Search Results - "Atauri Carulla, Ramón de"
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From correlation to causation: analysis of metabolomics data using systems biology approaches
Published in Metabolomics (2018)“…Introduction Metabolomics is a well-established tool in systems biology, especially in the top–down approach. Metabolomics experiments often results in…”
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Oncogenic regulation of tumor metabolic reprogramming
Published in Oncotarget (20-09-2016)“…Development of malignancy is accompanied by a complete metabolic reprogramming closely related to the acquisition of most of cancer hallmarks. In fact, key…”
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3
De novo MYC addiction as an adaptive response of cancer cells to CDK4/6 inhibition
Published in Molecular systems biology (04-10-2017)“…Cyclin‐dependent kinases (CDK) are rational cancer therapeutic targets fraught with the development of acquired resistance by tumor cells. Through metabolic…”
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Sampling with poling-based flux balance analysis: optimal versus sub-optimal flux space analysis of Actinobacillus succinogenes
Published in BMC bioinformatics (18-02-2015)“…Flux balance analysis is traditionally implemented to identify the maximum theoretical flux for some specified reaction and a single distribution of flux…”
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Sampling with poling-based flux balance analysis: optimal versus sub-optimal flux space analysis of Actinobacillus succinogenes
Published in BMC bioinformatics (18-02-2015)“…Flux balance analysis is traditionally implemented to identify the maximum theoretical flux for some specified reaction and a single distribution of flux…”
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Untargeted metabolomics reveals distinct metabolic reprogramming in endothelial cells co-cultured with CSC and non-CSC prostate cancer cell subpopulations
Published in PloS one (21-02-2018)“…Tumour angiogenesis is an important hallmark of cancer and the study of its metabolic adaptations, downstream to any cellular change, can reveal attractive…”
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Network modules uncover mechanisms of skeletal muscle dysfunction in COPD patients
Published in Journal of translational medicine (20-02-2018)“…BACKGROUND: Chronic obstructive pulmonary disease (COPD) patients often show skeletal muscle dysfunction that has a prominent negative impact on prognosis. The…”
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Network modules uncover mechanisms of skeletal muscle dysfunction in COPD patients
Published in Journal of translational medicine (20-02-2018)“…BACKGROUND: Chronic obstructive pulmonary disease (COPD) patients often show skeletal muscle dysfunction that has a prominent negative impact on prognosis. The…”
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Effects of cadmium and mercury on the upper part of skeletal muscle glycolysis in mice
Published in PloS one (28-01-2014)“…The effects of pre-incubation with mercury (Hg(2+)) and cadmium (Cd(2+)) on the activities of individual glycolytic enzymes, on the flux and on internal…”
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HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates 13C Isotopomer Data
Published in PLoS computational biology (28-04-2016)“…The liver performs many essential metabolic functions, which can be studied using computational models of hepatocytes. Here we present HepatoDyn, a highly…”
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ChainRank, a chain prioritisation method for contextualisation of biological networks
Published in BMC bioinformatics (05-01-2016)“…Advances in high throughput technologies and growth of biomedical knowledge have contributed to an exponential increase in associative data. These data can be…”
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Workforce preparation: the Biohealth computing model for Master and PhD students
Published in Journal of translational medicine (28-11-2014)“…The article addresses the strategic role of workforce preparation in the process of adoption of Systems Medicine as a driver of biomedical research in the new…”
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Workforce preparation: the Biohealth computing model for Master and PhD students
Published in Journal of translational medicine (28-11-2014)“…The article addresses the strategic role of workforce preparation in the process of adoption of Systems Medicine as a driver of biomedical research in the new…”
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