Search Results - "Atef, Eman"
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Transferrin-Conjugated Nanostructured Lipid Carriers for Targeting Artemisone to Melanoma Cells
Published in International journal of molecular sciences (22-08-2024)“…We report a successful formulation of Artemisone (ATM) in transferrin (Tf)-conjugated nanostructured lipid carriers (NLCs), achieving nearly a five-times…”
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2
Amorphous stabilization and dissolution enhancement of amorphous ternary solid dispersions: combination of polymers showing drug-polymer interaction for synergistic effects
Published in Journal of pharmaceutical sciences (01-11-2014)“…The purpose of this study was to understand the combined effect of two polymers showing drug-polymer interactions on amorphous stabilization and dissolution…”
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3
Role of Molecular Interactions for Synergistic Precipitation Inhibition of Poorly Soluble Drug in Supersaturated Drug–Polymer–Polymer Ternary Solution
Published in Molecular pharmaceutics (07-03-2016)“…We are reporting a synergistic effect of combined Eudragit E100 and PVP K90 in precipitation inhibition of indomethacin (IND) in solutions at low polymer…”
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4
Correlating the behavior of polymers in solution as precipitation inhibitor to its amorphous stabilization ability in solid dispersions
Published in Journal of pharmaceutical sciences (01-06-2013)“…Our major goals were to understand the mechanism of dipyridamole (DPD) precipitation inhibition in the presence of polymers and to correlate the…”
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5
Adaptive office buildings: improving functional flexibility in response to shifting needs using kinetic technology
Published in Architectural engineering and design management (03-07-2024)“…Architectural flexibility, a critical aspect of building design, can be considered as one of the most important principles of contemporary architectural…”
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Hydrogen Bonding: Between Strengthening the Crystal Packing and Improving Solubility of Three Haloperidol Derivatives
Published in Molecules (Basel, Switzerland) (01-06-2016)“…The purpose of this study is to confirm the impact of polar functional groups on inter and intra-molecular hydrogen bonding in haloperidol (HP) and droperidol…”
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7
Can a monthly exenatide extended release regimen provide a therapeutic and cost benefit?
Published in Biopharmaceutics & drug disposition (01-06-2021)“…Exenatide is used to treat type 2 diabetes mellitus. The current regimen is a 2 mg extended release (ER) weekly injection. The aim of our study was to prove…”
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Correlation of Inhibitory Effects of Polymers on Indomethacin Precipitation in Solution and Amorphous Solid Crystallization Based on Molecular Interaction
Published in Pharmaceutical research (01-02-2014)“…Purpose To correlate the polymer’s degree of precipitation inhibition of indomethacin in solution to the amorphous stabilization in solid state. Methods…”
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Resistance Realized Heritability and Fitness Cost of Cyproflanilide in Rice Stem Borer, Chilo suppressalis (Lepidoptera: Pyralidae)
Published in Agronomy (Basel) (01-10-2024)“…The rice stem borer (RSB) Chilo suppressalis is a devastating rice pest with resistance to a number of insecticides. Recently, the new meta-diamide insecticide…”
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10
PBPK Evaluation of Sofosbuvir Dose in Pediatrics Using Simcyp
Published in Scientia pharmaceutica (01-08-2023)“…The aim of the study is to evaluate the effectiveness of the pediatric sofosbuvir weight-based dosing strategy in providing an equitable drug exposure compared…”
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Neuropsychiatric comorbidities in adult patients with new-onset epilepsy
Published in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery (16-09-2024)“…BackgroundNeuropsychiatric comorbidities in adult patients with new-onset epilepsy in our university hospitals has not been assessed, so the purpose of this…”
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Profile of adult -onset epilepsy in Zagazig university hospitals
Published in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery (10-05-2024)“…BackgroundEpilepsy has many neurobiological consequences. This study aimed to identify the profile of adult patients with new onset epilepsy in our university…”
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13
The role of detoxifying enzymes in the resistance of the cowpea aphid (Aphis craccivora Koch) to thiamethoxam
Published in Journal of plant protection research (01-01-2016)“…The cowpea aphid (Aphis craccivora Koch) is considered a serious insect pest attacking several crops. We carried out biochemical studies to elucidate the role…”
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14
A Low-Power Modified Strong-ARM Latch-Based Comparator for Biomedical Applications in 130nm CMOS Technology
Published in 2023 11th International Japan-Africa Conference on Electronics, Communications, and Computations (JAC-ECC) (18-12-2023)“…SAR ADC comparators occupy 50%-60% of the total energy consumption, even with advanced technology and lower supply voltages. Comparator design represents a…”
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Conference Proceeding -
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Using Raman Spectroscopy in Studying the Effect of Propylene Glycol, Oleic Acid, and Their Combination on the Rat Skin
Published in AAPS PharmSciTech (2018)“…The permeability enhancement effect of oleic acid (OA) and propylene glycol (PG) as well as their (1:1 v /v) combined mixture was studied using rat skin. The…”
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Characterization of Self-Emulsifying Drug Delivery Systems Using In Situ Raman Spectroscopy to Study the Precipitation Inhibition Mechanism of Poorly Water-Soluble Drugs
Published in Journal of pharmaceutical innovation (01-06-2018)“…Purpose The goal of this research was to study the molecular interactions in situ between actives and surfactants in self-emulsifying delivery systems (SEDDS)…”
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Using in situ Raman spectroscopy to study the drug precipitation inhibition and supersaturation mechanism of Vitamin E TPGS from self-emulsifying drug delivery systems (SEDDS)
Published in Journal of pharmaceutical and biomedical analysis (10-05-2015)“…•SEDDS using Labrasol® or TPGS were formulated for two poorly soluble drugs.•High levels of supersaturation were achieved from Vitamin E TPGS SEDDS.•Raman…”
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18
Benzimidazole scaffold as a potent anticancer agent with different mechanisms of action (2016-2023)
Published in Molecular diversity (20-07-2024)“…Benzimidazole scaffolds have potent anticancer activity due to their structure similarity to nucleoside. In addition, benzimidazoles could function as hydrogen…”
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Formulation and in vitro and in vivo characterization of a phenytoin self-emulsifying drug delivery system (SEDDS)
Published in European journal of pharmaceutical sciences (15-11-2008)“…The aim of this study is to develop and characterize a self-emulsifying drug delivery system (SEDDS) of phenytoin, and to compare its relative bioavailability…”
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Studying the effect of lipid chain length on the precipitation of a poorly water soluble drug from self-emulsifying drug delivery system on dispersion into aqueous medium
Published in Journal of pharmacy and pharmacology (01-08-2013)“…Objective The lipid excipients of the self‐emulsifying drug delivery systems (SEDDS) could play a role in interfering with the drug precipitation to maintain…”
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