Leptin levels in gingival crevicular fluid during orthodontic tooth movement

To test if leptin can be detected in the gingival crevicular fluid (GCF) around moving teeth, and to determine whether any changes occur during orthodontic tooth movement. An upper canine requiring distal movement served as the test tooth; the contralateral canine was used as a control tooth. The co...

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Bibliographic Details
Published in:	The Angle orthodontist Vol. 80; no. 3; pp. 504 - 508
Main Authors:	Dilsiz, Alparslan, Kiliç, Nihat, Aydin, Tugba, Ates, F Nesibe, Zihni, Meltem, Bulut, Caglar
Format:	Journal Article
Language:	English
Published:	United States Edward H Angle Education and Research Foundation, Inc 01-05-2010
Subjects:	Adolescent Cuspid - pathology Dental Plaque Index Female Follow-Up Studies Gingival Crevicular Fluid - chemistry Gingival Hemorrhage - classification Humans Leptin - analysis Male Original Periodontal Index Periodontal Pocket - classification Prospective Studies Tooth Movement Techniques
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Summary:	To test if leptin can be detected in the gingival crevicular fluid (GCF) around moving teeth, and to determine whether any changes occur during orthodontic tooth movement. An upper canine requiring distal movement served as the test tooth; the contralateral canine was used as a control tooth. The control tooth was included in the orthodontic appliance, but was not subjected to the orthodontic force. GCF sampling from the distal sites of the test and control teeth was done at baseline, 1 hour, 24 hours, and 168 hours. Leptin concentrations of the test teeth decreased in a time-dependent manner. When compared with the baseline measurement, the decrease was significant at 168 hours (P < .05). The concentration of leptin in GCF is decreased by orthodontic tooth movement; the results of the present study also suggest that leptin may have been one of the mediators responsible for orthodontic tooth movement.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23
ISSN:	0003-3219 1945-7103
DOI:	10.2319/072109-402.1