member of the protein family of transport channels. AQP11 associates with the endoplasmic reticulum (ER) and is…”
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mRNA-based therapeutics: looking beyond COVID-19 vaccines by Parhiz, Hamideh, Atochina-Vasserman, Elena N, Weissman, Drew

“…Recent advances in mRNA technology and its delivery have enabled mRNA-based therapeutics to enter a new era in medicine. The rapid, potent, and transient…”
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Bivalent norovirus mRNA vaccine elicits cellular and humoral responses protecting human enteroids from GII.4 infection by Atochina-Vasserman, Elena N., Lindesmith, Lisa C., Mirabelli, Carmen, Ona, Nathan A., Reagan, Erin K., Brewer-Jensen, Paul D., Mercado-Lopez, Xiomara, Shahnawaz, Hamna, Meshanni, Jaclynn A., Baboo, Ishana, Mallory, Michael L., Zweigart, Mark R., May, Samantha R., Mui, Barbara L., Tam, Ying K., Wobus, Christiane E., Baric, Ralph S., Weissman, Drew

“…Nucleoside-modified mRNA-LNP vaccines have revolutionized vaccine development against infectious pathogens due to their ability to elicit potent humoral and…”
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Exposure to Silver Nanospheres Leads to Altered Respiratory Mechanics and Delayed Immune Response in an in Vivo Murine Model by Botelho, Danielle, Leo, Bey F, Massa, Christopher, Sarkar, Srijata, Tetley, Terry, Chung, Kian F, Chen, Shu, Ryan, Mary P, Porter, Alexandra, Atochina-Vasserman, Elena N, Zhang, Junfeng, Schwander, Stephan, Gow, Andrew J

“…Here we examine the organ level toxicology of both carbon black (CB) and silver nanoparticles (AgNP). We aim to determine metal-specific effects to respiratory…”
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Prophylactic fibrinolysis through selective dissolution of nascent clots by tPA-carrying erythrocytes by Muzykantov, Vladimir R, Murciano, Juan-Carlos, Medinilla, Sandra, Eslin, Donald, Atochina, Elena, Cines, Douglas B

“…A fibrinolytic agent consisting of a tissue-type plasminogen activator (tPA) coupled to the surface of red blood cells (RBCs) can dissolve nascent clots from…”
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Surfactant Protein D Protects against Acute Hyperoxic Lung Injury by Jain, Deepika, Atochina-Vasserman, Elena N, Tomer, Yaniv, Kadire, Helchem, Beers, Michael F

“…Surfactant protein D (SP-D) is a member of the collectin family of soluble, innate, host defense molecules with demonstrated immunomodulatory properties in…”
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Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers by Zhang, Dapeng, Atochina-Vasserman, Elena N, Maurya, Devendra S, Liu, Matthew, Xiao, Qi, Lu, Juncheng, Lauri, George, Ona, Nathan, Reagan, Erin K, Ni, Houping, Weissman, Drew, Percec, Virgil

“…Targeted and efficient delivery of nucleic acids with viral and synthetic vectors is the key step of genetic nanomedicine. The four-component lipid…”
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