Search Results - "Atkinson, M. A."

Does the gut microbiota have a role in type 1 diabetes? Early evidence from humans and animal models of the disease by Atkinson, M. A., Chervonsky, A.

“…Despite years of appreciating the potential role of environment to influence the pathogenesis of type 1 diabetes, specific agents or mechanisms serving in such…”
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The diagnosis of insulitis in human type 1 diabetes by Campbell-Thompson, M. L., Atkinson, M. A., Butler, A. E., Chapman, N. M., Frisk, G., Gianani, R., Giepmans, B. N., von Herrath, M. G., Hyöty, H., Kay, T. W., Korsgren, O., Morgan, N. G., Powers, A. C., Pugliese, A., Richardson, S. J., Rowe, P. A., Tracy, S., In’t Veld, P. A.

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The intestinal microbiome in type 1 diabetes by Dunne, J. L., Triplett, E. W., Gevers, D., Xavier, R., Insel, R., Danska, J., Atkinson, M. A.

“…Summary Few concepts in recent years have garnered more disease research attention than that of the intestinal (i.e. ‘gut’) microbiome. This emerging interest…”
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‘Pretty in Pink’ and ‘Girl Power’: An analysis of the targeting and representation of women in alcohol brand marketing on Facebook and Instagram by Atkinson, A.M., Meadows, B.R., Emslie, C., Lyons, A., Sumnall, H.R.

“…Alcohol marketing helps shape how gender roles and relations are understood, and the gendered nature of drinking learned. In recent years, changes in how women…”
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How to save a life: Public awareness of a national mass media take home naloxone campaign, and effects of exposure to campaign components on overdose knowledge and responses by Sumnall, HR, Atkinson, AM, Anderson, M, McAuley, A, Trayner, KMA

“…•A media campaign aimed to increase public awareness of drug deaths and naloxone.•There was relatively high levels of campaign recall and recognition by the…”
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Dimorphic histopathology of long-standing childhood-onset diabetes by Gianani, R, Campbell-Thompson, M, Sarkar, S. A, Wasserfall, C, Pugliese, A, Solis, J. M, Kent, S. C, Hering, B. J, West, E, Steck, A, Bonner-Weir, S, Atkinson, M. A, Coppieters, K, von Herrath, M, Eisenbarth, G. S

“…Aims/hypothesis Childhood diabetes is thought to usually result from autoimmune beta cell destruction (type 1A) with eventual total loss of beta cells…”
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Clinically relevant fatigue in men with hormone-sensitive prostate cancer on long-term androgen deprivation therapy by Storey, D.J., McLaren, D.B., Atkinson, M.A., Butcher, I., Frew, L.C., Smyth, J.F., Sharpe, M.

“…The purpose of the study was to determine the prevalence and associations of clinically relevant fatigue (CRF) in men with biochemically controlled prostate…”
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The Anatomical Society core regional anatomy syllabus for undergraduate medicine by Smith, C.F., Finn, G.M., Stewart, J., Atkinson, M.A., Davies, D.C., Dyball, R., Morris, J., Ockleford, C., Parkin, I., Standring, S., Whiten, S., Wilton, J., McHanwell, S.

“…The Anatomical Society's core syllabus for anatomy (2003 and later refined in 2007) set out a series of learning outcomes that an individual medical student…”
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Performance and image enhancing drug interventions aimed at increasing knowledge among healthcare professionals (HCP): reflections on the implementation of the Dopinglinkki e-module in Europe and Australia in the HCP workforce by Atkinson, A.M., van de Ven, K., Cunningham, M., de Zeeuw, T., Hibbert, E., Forlini, C., Barkoukis, V., Sumnall, H.R.

“…Healthcare professionals (HCPs) provide an important point of contact through which people who use performance and image enhancing drugs (PIEDs) could access…”
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The threshold hypothesis: solving the equation of nurture vs nature in type 1 diabetes by Wasserfall, C., Nead, K., Mathews, C., Atkinson, M. A.

“…For more than 40 years, the contributions of nurture (i.e. the environment) and nature (i.e. genetics) have been touted for their aetiological importance in…”
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‘We are still obsessed by this idea of abstinence’: A critical analysis of UK news media representations of proposals to introduce drug consumption rooms in Glasgow, UK by Atkinson, A.M., McAuley, A., Trayner, K.M.A., Sumnall, H.R.

“…Drug consumptions rooms (DCRs) are a well-established and evidence-based harm reduction response to drug use. Recently, a consortium led by health services in…”
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Validation of a rapid type 1 diabetes autoantibody screening assay for community‐based screening of organ donors to identify subjects at increased risk for the disease by Wasserfall, C., Montgomery, E., Yu, L., Michels, A., Gianani, R., Pugliese, A., Nierras, C., Kaddis, J. S., Schatz, D. A., Bonifacio, E., Atkinson, M. A.

“…Summary The Network for Pancreatic Organ donors with Diabetes (nPOD) programme was developed in response to an unmet research need for human pancreatic tissue…”
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Untargeted metabolomic analysis in non-fasted diabetic dogs by UHPLC–HRMS by O’Kell, A. L., Garrett, T. J., Wasserfall, C., Atkinson, M. A.

“…Introduction We recently identified variances in serum metabolomic profiles between fasted diabetic and healthy dogs, some having similarities to those…”
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Clinically relevant fatigue in recurrence-free prostate cancer survivors by Storey, D.J., McLaren, D.B., Atkinson, M.A., Butcher, I., Liggatt, S., O’Dea, R., Smyth, J.F., Sharpe, M.

“…Little is known about the prevalence and associations of clinically relevant fatigue (CRF) in recurrence-free prostate cancer survivors. Four hundred and…”
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Factors impeding the discovery of an intervention‐based treatment for type 1 diabetes by von Herrath, M. G., Korsgren, O., Atkinson, M. A.

“…Summary Type 1 diabetes (T1D) is one of the most common and severe chronic diseases affecting both children and adults. The aetiology of the disease remains…”
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Chronic glucokinase activator treatment at clinically translatable exposures gives durable glucose lowering in two animal models of type 2 diabetes by Baker, D J, Wilkinson, G P, Atkinson, A M, Jones, H B, Coghlan, M, Charles, A D, Leighton, B

“…Background and Purpose Pharmacological activation of glucokinase (GK) lowers blood glucose in animal models and humans, confirming proof of concept for this…”
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Predictive blood glucose lowering efficacy by Glucokinase activators in high fat fed female Zucker rats by Coope, G J, Atkinson, A M, Allott, C, McKerrecher, D, Johnstone, C, Pike, K G, Holme, P C, Vertigan, H, Gill, D, Coghlan, M P, Leighton, B

“…Background and purpose: Glucokinase (GK) is the rate‐limiting enzyme of hepatic glucose metabolism and acts as a sensor for glucose‐stimulated insulin release…”
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Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver by LOILER, S. A, CONLON, T. J, MUZYCZKA, N, FLOTTE, T. R, SONG, S, TANG, Q, WARRINGTON, K. H, AGARWAL, A, KAPTURCZAK, M, LI, C, RICORDI, C, ATKINSON, M. A

“…Human pancreatic islet cells and hepatocytes represent the two most likely target cells for genetic therapy of type I diabetes. However, limits to the…”
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Mobilization without immune depletion fails to restore immunological tolerance or preserve beta cell function in recent onset type 1 diabetes by Haller, M. J., Atkinson, M. A., Wasserfall, C. H., Brusko, T. M., Mathews, C. E., Hulme, M., Cintron, M., Shuster, J., McGrail, K., Posgai, A., Schatz, D.

“…Summary Granulocyte colony‐stimulating factor (G‐CSF) has been used to restore immune competence following chemoablative cancer therapy and to promote…”
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Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting critical mass of autoreactive T-cells in pancreatic islets by SERREZE, D. V, OTTENDORFER, E. W, ELLIS, T. M, GAUNTT, C. J, ATKINSON, M. A

“…Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting critical mass of autoreactive T-cells in pancreatic islets. D V Serreze ,…”
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