Search Results - "Ataya, Michelle"
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NK cells eliminate Epstein-Barr virus bound to B cells through a specific antibody-mediated uptake
Published in PLoS pathogens (20-08-2021)“…Epstein Barr virus (EBV) causes a highly prevalent and lifelong infection contributing to the development of some malignancies. In addition to the key role…”
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Human Cytomegalovirus Antigen Presentation by HLA-DR+ NKG2C+ Adaptive NK Cells Specifically Activates Polyfunctional Effector Memory CD4+ T Lymphocytes
Published in Frontiers in immunology (2019)“…Natural killer (NK) cells play a dual role in the defense against viral pathogens by directly lysing infected cells as well as by regulating anti-viral T cell…”
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Adaptive NKG2C+ natural killer cells are related to exacerbations and nutritional abnormalities in COPD patients
Published in Respiratory research (04-03-2020)“…Chronic obstructive pulmonary disease (COPD) is a chronic and often progressive disorder with a heterogeneous presentation and frequent systemic…”
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1 Nilogen Oncosystem’s 3D-EXpress platform allows rapid assessment of mono and combo targeted and immune therapies using a biorepository of fresh patient tumoroids with intact tumor microenvironment
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundIt has been a significant challenge to select, combine and sequence the multiple FDA-approved IO therapies and pharmaceutical agents, highlighting…”
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2 Nilogen oncosystems’s 3D-PREDICT tumoroid model is an ex vivo precision oncology and co-clinical trial enrichment platform
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundImmuno-oncology (IO) therapy with checkpoint inhibitors has demonstrated higher response rate, duration of response, and overall survival than…”
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Abstract 951: 3D-PREDICT - An ex vivo precision oncology and clinical trial enrichment platform by Nilogen Oncosystems
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Background: Immuno-oncology (IO) therapy with checkpoint inhibitors has demonstrated a higher response rate, duration of response, and overall…”
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Abstract 6782: 3D-EXpress - an ex vivo platform using viably cryopreserved tumoroids for rapid assessment of targeted therapeutic outcomes
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Background: it has been a significant challenge to select, combine, and sequence the multiple FDA-approved IO therapies and pharmaceutical agents,…”
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Long-Term Evolution of the Adaptive NKG2C+ NK Cell Response to Cytomegalovirus Infection in Kidney Transplantation: An Insight on the Diversity of Host–Pathogen Interaction
Published in The Journal of immunology (1950) (01-10-2021)“…Abstract Human CMV infection is frequent in kidney transplant recipients (KTR). Pretransplant Ag-specific T cells and adaptive NKG2C+ NK cells associate with…”
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CD137 Costimulation Counteracts TGFβ Inhibition of NK-cell Antitumor Function
Published in Cancer immunology research (01-12-2021)“…Enhancing natural killer (NK) cell-based cancer immunotherapy by overcoming immunosuppression is an area of intensive research. Here, we have demonstrated that…”
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Pretransplant adaptive NKG2C+ NK cells protect against cytomegalovirus infection in kidney transplant recipients
Published in American journal of transplantation (01-03-2020)“…Cytomegalovirus (CMV) infection constitutes a complication for kidney transplant recipients (KTR) and CMV‐specific T cells reduce the risk of viral replication…”
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