Search Results - "Atkins, Norman"
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1
Mass spectrometry-based discovery of circadian peptides
Published in Proceedings of the National Academy of Sciences - PNAS (26-08-2008)“…A significant challenge to understanding dynamic and heterogeneous brain systems lies in the chemical complexity of secreted intercellular messengers that…”
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Journal Article -
2
Falls, healthcare resources and costs in older adults with insomnia treated with zolpidem, trazodone, or benzodiazepines
Published in BMC geriatrics (04-06-2022)“…Falls are the leading cause of injury-related death among older Americans. While some research has found that insomnia heightens falls, health care resource…”
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3
Comparing Label-Free Quantitative Peptidomics Approaches to Characterize Diurnal Variation of Peptides in the Rat Suprachiasmatic Nucleus
Published in Analytical chemistry (Washington) (07-01-2014)“…Mammalian circadian rhythm is maintained by the suprachiasmatic nucleus (SCN) via an intricate set of neuropeptides and other signaling molecules. In this…”
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4
Lemborexant for the Treatment of Insomnia: Direct and Indirect Comparisons With Other Hypnotics Using Number Needed to Treat, Number Needed to Harm, and Likelihood to Be Helped or Harmed
Published in The journal of clinical psychiatry (01-06-2021)“…To describe lemborexant for the treatment of insomnia ( ) in adults using number needed to treat (NNT), number needed to harm (NNH), and likelihood to be…”
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Quantitative Peptidomics for Discovery of Circadian-Related Peptides from the Rat Suprachiasmatic Nucleus
Published in Journal of proteome research (01-02-2013)“…In mammals the suprachiasmatic nucleus (SCN), the master circadian clock, is sensitive to light input via the optic chiasm and synchronizes many daily…”
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Impact of lemborexant treatment on insomnia severity: analyses from a 12-month study of adults with insomnia disorder
Published in Sleep medicine (01-02-2022)“…Evaluate changes in insomnia severity in subjects with moderate to severe insomnia (Insomnia Severity Index [ISI] score ≥15) treated for 12 months nightly with…”
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7
Circadian integration of glutamatergic signals by little SAAS in novel suprachiasmatic circuits
Published in PloS one (07-09-2010)“…Neuropeptides are critical integrative elements within the central circadian clock in the suprachiasmatic nucleus (SCN), where they mediate both cell-to-cell…”
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Fall Risk, Healthcare Resource Use, and Costs Among Adult Patients in the United States Treated for Insomnia with Zolpidem, Trazodone, or Benzodiazepines: A Retrospective Cohort Study
Published in Advances in therapy (01-03-2022)“…Introduction Falls are a common cause for morbidity and mortality among patients taking prescription insomnia medication. The objective of this study is to…”
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Journal Article -
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Endogenous peptide discovery of the rat circadian clock: a focused study of the suprachiasmatic nucleus by ultrahigh performance tandem mass spectrometry
Published in Molecular & cellular proteomics (01-02-2010)“…Understanding how a small brain region, the suprachiasmatic nucleus (SCN), can synchronize the body's circadian rhythms is an ongoing research area. This…”
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Journal Article -
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Functional Peptidomics: Stimulus- and Time-of-Day-Specific Peptide Release in the Mammalian Circadian Clock
Published in ACS chemical neuroscience (15-08-2018)“…Daily oscillations of brain and body states are under complex temporal modulation by environmental light and the hypothalamic suprachiasmatic nucleus (SCN),…”
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11
The Patient Experience with DSM-5-Defined Binge Eating Disorder: Characteristics, Barriers to Treatment, and Implications for Primary Care Physicians
Published in Postgraduate medicine (01-09-2014)“…Background: Binge eating disorder (BED) is now a formal diagnosis in the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5). However,…”
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12
Direct cellular peptidomics of hypothalamic neurons
Published in Frontiers in neuroendocrinology (01-10-2011)“…Graphical abstract Research highlights ► Technological advances enable suites of peptides from hypothalamic neurons to be identified. ► Analytical chemistry…”
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Endogenous Peptide Discovery of the Rat Circadian Clock
Published in Molecular & cellular proteomics (01-02-2010)“…Understanding how a small brain region, the suprachiasmatic nucleus (SCN), can synchronize the body's circadian rhythms is an ongoing research area. This…”
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Journal Article -
14
Great habits, great readers: a practical guide for K-4 reading in the light of common core
Published 2013“…A book that brings the habits of reading to life Great readers are not made by genetics or destiny but by the habits they build—habits that are intentionally…”
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eBook -
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The together teacher: plan ahead, get organized, and save time!
Published 2012“…"An essential guide for over-scheduled teachers. Maia Heyck-Merlin helps teachers build the habits, customize the tools, and create space to become a Together…”
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Teach Like a Champion: 49 Techniques that Put Students on the Path to College
Published in Jossey-Bass, An Imprint of Wiley (01-04-2010)“…"Teach Like a Champion" offers effective teaching techniques to help teachers, especially those in their first few years, become champions in the classroom…”
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Functional Peptidomics: Combining Discovery-Based Mass Spectrometry and Neurophysiology to Explore Communication of Phase-Resetting Cues in the Rat Suprachiasmatic Nucleus
Published 2009“…Intercellular signaling is vital to communication within neuronal circuits. The suprachiasmatic nucleus (SCN), the master circadian clock of mammals, contains…”
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Dissertation -
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Effect of Lemborexant on Fatigue Severity and Sleep Outcomes Over 12 Months in Subjects With Clinically Significant Fatigue at Baseline (1593)
Published in Neurology (13-04-2021)“…Abstract only…”
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Journal Article -
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Effect of Lemborexant on Patient-Reported Distress About Sleeping and Interference with Daily Functioning in Subjects With Insomnia (1582)
Published in Neurology (13-04-2021)“…Abstract only…”
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Journal Article -
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335 Evaluation of Dose Transition From Zolpidem to Lemborexant Across 14 Weeks: Results From a Multicenter Open-label Pilot Study
Published in Sleep (New York, N.Y.) (03-05-2021)“…Abstract Introduction E2006-A001-312 (Study 312; NCT04009577) was an open-label pilot study that examined pre-specified dosing paradigms for transitioning…”
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