Search Results - "Athmer, Jeremiah"

The coronavirus nucleocapsid protein is ADP-ribosylated by Grunewald, Matthew E., Fehr, Anthony R., Athmer, Jeremiah, Perlman, Stanley

“…ADP-ribosylation is a common post-translational modification, although how it modulates RNA virus infection is not well understood. While screening for…”
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The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection by Fehr, Anthony R, Channappanavar, Rudragouda, Jankevicius, Gytis, Fett, Craig, Zhao, Jincun, Athmer, Jeremiah, Meyerholz, David K, Ahel, Ivan, Perlman, Stanley

“…ADP-ribosylation is a common posttranslational modification that may have antiviral properties and impact innate immunity. To regulate this activity,…”
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Virus-induced inflammasome activation is suppressed by prostaglandin D₂/DP1 signaling by Vijay, Rahul, Fehr, Anthony R., Janowski, Ann M., Athmer, Jeremiah, Wheeler, Dorthea L., Grunewald, Matthew, Sompallae, Ramakrishna, Kurup, Samarchith P., Meyerholz, David K., Sutterwala, Fayyaz S., Narumiya, Shuh, Perlman, Stanley

“…Prostaglandin D2 (PGD₂), an eicosanoid with both pro- and antiinflammatory properties, is the most abundantly expressed prostaglandin in the brain. Here we…”
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Nasal priming by a murine coronavirus provides protective immunity against lethal heterologous virus pneumonia by Hua, Xiaoyang, Vijay, Rahul, Channappanavar, Rudragouda, Athmer, Jeremiah, Meyerholz, David K, Pagedar, Nitin, Tilley, Stephen, Perlman, Stanley

“…The nasal mucosa is an important component of mucosal immunity. Immunogenic particles in inspired air are known to activate the local nasal mucosal immune…”
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Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses by Athmer, Jeremiah, Fehr, Anthony R, Grunewald, Matthew E, Qu, Wen, Wheeler, D Lori, Graepel, Kevin W, Channappanavar, Rudragouda, Sekine, Aimee, Aldabeeb, Dana Saud, Gale, Jr, Michael, Denison, Mark R, Perlman, Stanley

“…Selective packaging is a mechanism used by multiple virus families to specifically incorporate genomic RNA (gRNA) into virions and exclude other types of RNA…”
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Two Commercially Available Blood-Stabilization Reagents Serve as Potent Inactivators of Coronaviruses by O'Connor, Joseph J, Voth, Lynden, Athmer, Jeremiah, George, Nicholas M, Connelly, Christopher M, Fehr, Anthony R

“…The continued circulation of SARS-CoV-2 and the increasing frequency of coronavirus (CoV) outbreaks over the decades demonstrates the enduring threat that the…”
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The nsp3 macrodomain promotes virulence in mice with coronavirus-induced encephalitis by Fehr, Anthony R, Athmer, Jeremiah, Channappanavar, Rudragouda, Phillips, Judith M, Meyerholz, David K, Perlman, Stanley

“…All coronaviruses encode a macrodomain containing ADP-ribose-1"-phosphatase (ADRP) activity within the N terminus of nonstructural protein 3 (nsp3). Previous…”
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Murine Olfactory Bulb Interneurons Survive Infection with a Neurotropic Coronavirus by Wheeler, D Lori, Athmer, Jeremiah, Meyerholz, David K, Perlman, Stanley

“…Viral infection of the central nervous system (CNS) is complicated by the mostly irreplaceable nature of neurons, as the loss of neurons has the potential to…”
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Virus-induced inflammasome activation is suppressed by prostaglandin D 2 /DP1 signaling by Vijay, Rahul, Fehr, Anthony R, Janowski, Ann M, Athmer, Jeremiah, Wheeler, Dorthea L, Grunewald, Matthew, Sompallae, Ramakrishna, Kurup, Samarchith P, Meyerholz, David K, Sutterwala, Fayyaz S, Narumiya, Shuh, Perlman, Stanley

“…Prostaglandin D2 (PGD ), an eicosanoid with both pro- and anti-inflammatory properties, is the most abundantly expressed prostaglandin in the brain. Here we…”
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In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins by Athmer, Jeremiah, Fehr, Anthony R, Grunewald, Matthew, Smith, Everett Clinton, Denison, Mark R, Perlman, Stanley

“…Coronavirus (CoV) replication and transcription are carried out in close proximity to restructured endoplasmic reticulum (ER) membranes in…”
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New Insights into Nsp15 Protein and RNA Elements During Mouse Hepatitis Virus Infection by Athmer, Jeremiah

“…The non-structural protein 15 (nsp15) locus in Lineage A β-coronaviruses has two important functions during replication. The encoded endoribonuclease is…”
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Virus-induced inflammasome activation is suppressed by prostaglandin D^sub 2^/DP1 signaling by Vijay, Rahul, Fehr, Anthony R, Janowski, Ann M, Athmer, Jeremiah, Wheeler, Dorthea L, Grunewald, Matthew, Sompallae, Ramakrishna, Kurup, Samarchith P, Meyerholz, David K, Sutterwala, Fayyaz S, Narumiya, Shuh, Perlman, Stanley

“…Prostaglandin D2 (PGD2), an eicosanoid with both pro- and anti-inflammatory properties, is the most abundantly expressed prostaglandin in the brain. Here we…”
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italic toggle="yes">In Situ /italic> Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins by Jeremiah Athmer, Anthony R. Fehr, Matthew Grunewald, Everett Clinton Smith, Mark R. Denison, Stanley Perlman

“…ABSTRACT Coronavirus (CoV) replication and transcription are carried out in close proximity to restructured endoplasmic reticulum (ER) membranes in…”
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